Clinical symptoms of acute appendicitis correlating to its intraoperative anatomical position by Chandan Singh, Aamina Hamdule, Amey Kasbekar, Shishir Kamble

“…The precise localisation of the appendix is critical for timely diagnosis and therapy. Objectives: The purpose of this study was to look at the relationship between clinical symptoms of acute appendicitis and the appendix's anatomical position during surgery. …”
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Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma by Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly

“…Erdafitinib is an oral fibroblast growth factor receptor (FGFR) kinase inhibitor approved by the FDA for the treatment of adults with la/mUC harboring FGFR alterations whose disease progressed following at least 1 prior line of therapy, including a PD-1 or PD-L(1) inhibitor, based on the phase 3, randomized THOR trial (NCT03390504, Cohort 1). …”
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Ultrasound Presentation of a Disseminated Fetal and Neonatal Rhabdoid Tumor by Yolaine Joueidi, Aline Rousselin, Céline Rozel, Philippe Loget, Dominique Ranchere Vince, Sylvie Odent, Franck Bourdeaut, Vincent Lavoue, Maela Le Lous

“…This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. …”
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Effect of Dynamic Neuromuscular Stabilization Exercises on Activity of External Oblique Muscle in Low Back Pain by Hediyeh Hosseini, Abbas Rahimi, Khodabakhsh Javanshir, Mohammad Taghipour, Aliyeh Daryabor, Sedigheh Sadat Naimi

“…The control group received standard physical therapy exercises, while the experimental group performed DNS exercises. …”
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Effects of Corneal Stromal Lens Collagen Cross-Linking Regraft on Corneal Biomechanics by Rong Shi, Weize Wang, Yu Che, Shaorong Linghu, Taixiang Liu

“…Corneal collagen cross-linking (CXL) therapy, a method that uses a combination of riboflavin and ultraviolet-A light (UVA), can promote the formation of covalent cross-linking of amino acid residues of corneal collagen and enhance the hardness of the cornea. …”
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Efficacy of High-Dose and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcomes in Patient with Acute Ischemic Stroke: A Randomized, Double-Blind, Parallel, C... by Nattaphol Uransilp, Pannawat Chaiyawatthanananthn, Sombat Muengtaweepongsa

“…Serum sLOX-1 and NO levels and neurological outcomes including NIHSS, mRS, and Barthel index were tested at baseline and Day 90 after simvastatin therapy. Results. Baseline characteristics were not significantly different in both groups except history of hypertension. …”
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The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet—Remaining Challenges in Hepatitis C by Nicholas van Buuren, Lorraine Fradette, Jason Grebely, Alexandra King, Mel Krajden, Sonya A. MacParland, Alison Marshall, Sahar Saeed, Joyce Wilson, Marina B. Klein, Selena M. Sagan

“…In 2015, the introduction of new interferon- (IFN-) free therapies with high cure rates (>90%) and few side effects revolutionized HCV therapy. …”
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Correlation Between the Grade of Hydronephrosis with Surgical Outcomes After Ultrasound-guided Supine Percutaneous Nephrolithotomy: A Retrospective Observational Study by Tiopan NAPITUPULU, Yosua HARDJA, Martin SUSANTO, Grace Dumamawarni HUTAHAEAN, Ika RIANTRI, Hendra SUTAPA, Yusuf RACHMAN, Andre Marolop Pangihutan SIAHAAN

“…Objective: The preferred therapy for staghorn stones and large kidney stones is percutaneous nephrolithotomy (PCNL). …”
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A rare case of acute myocardial infarction with heart failure following hump-nosed viper bite in a Sri Lankan female by W. M. D. A. S. Wanninayake, Tilan Aponso, Manohari Seneviratne, Dhanapala Dissanayake

“…We performed a CT coronary angiography along with a metabolic screening, revealing normal coronary arteries and a negative metabolic screening. Supportive therapy with loop diuretics and oxygen managed her condition, and a follow-up 2D echocardiogram revealed complete recovery of her cardiac function. …”
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Orthodontic interventions as a management option for children with residual obstructive sleep apnea: a cohort study protocol by Carlos Flores-Mir, Nathalia Carolina Fernandes Fagundes, Arnaldo Perez-Garcia, Daniel Graf, Giseon Heo

“…There are no established standard management approaches when the first line of therapy, the tonsillectomy and adenoidectomy (T&A), is not indicated or fails to address paediatric OSA (residual paediatric OSA). …”
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The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study by Wenya Pei, Boyu Jiao, Zexiong Chen, Jingchun Zeng, Yancheng Fu, Zhanmou Liang, Baoguo Sun, Jingwen Ruan, Shijun Zhang

“…Introduction: Traditional Chinese medicine is widely used as adjuvant therapy for hepatocellular carcinoma (HCC), but no relevant bibliometric study has comprehensively analyzed the available data. …”
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Comparing the effectiveness of different exercise interventions on quality of life in stroke patients: a randomized controlled network meta-analysis by Liqun Jiang, Huimin Ding, Qishuai Ma, Shang Gao, Xinxin Zhang, Buongo Chun

“…DTOT (Dual-task oriented training)was most effective for Quality of Life, Mental Health, and Upper Limb Function; AQE (Aquatic Exercise) for Physical Health and Social Participation; ST(Strength Training) for Pain and Vitality; CIT(Constraint-Induced Therapy) for Mobility and Recovery; BCT for Memory and Thinking; ALCE(Aquatic and Land Combined Exercise) for Emotion and ADL; and ULT(Upper Limb Training) for Communication. …”
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Pola Kepekaan Bakteri Penyebab Pneumonia terhadap Antibiotika di Laboratorium Mikrobiologi RSUP Dr. M. Djamil Padang Periode Januari sampai Desember 2011 by Jaka Kurniawan, Erly ., Rima Semiarty

“…<br />Kata kunci: antibiotika, bakteri penyebab pneumonia, pola kepekaan</p><p> </p><p>Abstract</p><p>Increased resistance of bacteria that cause pneumonia to some antibiotics that are commonly used by clinicians in the provision of empiric therapy, it will cause a reduction in the effectiveness of the treatment of pneumonia. …”
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Prognostic Relevance and Function of MSX2 in Colorectal Cancer by Jiancheng Liu, Huaying An, Wei Yuan, Qiang Feng, Lianzhen Chen, Jie Ma

“…In conclusion, MSX2 played a crucial role in the progression of CRC and may be a potential novel prognostic factor and therapeutic target for CRC therapy. Our work may provide certain enlightenment for investigating the mechanism of MSX2 in the process of diabetes.…”
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Impaired network organization in mild age‐related hearing loss by Zhaopeng Tong, Chunhua Xing, Xiaomin Xu, Jin‐Jing Xu, Yuanqing Wu, Richard Salvi, Xindao Yin, Fei Zhao, Yu‐Chen Chen, Yuexin Cai

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Predictive factors for clinical cure in the treatment of HBeAg(−) chronic hepatitis B or compensated cirrhosis: a prospective observational study by Yan-Qing Lv, Ru-Hua Guo, Kun-Yu Liu, Jia-Jie Li, Hui-Fan Ji

“…However, its clinical application is limited due to the adverse reactions associated with IFN.MethodsA multi-center prospective observational study was conducted involving 59 NAs-treated chronic hepatitis B (CHB) patients who were treated with a combination therapy of NAs and Peg-IFN-α-2b for 48 weeks. Another 327 NAs-treated patients received NAs monotherapy for 48 weeks. …”
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Comparison of Ticagrelor and Clopidogrel in Elective Coronary Stenting: A Double Blind Randomized Clinical Trial by Mohammadjavad Mehdizadeh Parizi, Reza Golchin Vafa, Amin Ahmadi, Reza Heydarzade, Mehrdad Sadeghi, Amin Khademolhossseini, Farhang Amiri, Soroush Khoshnood Mansorkhani, Ali Tavan, Nazanin Hosseini, Mohammad Montaseri, Seyed Ali Hosseini, Javad Kojuri

“…Background. Dual antiplatelet therapy with a P2Y12 inhibitor (e.g., clopidogrel and ticagrelor) and aspirin is recommended for at least one year after percutaneous coronary intervention (PCI) to prevent further myocardial infarction and stent thrombosis as the major adverse effects of PCI. …”
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Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma by Miaodong Wang, Qin He, Zeshan Chen, Yijue Qin

“…Patients in the high-CMLS group had a significantly poorer prognosis and were less sensitive to immunotherapy but were likely to benefit more from chemotherapy and targeted therapy. In this study, 10 clustering methods and 10 machine learning methods were combined to analyze the multiomics of STAD, classify STAD into three subtypes, and constructed CMLS-related prognostic model features, which are important for accurate management and effective treatment of STAD.…”
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Revealing the impact of tadalafil-loaded proniosomal gel against dexamethasone-delayed wound healing via modulating oxido-inflammatory response and TGF-β/Macrophage activation path... by Nermin A Helmy, Elsayed A Abdel Aziz, Mustafa Abd El Raouf, Reda M S Korany, Doaa A Mansour, Sara M Baraka, Arwa A Hassan, Eman Gomaa, Mennatullah M Faisal, Walaa A A Basha, Esraa M Fahmy, Rashed A Alhotan, Anam Ayyoub, Shaimaa Selim

“…Overall, the topical application of TAD-loaded proniosomal gel is useful in improving the delayed wound healing linked to DEX therapy via regulating the release of inflammatory/macrophage activation mediators and enhanced antioxidant capacity, angiogenesis, and vascularity.…”
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Peculiarities of cardio-respiratory relationships in qualified athletes with different types of heart rhythm regulation according to respiratory maneuver data by Oleksandr Romanchuk, Oleksandr Romanchuk

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