Balancing CIK Cell Cancer Immunotherapy and PPAR Ligands: One Potential Therapeutic Application for CNS Malignancies by Kira Vordermark, JingJing Pu, Amit Sharma, Jarek Maciacyzk, Ingo G. H. Schmidt‐Wolf

“…ABSTRACT Background Cytokine‐induced killer (CIK) cell therapy has proven successful in clinical trials regarding glioblastoma. …”
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

“…Farnesyltransferase inhibitors (FTIs), such as tipifarnib, are being tested in cancer therapy. However, the full impact of FTIs on farnesylation substrates remains poorly understood, thus limiting their use in precision medicine. …”
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Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report by Makoto Isono, Keiichi Ito, Shinsuke Hamada, Masahiro Takahashi, Hidenori Sasa, Hideyuki Shimazaki, Tomohiko Asano

“…Local recurrence and metastasis at the pelvic bone occurred 4 months later; although radiation therapy was performed, she died of the progressive disease.…”
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Peraturan pemerintah, mekanisme akuntabilitas sosial, dan tata kelola: kajian terhadap pemerintah kampung perbatasan by Syaikhul Falah, Juliana Waromi, Septianus Sulistiawan

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Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic by Ziwei Cui, Peng Wang, Weiyue Gao

“…Additionally, the impact of non-mechanical treatments—such as probiotics and laser therapy—on the oral microbiome is discussed, demonstrating their potential in managing microbial dysbiosis. …”
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Nursing Stress and Thought Control in a Multiperspectival Interpretive Phenomenological Analyses from the United Kingdom, United States and Switzerland by Yumna Ali, Syeda Farhana Kazmi

“…Strategies for stress management and thought control include the practice of mindfulness and meditation through mindfulness-based stress reduction courses, mindfulnessbased cognitive therapy courses; and the conduction of mindfulness-based organisational education on a larger scale. …”
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Results of formation of primary and secondary smallintestinal reservoirs at ulcerative colitis by V. N. Kashnikov, S. I. Achkasov, K. V. Bolikhov, O. I. Sushkov, I. V. Nazarov, A. V. Gusev

“…Comparable results of treatment in analyzed groups have been received due to refusal of primary reservoir formation in patients with more severe course of disease and more intensive and long-term steroid therapy.…”
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2023 Indonesian Guidelines for Heart Failure Treatment: Working Group on Heart Failure and Cardiometabolic Diseases, Indonesian Heart Association by Dian Yaniarti Hasanah, MD, Edrian - Zulkarnain, MD, Habibie - Arifianto, MD, Hawani Sasmaya Prameswari, MD, Leonardo Paskah Suciadi, MD, Paskariatne Probo Dewi Yamin, MD, Rarsari Soerarso Pratikno, MD, Siti Elkana Nauli, MD, Vebiona Kartini Prima Putri, MD, Wahyu Aditya Soedarsono, MD, Yuke - Sarastri, MD

“…Guidelines-Directed Medical Therapy (GDMT) with recommended doses is still underutilized in heart failure patients with reduced ejection fraction (HFrEF). …”
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Unveiling antidiabetic and antioxidant activities of biogenically synthesized red fluorescent graphene quantum dots using Bauhinia variegata L. leaves by Pooja Kadyan, Jaya Saini, Parul Singh, Ponnusamy Thillai Arasu, Sudhir Kumar Kataria

“…The findings highlight the multifunctionality of Bauhinia derived GQDs as promising materials for biomedical and environmental applications, offering eco-friendly alternatives for antidiabetic treatments and antioxidant therapy.…”
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Results of a modified Delphi consensus on the optimal testing pathway for oesophago-gastric cancer care in the UK by Philippe Taniere, Manuel Rodriguez-Justo, Naureen Starling, Wasat Mansoor, Thomas Bird, Martin Eatock

“…Given the level of agreement and that the stopping criteria were met, it was decided not to undertake further Delphi rounds.Conclusion The recommendations support the use of a reflex testing approach for human epidermal growth factor receptor 2, programmed death ligand 1 and microsatellite instability high/mismatch repair deficiency in patients diagnosed with OG cancer who are suitable for treatment with targeted therapy.…”
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Applications of MDMA in Modern Medicine - A Literature Review by Wiktoria Podlasiewicz, Paweł Siudziński, Mateusz Łyko, Alicja Skoczylas, Jakub Kurasz, Wojciech Maj, Wiktoria Tomaszewska, Katarzyna Pala, Piotr Dudziak, Anna Nowak, Maria Golińska

“…Despite the highly promising results of MDMA- assisted therapy so far, additional clinical research is crucial to enable this drug to revolutionise future treatment methods. …”
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Autoimmune Hepatitis with Acute Presentation: Clinical, Biochemical, and Histological Features of 126 Patients by Álvaro Urzúa, Carolina Pizarro, Abraham Gajardo, Rafael Poniachik, Claudia Pavez, Máximo Cattaneo, Javier Brahm, Laura Carreño, Jaime Poniachik

“…Although corticosteroid treatment was associated with better outcomes (OR 0.095, p value = 0.013), more severe patients were less likely to receive this therapy. Discussion. In this large cohort of patients with AAIH, clinical characteristics differ from those reported in patients with chronic AIH. …”
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Loxoscelism: Cutaneous and Hematologic Manifestations by Ngan Nguyen, Manjari Pandey

“…Four pts received glucocorticoid therapy for their hemolytic anemia. The use of steroid and intravenous immunoglobulin (IV Ig) did not seem to show a difference in the time of recovery although those who received steroids required less blood transfusion (2.1 units less). …”
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Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk. by Md Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M Nazmul Hoque

“…Antimicrobial efficacy was evaluated through in-vitro and in-vivo studies, alongside in-silico exploration for potential mastitis therapy. We predicted 1,906 genes and 204 SEED sub-systems involved in carbohydrate metabolism and vitamin B complex biosynthesis, with a focus on lactose metabolism in MMBL6. …”
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Rasagiline as Adjunct to Levodopa for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis by Osamu Kano, Hiroshi Tsuda, Ayako Hayashi, Masaki Arai

“…Rasagiline is a selective, irreversible monoamine oxidase type B inhibitor used as monotherapy in early Parkinson’s disease and as an adjunct therapy to levodopa in Parkinson’s disease with motor fluctuations. …”
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Neoadjuvant programmed death ligand-1 with chemotherapy versus chemotherapy alone for limited-stage small-cell lung cancer: a retrospective study by Zhi Yang, Yan-qing Wang, Xiujun Chang

“…We first found that ProGRP is a good the evaluation indicator for neoadjuvant immunotherapy in small cell lung cancer and found that the ProGRP levels decreased significantly in both group after neoadjuvant therapy, and it was more obvious in group I(P=0.003).All Of the 17 patients (100.0%) had R0 resection. …”
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Novel Pt (II) Complexes With Anticancer Activity Against Pancreatic Ductal Adenocarcinoma Cells by Erika Stefàno, Gianluca Rovito, Luca G. Cossa, Federica De Castro, Viviana Vergaro, Asjad Ali, Giulia My, Danilo Migoni, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi

“…However, it did appear to influence the rapid loss of mitochondrial membrane potential (ΔΨM), suggesting that these complexes could potentially be used as mitochondria-targeted lipophilic cations in anticancer therapy.…”
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Corrigendum to “Depletion of ß1,6-N-acetylglucosaminyltransferase reduces E-selectin binding capacity and migratory potential of human gastrointestinal adenocarcinoma cells” [Neopl... by Lisa Staffeldt, Hanna Maar, Julia Beimdiek, Samuel Chambers, Kristoffer Riecken, Mark von Itzstein, Falk FR Buettner, Arun Everest-Dass, Tobias Lange

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Agenesis of Medial Patellofemoral Ligament (MPFL) with Habitual Patellar Dislocation in Adolescent Woman with Cerebral Palsy – A Case Report by Nurul Hidayah, Felix Giovanni Hartono, Bramta Putra Manyakori, Agus Sari Budaya

“…Background: The current treatment for habitual dislocation and nonoperative treatment failure is surgical therapy. Therefore, this study describes chronic patella dislocation's comprehensive evaluation and management in an adolescent woman with cerebral palsy (CP). …”
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Nursing care of an adolescent with hidradenitis suppurativa complicated with bilateral axillary skin ulcers (1例化脓性汗腺炎青少年患者双侧腋窝皮肤溃疡的护理) by WU Xiaokun (吴小堃), YE Xuemei (叶雪梅), PENG Mengmiao (彭梦苗), LAN Yutao (蓝宇涛), LI Haiyan (李海燕)

“…Nurses had work with doctor to control MRSA infection, ensured effective negative stress wound therapy, observed the survival of the flap, provided health education to enhance patients' ability to proactively manage wounds and prevent recurrence, reduced the pain of the patient's wound and prevented the occurrence of mood disorders. …”
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