Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis by Alina A. Alshevskaya, Julia A. Lopatnikova, Nadezhda S. Shkaruba, Oksana A. Chumasova, Aleksey E. Sizikov, Aleksander V. Karaulov, Vladimir A. Kozlov, Sergey V. Sennikov

“…The objective of this study was to investigate the expression of IL-1β membrane-bound receptors (IL-1R1 and IL-1R2) in terms of the percentage of receptor-positive cells and the number of receptors per cell in different subsets of immune cells in RA patients before and after a course of basic (excluding anticytokine) therapy and in healthy individuals. The resulting data indicate differences in the expression of IL-1β receptors among T cells, B cells, and monocytes in healthy volunteers and in rheumatoid arthritis patients. …”
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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

“…Although increased immune checkpoint expression is generally linked to poor prognosis, tumors with high SOX2 expression exhibited higher responsiveness to immune checkpoint inhibitors, suggesting that targeting SOX2 may improve immune checkpoint therapy efficacy.The study highlights SOX2 as a key factor in cancer prognosis and immune infiltration across multiple tumor types. …”
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Physiological Alterations due to Hepatotoxicity and the Protective Role of Cleome viscosa Linn Seed Extract in Experimental Animals by Addai-Mensah Donkor, Martin Ntiamoah Donkor, Benjamin Ahenkorah, Kwadwo Asante Asare-Konadu, Emmanuel Asiedu, Richard Mosobil

“…For that reason, in the future, oral intake of C. viscosa seed extract as an adjunct natural therapy may be worthwhile to protect against liver failure-mediated inhibitory effects on reproductive function.…”
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Determinan yang mempengaruhi keberlanjutan bisnis toko sembako di Kecamatan Medan Denai by Juni Anggriany, Isnaini Harahap, Aqwa Naser Daulay

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Bicarbonate Within: A Hidden Modulator of Antibiotic Susceptibility by Selvi C. Ersoy, Warren E. Rose, Richard A. Proctor

“…Translationally, β-lactam therapy has proven effective against NaHCO₃-responsive MRSA in both ex vivo simulated endocarditis vegetation (SEV) and in vivo rabbit infective endocarditis (IE) models. …”
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Application and progress of 3D printed biomaterials in osteoporosis by Chenxu Wang, Chenxu Wang, Aiguo Liu, Aiguo Liu, Ziwen Zhao, Ting Ying, Shuang Deng, Zhen Jian, Xu Zhang, Chengqing Yi, Dejian Li

“…Conventional treatments, such as pharmaceutical drugs and hormone replacement therapy, often yield suboptimal results and are frequently associated with side effects. …”
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Assessing the Association between Leptin and Bone Mineral Density in HIV-Infected Men by Madhu N. Rao, Morris Schambelan, Viva W. Tai, Donald I. Abrams, Hootan Khatami, Peter J. Havel, Giorgos Sakkas, Kathleen Mulligan

“…Furthermore, HIV infected individuals on antiretroviral therapy are at increased risk for altered fat distribution, which may impact the relationship between leptin and BMD. …”
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Accuracy of an articulated head-and-neck motion model using deep learning-based instance segmentation of skeletal bones in CT scans for image registration in radiotherapy by Alexandra Walter, Cornelius J. Bauer, Ama Katseena Yawson, Philipp Hoegen-Saßmannshausen, Sebastian Adeberg, Jürgen Debus, Oliver Jäkel, Martin Frank, Kristina Giske

“…Knowing about anatomical deformations in patient images is crucial for adaptive image-guided radiation therapy. Biomechanical models ensure biofidelity in deformable image registration, but manual contouring limits their clinical use. …”
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Autoimmune Polyglandular Syndrome Type 3 with Anorexia by Toshio Kahara, Hitomi Wakakuri, Juri Takatsuji, Iori Motoo, Kosuke R. Shima, Kazuhide Ishikura, Rika Usuda, Yatsugi Noda

“…Extended periods of cobalamin deficiency can cause serious complications such as ataxia and dementia, and these complications may not be reversible if replacement therapy with cobalamin is delayed. Although type 1 diabetes mellitus with coexisting pernicious anemia is very rare in Japan, physicians should consider the possibility of pernicious anemia when patients with diabetes mellitus have cryptogenic anorexia with the finding of significant macrocytosis (MCV > 100 fL).…”
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Informal caregiving and mental health: results from the Belgian health interview survey 2013 and 2018 by Filip Van Droogenbroeck, Bram Spruyt, Pierre Gérain, Laura Van den Borre, Pierre Smith, Robby De Pauw, Sarah Dury

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Fetal Alcohol Syndrome: Impact on Neurodevelopment, Diagnosis, Early Intervention and Motor Disorders in Children under 3 Years by Sabina Adamczyk, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Gabriela Trestka, Urszula Zelik, Jakub Dziewic, Joanna Śnieżna, Wojciech Florczak, Wiktoria Domino, Karol Dzwonnik

“…Intervention strategies, including physical and cognitive therapy, can help mitigate long-term disabilities associated with these conditions. …”
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Mucosa-Associated Lymphoid Tissue Lymphoma of the Larynx by Omar Rizvi, Tyson Nielsen, Shethal Bearelly

“…Following completion of radiation therapy, she had improvement of her sore throat, nausea, dysphagia, dysgeusia, and dry mouth. …”
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The Wilson's disease - etiology, symptoms in various organs, diagnosis, treatment, prognosis by Patryk Graczyk, Paulina Klaudia Kwaśniewska, Anna Wilewska, Kinga Borowiec, Agnieszka Borowiec, Julia Biernikiewicz, Konstanty Alabrudziński, Milena Biernikiewicz, Bartosz Pomirski, Agata Pomirska

“…However, nonadherence to lifelong therapy remains a major hurdle, emphasizing the need for ongoing patient education. …”
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Nursing of a patient with post-stroke constipation treated with moxibustion combined with auricular acupoint pressing based on the brain-gut axis theory (基于脑-肠轴理论艾灸联合耳穴压豆干预1例脑卒中后便秘... by ZHANG Ping (张平), LIU Hua (刘华), YANG Xing (杨星)

“…Based on the brain-gut axis theory, the moxibustion combined with auricular acupoint pressing therapy and individualized nursing interventions were carried out to relieve the abdominal distension and anxiety of the patient. …”
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Whipple’s Disease: Our Own Experience and Review of the Literature by Jan Bureš, Marcela Kopáčová, Tomáš Douda, Jolana Bártová, Jan Tomš, Stanislav Rejchrt, Ilja Tachecí

“…Long-term (up to one year) antibiotic therapy provides a favourable outcome in the vast majority of cases. …”
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Bagaimana perkembangan kurikulum di indonesia?: sebuah tinjauan berbasis meta-analisis terhadap perkembangan kurikulum vokasi di indonesia by Rizkayeni Marta, Hasan Maksum, Waskito Waskito, Ika Parma Dewi, Lativa Mursyida

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Spatial analysis of regency city minimum wage, labor force, regional original income and investment affecting gross regional domestic product in central Java province in 2022 by Darwin Kasidi, Husnul Fitri

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Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation by Matthew R. Lewin, Stephen P. Samuel, David S. Wexler, Philip Bickler, Sakthivel Vaiyapuri, Brett D. Mensh

“…Acetylcholinesterase inhibitors can be therapeutic in neurotoxic envenomations when administered intravenously, but nasally delivered drugs could facilitate prehospital therapy for these patients. We tested the feasibility of this idea in experimentally envenomed mice. …”
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Protective Effects of Chicken Egg Yolk Immunoglobulins (IgYs) against Vibrio vulnificus Infections by Ruizhao Cai, Ning Liu, Penghao Guo, Kang Liao, Mengzhi Li, Junyou Zhu, Shouyi Chen, Lei Chen, Bin Shu, Shaohai Qi

“…These results prove that anti-V. vulnificus IgYs can be markedly effective means for the prophylaxis and the therapy of V. vulnificus infections.…”
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How to Deal with Pulpitis: An Overview of New Approaches by Jakub Fiegler-Rudol, Wojciech Niemczyk, Katarzyna Janik, Anna Zawilska, Małgorzata Kępa, Marta Tanasiewicz

“…<b>Background:</b> Traditional root canal therapy (RCT) effectively removes diseased or necrotic pulp tissue and replaces it with inorganic materials. …”
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