Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes by Qiang Su, Wei Kuang, Weiyi Hao, Jing Liang, Liang Wu, Chunmei Tang, Yali Wang, Tao Liu

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Vacuum-Assisted Closure and Muscle Flap as An Alternative Modality for Infected Wound After Orif of Tibial Fracture: Case Report by OK Ilham Abdullah Irsyam, Saraswati Hastika, Hendra Hendra, Andrew Budiartha Budisantoso, Tesar Akbar Nugraha

“…The case shows that VAC application and muscle flap therapy provide the definitive healing of infected wounds after ORIF. …”
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Review of Acupuncture and Moxibustion Treatment of Neurogenic Bladder after Spinal Cord Injury by Qianqian LIN, Chengmei LIU, Kewei CHEN, Huijie DUAN

“…Acupuncture, moxibustion, acupoint injection and comprehensive therapy were commonly used in the treatment of NB after SCI.In the acupuncture and moxibustion treatment of NB after SCI, acupoints selection mostly follow the principle of meridian selection and local acupoint selection. …”
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Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society by V. T. Ivashkin, M. V. Mayevskaya, Ch. S. Pavlov, Yu. P. Sivolap, V. D. Lunkov, M. S. Zharkova, R. V. Maslennikov

“…Specific pharmaceutical therapy is carried out at alcoholic hepatitis in relation to severity and alcoholic liver cirrhosis. …”
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Impact of the COVID-19 pandemic on cerebral venous sinus thrombosis in China: a comparative study by Xiaoming Zhang, Kun Fang, Duo Lan, Xiangqian Huang, Xunming Ji, Ran Meng, Da Zhou

“…Poor outcomes were associated with central nervous system (CNS) infection, oral contraceptive use or hormone replacement therapy (HRT), hematologic disorders, anemia, and prothrombotic conditions. …”
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Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis by Huan Han, Hanwen Su, Zhihua Lv, Chengliang Zhu, Jingtao Huang

“…The treatment of it is currently based on surgical removal, radiotherapy, and hormone therapy. It is crucial to improve therapeutic prospects for the diagnosis and treatment of prostate cancer via drug target screening. …”
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Efficacy and safety of high-intensity focused ultrasound combined with suction curettage for the treatment of caesarean scar pregnancy: a systematic review and single-arm meta-anal... by Yu Jiang, Yang Liu, Nian Liu, Shize Qin, Shuting Zhong, Xiaohua Huang

“…Intraoperative blood loss, treatment success rate, and reproductive results were the primary outcomes assessed.Results A total of 18 studies involving 1251 patients with CSP, all of whom received preoperative HIFU therapy were included. The average hospital stay was 6.22 days, the intraoperative blood loss was 26.29 ml and the incidence of adverse events was 15.60%, including abdominal or lower limb pain, fever, vaginal bleeding, haematuria and vomiting. …”
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Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review by Deenadhayalan Ashok, Monisha Prasad, Mohammad Fareed, Anis Ahmad Chaudhary

“…Epigenetic biomarkers could be helpful for risk assessment, early diagnosis, and tailored therapy for people with T2DM who are at risk or who have already been diagnosed. …”
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Emodin Enhanced Microwave‐Responsive Heterojunction with Powerful Bactericidal Capacity and Immunoregulation for Curing Bacteria‐Infected Osteomyelitis by Tao Xu, Hao Cheng, Hailiang Pei, Jiameng Wang, Yiwei Shi, Xiangyu Zhang, Di Huang

“…Abstract Eradication of osteomyelitis caused by bacterial infections is still a major challenge. Microwave therapy has the inherent advantage of deep penetration in curing deep tissue infections. …”
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CLINICAL SIGNS AND TREATMENT OF NEW-ONSET BONE MARROW FAILURE ASSOCIATED SARS-COV-2 INFECTION IN CHILDREN : A SINGLE INSTITUTION PROSPECTIVE COHORT STUD by Mervat A M youssef, Ebtisam Shawky hmed, Dalia Tarik Kamal, khalid Elsayh, Mai A Abdelfatta, Hyam Hassan Mahran Mahran, Mostafa M Embaby

“…Studies are needed to establish a definitive association and determine whether the response of bone marrow failure to standard therapy differ from that of idiopathic cases. …”
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Prevalence and predictors of severe Crohn’s disease at a tertiary hospital in South Africa by C Gounden, V Naidoo, Y Moodley

“… Background Predicting severe Crohn's disease (SCD) can assist in planning risk reduction therapy for SCD, thereby improving disease outcomes. …”
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Three-dimensional dynamics of mesothelin-targeted CAR.CIK lymphocytes against ovarian cancer peritoneal carcinomatosis by Federica Galvagno, Valeria Leuci, Annamaria Massa, Chiara Donini, Ramona Rotolo, Sonia Capellero, Alessia Proment, Letizia Vitali, Andrea Maria Lombardi, Valentina Tuninetti, Lorenzo D’Ambrosio, Alessandra Merlini, Elisa Vigna, Giorgio Valabrega, Luca Primo, Alberto Puliafito, Dario Sangiolo

“…Our findings provide currently unknown therapeutically relevant information on intraperitoneal approaches with CAR.CIK, supporting further developments and improvements for clinical studies in the context of locoregional cell therapy approaches for patients with PC from OC.…”
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Knowledge and Practice of Neonatal Pain Management and Associated Factors among Health Care Providers in Neonatal Intensive Care Units of Public Hospitals in North Shoa Zone, Amhar... by Abraraw Admasu Jember, Eyosiyas Yeshialem Asefa, Abdurahman Mohammed Ahmed, Addis Yeshitila Kidane

“…Despite recent advancements in the assessment and therapy of children’s pain, a knowledge-to-practice gap still exists especially in developing nations including our country Ethiopia. …”
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RNF138 contributes to cisplatin resistance in nasopharyngeal carcinoma cells by Hangyu Xu, Qing Yin, Linna Fan, Yating Zhao, Biying Song, Qifan Xu, Jie Zhu, Meifen Xu

“…These findings indicate that the modulation of RNF138 could potentially address the issue of chemotherapy failure by overcoming cisplatin resistance in NPC cells, making it a promising candidate for targeted drug therapy.…”
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Inpatient treatment for severe obesity: A retrospective cohort study in Brazil, comparing exposure variables in a secondary data analysis. by Domingos L S Rios, Márcia C A M Oliveira, Sérgio Q Braga, Matheus J Chamorro, Beatriz L B Cunha, Ana C R Reis, Ana P Guimarães, Ana D N Silva, Dandara A R Silva, Edilene M Q Araújo, Magno M W Pimentel

“…However, large studies providing a comprehensive longitudinal observation of patients undergoing this therapy are lacking. We evaluated the effectiveness of treating severe obesity in hospitalized patients, using very low-calorie diets and clinical support to develop lifestyle changes.…”
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Cytopenia among CML Patients on Imatinib in Kenya: Types, Grades, and Time Course by Angela McLigeyo, Jamilla Rajab, Mohammed Ezzi, Peter Oyiro, Yatich Bett, Andrew Odhiambo, Matilda Ong’ondi, Sitna Mwanzi, Mercy Gatua, NAOthieno- Abinya

“…Anemia resolved during the first 12 months of therapy while neutropenia and thrombocytopenia resolved within 24–36 months of treatment. …”
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Analisis yuridis terhadap undang-undang no.18 tahun 2012 tentang ketahanan pangan pada keluarga miskin dalam perspektif maqasid syariah by Nadilla Zahra, Ramadani Ramadani

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Cardiometabolic risk factors in the Swedish Werlabs cohort based on self-initiated health screening: cohort profile by Peter Ueda, Kerstin Brismar, Anna Norhammar, Daniel Peter Andersson, Hannah Coudé Adam, Omid Hajimirsadeghi, Lovisa Krantz, Nadia Bandstein Forsberg

“…In an analysis restricted to 621 individuals with recorded blood pressure data between the age of 40 and 70 years and without existing cardiovascular disease, diabetes or kidney disease, 35,4% were classified as high or very high cardiovascular risk according to the 2021 ESC guidelines on cardiovascular disease prevention and with lipid levels that made them eligible for lipid-lowering therapy.Future plans The Werlabs cohort comprises a rather healthy and young population that can provide opportunities for future studies on individuals undergoing self-initiated health examinations and has the potential to impact treatment of cardiometabolic risk factors.…”
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Outcome of Chair-Side Dental Fear Treatment: Long-Term Follow-Up in Public Health Setting by T. Kankaala, T. Määttä, M. Tolvanen, S. Lahti, V. Anttonen

“…A psychological approach including behavioral interventions and cognitive behavioral therapy (BT/CBT) was used for all participants combined with conscious sedation or dental general anesthesia (DGA), if needed. …”
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Textbook outcome in ovarian cancer and its impact on survival: comparative study by Silvia Carbonell-Morote, Alvaro Arjona-Sánchez, Pedro Antonio Cascales-Campos, Alida González-Gil, Gonzalo Gomez-Dueñas, Elena Gil-Gómez, Iban Caravaca-García, Veronica Aranaz, Francisco Javier Lacueva, José Manuel Ramia

“…Inclusion criteria were > 18 years old, with ovarian cancer and peritoneal carcinomatosis, who underwent scheduled surgery after response to neoadjuvant therapy. The criteria to establish TOOC were no major complications, no mortality, non-prolonged stay (p75:10 days), complete cytoreduction (CC-0), and no readmission. …”
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