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16061
Transcriptional Profiling Reveals Kidney Neutrophil Heterogeneity in Both Healthy People and ccRCC Patients
Published 2021-01-01“…Besides, ccRCC neutrophil could resist anticancer immune therapies of ipilimumab and pembrolizumab for their low/no expressions of CTLA-4, PD-1, and PD-L1. …”
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16062
Ankylosing Spondylitis
Published 2021-07-01“…In resistant cases, local or systemic therapy with corticosteroids are recommended. NSAIDs, disease-modifying anti-rheumatic drugs (DMARDs), methotrexate, azathioprine, anti-IL-17A monoclonal antibodies, and TNF-α antagonists are effective treatments for ocular and systemic manifestations of AS. …”
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16063
Patient Management in Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Published 2021-06-01“…Minimising alcohol consumption and smoking is critical. A hepatotropic drug therapy is most essential in moderate fibrotic NAFLD. …”
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16064
Non-pharmaceutical interventions for people living with HIV with cognitive impairment: A scoping review.
Published 2024-01-01“…<h4>Background</h4>Cognitive impairment (CI) in HIV is often of multifactorial causation, and remains a prominent issue in the age of effective combination antiretroviral therapy (cART), affecting approximately 14% of people living with HIV. …”
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16065
ATF4-mediated expression of NOXA is critical for necroptosis driven by glucose deprivation
Published 2025-01-01“…These results provide insights into the regulatory mechanisms underlying Noxa dynamics during GD treatment and highlights its potential as a therapeutic target in cancer therapy and necroptosis-related diseases.…”
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16066
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16067
Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study
Published 2022-06-01“…Ontario drug benefit dispensation records will be used to ascertain PPI exposure during DOAC therapy. The primary outcome is a composite of clinically relevant bleeding, thrombotic events or all-cause death. …”
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16068
Therapeutic Effect of Oral Bisphosphonates on Choroidal Neovascularization in the Human Eye
Published 2010-01-01“…Thirty-six consecutive cases with CNV due to AMD or PM who declined anti-VEGF therapy were recruited. The patients were prescribed 5 mg of oral alendronates daily for 6 months. …”
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16069
Indirect Comparison Showed Survival Benefit from Adjuvant Chemoradiotherapy in Completely Resected Gastric Cancer with D2 Lymphadenectomy
Published 2013-01-01“…Little data on directly comparing chemoradiotherapy with observation has yet been published in the setting of adjuvant therapy for resected gastric cancer who underwent D2 lymphadenectomy. …”
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16070
Comparison of clinicopathological characteristics and prognosis between primary squamous cell carcinoma of the thyroid and squamous cell carcinoma combined with papillary thyroid c...
Published 2025-01-01“…Patients in the SCC-PTC group with more frequent radioactive iodine therapy, surgery, and less frequent radiotherapy than PSCCT. …”
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16071
Risk Factors for Persistent or Recurrent Central Serous Chorioretinopathy
Published 2019-01-01“…These patients may require early photodynamic therapy. Treatment for sleep disorders is strongly recommended. …”
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16072
A comprehensive scoping review of intergenerational dance programmes for cohorts with a generational gap.
Published 2024-01-01“…Exclusion criteria included dance movement therapy or groups with less than one generational gap. …”
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16073
A Disentangled Representation-Based Multimodal Fusion Framework Integrating Pathomics and Radiomics for KRAS Mutation Detection in Colorectal Cancer
Published 2024-09-01“…Kirsten rat sarcoma viral oncogene homolog (namely KRAS) is a key biomarker for prognostic analysis and targeted therapy of colorectal cancer. Recently, the advancement of machine learning, especially deep learning, has greatly promoted the development of KRAS mutation detection from tumor phenotype data, such as pathology slides or radiology images. …”
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16074
Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity
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16075
Biomaterials used in regeneration of salivary gland in three-dimensional culture system -a systematic review
Published 2024-06-01“…Background: Salivary gland dysfunction is caused by various pathological conditions including radiation therapy. Regeneration of the salivary gland components will pave a new path in restoring its function. …”
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16076
Case Report: A rare presentation of rapidly progressive moyamoya disease refractory to unilateral surgical revascularization
Published 2024-08-01“…While the pathophysiology of MMD is unknown, there remain numerous clinical associations including radiation therapy to the brain, inherited genetic syndromes, hematologic disorders, and autoimmune conditions. …”
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16077
An Investigation of Hand Gestures for Controlling Video Games in a Rehabilitation Exergame System
Published 2025-01-01“…However, traditional rehabilitation methods can be expensive and may lack engagement, leading to poor adherence to therapy exercise routines. An <i>exergame</i> system can be a solution to this problem. …”
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16078
Status of the Multidrug Resistance-1 Gene of Plasmodium falciparum in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine as First-Line Treatment fo...
Published 2023-01-01“…Chloroquine (CQ) was widely used in Cameroon for decades, but its declining clinical efficacy due to resistance prompted health authorities in 2004 to resort to artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria. …”
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16079
Metastatic papillary thyroid carcinoma with internal jugular vein tumor thrombus - A case report and review of the literature
Published 2025-01-01“…Postoperatively, the patient received radioactive iodine (I-131) ablation therapy. At the one-year follow-up, imaging studies indicated a recurrence of the disease. …”
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16080
Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages.
Published 2013-01-01“…The Brucella intracellular replicative niche in macrophages and dendritic cells thwarts immune surveillance and complicates both therapy and vaccine development. Currently, host-pathogen interactions supporting Brucella replication are poorly understood. …”
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