Preparation, characterisation, and in vitro cancer‐suppression function of RNA nanoparticles carrying miR‐301b‐3p Inhibitor by Junjie Zhao, Niu Niu, Fan Yang, Haitao Liu, Weibo Qi

“…Conclusion Based on RNA self‐assembling, the authors researched the effect of miRNA on DDP sensitivity in LUAD regarding gene regulation. 3WJ‐apt‐miR paves the way for clinical tumour therapy.…”
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Bone marrow transplantation reverses metabolic alterations in multiple sulfatase deficiency: a case series by Nishitha R. Pillai, Ning Liu, Xiyuan Li, Xiqi Li, Rebecca Ahrens-Nicklas, Laura Adang, Julie B. Eisengart, Grace Bronken, Ashish Gupta, Troy C. Lund, Chester B. Whitley, Sarah H. Elsea, Paul J. Orchard

“…Other than symptomatic treatment, no curative therapy exists as of yet for MSD. Eight out of these 17 sulfatases are primarily localized in the lysosome. …”
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Prevalence and factors associated with xerostomia in patients hospitalized due AIDS-related complications by Jhonatan Yukio Naka, Adryano Arana Kamei, Vanessa C. Klamas, Mateus A. Ventura, Marcelo Morato, Rafael Z. Mobile, Antonio A. S. D. Lima

“…Of the total sample, 76% of individuals used antiretroviral therapy and other drugs capable of inducing hypo-salivation and, consequently, xerostomia. …”
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Factors Influencing the Serum Uric Acid in Gout with Cerebral Infarction by Yi Li, Hongyi Yang, Yao Tian, Lihua Duan

“…The data also suggested that uric acid-lowering therapy may need to be strengthened in the young gout+CI patients with a history of smoking.…”
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Emphysema is associated with thoracic vertebral bone attenuation on chest CT scan in HIV-infected individuals. by Alycia Petraglia, Joseph K Leader, Matthew Gingo, Meghan Fitzpatrick, John Ries, Cathy Kessinger, Lorrie Lucht, Danielle Camp, Alison Morris, Jessica Bon

“…<h4>Background</h4>Age-related chronic diseases are prevalent in HIV-infected persons in the antiretroviral therapy (ART) era. Bone mineral density (BMD) loss and emphysema have separately been shown to occur at a younger age and with lesser risk exposure in HIV-infected compared to HIV-uninfected individuals. …”
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Clinical features of pneumatosis intestinalis induced by alpha- glucosidase inhibitor in patients with type 2 diabetes mellitus: a single center retrospective study by Guanlin Wu, Weiheng He, Huimin Rao, Lin Lu, Xinran He, Xuewen Hou

“…Importantly, total bilirubin levels were lower in those with PI who were on acarbose therapy.ConclusionOur findings highlight the need for increased vigilance regarding the potential development of PI in older diabetic patients with cardiovascular conditions following αGI administration. …”
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A Case of Systemic Lupus Erythematosus/Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Overlap Syndrome with Dissociated Pathological and Immunological Findings by Kazuhiko Kato, Tetsuya Kawamura, Risa Terashima, Yukiko Tsuchiya, Yasuhito Takahashi, Kenji Kasai, Takashi Yokoo

“…SLE/AAV OS was suspected, we started immunosuppressant therapy, and subsequently her renal function improved. …”
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New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine by Minghui Zhang, Minghui Zhang, Zongao Wang, Zongao Wang, Shaojun Liu, Shaojun Liu, Yuxuan Li, Yuxuan Li, Yanting Gong, Yanting Gong, Min Liu, Min Liu

“…We discussed the latest directions and current challenges of TRPV1 receptor-targeting therapy for cancer, and summarized the odorous traditional herbs that modulate TRPV1 receptors, with a view to developing anti-tumor drugs targeting TRPV1 receptors in the future.…”
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NAT10 promotes ovarian cancer cell migration, invasion, and stemness via N4-acetylcytidine modification of CAPRIN1 by Yang Song, Min Cheng

“…These findings suggest that NAT10 may be a promising therapy target for OC. Graphical abstract…”
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The ABC of tDCS: Effects of Anodal, Bilateral and Cathodal Montages of Transcranial Direct Current Stimulation in Patients with Stroke—A Pilot Study by A. Fusco, D. De Angelis, G. Morone, L. Maglione, T. Paolucci, M. Bragoni, V. Venturiero

“…Transcranial direct current stimulation (tDCS) is a noninvasive technique that is emerging as a prospective therapy for different neurologic disorders. Previous studies have demonstrated that anodal and cathodal stimulation can improve motor performance in terms of dexterity and manual force. …”
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Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats by Xiaofeng Bai, Xuedi Zhang, Chun Wang, Yao Liu, Xuemei Liu, Yu Fan, Xia Zhang

“…Stem cells from human exfoliated deciduous teeth (SHED) are a candidate source for cell-based therapy. Owing to their neuroprotective and immunomodulatory effects, these neural crest cells have potential roles in mediating chronic pain. …”
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Reversible Manifestations of Hypothyroidism causing Diagnostic Dilemma: A Case Series by Kaushik Hazra, Somnath Maitra, Sunetra Roy, Isha Ghosh

“…It is crucial to identify this hormone deficiency, as replacement with widely available thyroid hormone supplementation can promptly reverse some of the clinical manifestations, thereby aiding in accurate diagnosis and timely management with appropriate therapy.…”
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SequenceCraft: machine learning-based resource for exploratory analysis of RNA-cleaving deoxyribozymes by M. Eremeyeva, Y. Din, N. Shirokii, N. Serov

“…In particular, DNAzymes able to cleave RNA sequences have a huge potential in gene therapy and sequence-specific analytic detection of disease markers. …”
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Generation of deep learning based virtual non-contrast CT using dual-layer dual-energy CT and its application to planning CT for radiotherapy. by Jungye Kim, Jimin Lee, Bitbyeol Kim, Sangwook Kim, Hyeongmin Jin, Seongmoon Jung

“…Furthermore, dose calculations on CE-pCT and VNC-pCT images from patients undergoing volumetric modulated arc therapy for liver and breast cancer treatment showed the clinical relevance of our approach. …”
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The feasibility of using liver function indices and FibroScan in combination to predict the occurrence of anti-tuberculosis drug-induced liver injury in Patients with liver disease by Shaoqiang Wu, Qiaohua Yang, Huai Li, Yongzhong Li

“…The results highlight the importance of baseline liver health assessment and offer promising implications for clinical practice, aiding in individualized risk estimation and therapeutic decision-making for patients with liver disease initiating anti-tuberculosis therapy. Further validation in larger cohorts is warranted to strengthen the predictive model.…”
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From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis by Hafedh Abbassi, Badra Bannour, Sarra Yacoub, Ekram Guerbej, Imen Bannour, Samir Hidar, Moncef Mokni

“…The patient was treated with anti-tubercular therapy for twelve months, resulting in a favorable clinical outcome. …”
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Pulmonary Artery and Pulmonic Valve Vegetations in a Young Pregnant Filipino with Patent Ductus Arteriosus by Valerie R. Ramiro, Jezreel L. Taquiso, Stephanie Martha O. Obillos, Charlene F. Agustin, Jose Donato A. Magno, Eric Oliver D. Sison

“…Therefore, a follow-up of IE after treatment should be guided by the clinical course and response to therapy as well as the echocardiographic morphology of vegetations over time.…”
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Characterization of tumor prognosis and sensitive chemotherapy drugs based on cuproptosis-related gene signature in ovarian cancer by Wei Tan, Fangfang Dai, Qinyu Ci, Zhimin Deng, Hua Liu, Yanxiang Cheng

“…Other cancer cell death processes, such as necroptosis, pyroptosis, and ferroptosis, have been shown to play crucial roles in the therapy and prognosis of ovarian cancer. However, the role of cuproptosis in ovarian cancer remains unclear. …”
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A decade-long overview of adverse events in a tertiary surgical service in South Africa by H Wain, D L Clarke, S Wall

“…Of those, adverse events related to indwelling devices (32.4%), iatrogenic injuries (12.5%) and intravenous therapy administration (12.5%) contributed most. Pathology-related adverse events contributed 21.4% of the total, of which wound sepsis (29.5%), anastomotic leak (15.1%) and nosocomial pneumonia (14.4%) were the most common. …”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion by Ziyao Wang, Zerong Xie, Yu Mou, Ruiman Geng, Chen Chen, Nengwen Ke

“…Analyzing of the role of TIM‐4 in the immune regulation of PDAC can offer novel insights for immune therapy. Methods We analyzed the TIM‐4 expression in tumor specimens from PDAC patients. …”
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