Factors Influencing Postoperative Inpatient Rehabilitation Requirement After Surgical Intervention for Isolated Hip Fracture: A Multicenter Study by Daniel J. Lynch, Andrew Romero, James P. McFadden, Peter Zeblisky, Huazhi Liu, Darwin Ang

“…This cohort had a longer average hospital stay, higher incidence of diabetes, congestive heart failure, chronic renal failure, history of cerebrovascular accident, functionally dependent health status, hypertension, chronic obstructive pulmonary disease, dementia, baseline anticoagulation therapy, and history of myocardial infarction. DVT during hospitalization was encountered more often in patients discharged to rehab. …”
Get full text

Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter by Wolfgang Boecker, Oliver Y. Bernecker, Joseph C. Wu, Xinsheng Zhu, Tomohiro Sawa, Luanda Grazette, Anthony Rosenzweig, Federica del Monte, Ulrich Schmidt, Roger J. Hajjar

“…A major limitation of myocardial gene therapy is the extracardiac transgene expression. …”
Get full text

Sensory substitution and augmentation techniques in cerebral visual impairment: a discussion of lived experiences by Stephanie L. Duesing, Katie Lane-Karnas, Sebastian James Adam Duesing, Mae Lane-Karnas, Nai Y, Arvind Chandna, Arvind Chandna

“…Efforts to improve visual perception ability and understanding of the visual world, both effective and ineffective, were made through traditional, professionally administered vision therapy, self-taught coping strategies, and from intensive arts participation. …”
Get full text

Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature by Gaurang Modi, Irappa Madabhavi, Harsha Panchal, Apurva Patel, Asha Anand, Sonia Parikh, Pritam Jain, Swaroop Revannasiddaiah, Malay Sarkar

“…There was a partial response to decitabine according to RECIST criteria. As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications. …”
Get full text

Parallel-group, randomised, controlled, non-inferiority trial of high-flow nasal cannula versus non-invasive ventilation for emergency patients with acute cardiogenic pulmonary oed... by Apichaya Monsomboon, Onlak Ruangsomboon, Nattakarn Praphruetkit

“…Introduction High-flow nasal cannula (HFNC) is an innovative oxygen-delivering technique, which has been shown to effectively decrease the intubation risk in patients with hypoxaemic respiratory failure of various aetiologies compared with conventional oxygen therapy. Also, it has proved to be non-inferior to non-invasive positive pressure ventilation (NIPPV) in patients with hypoxaemic respiratory failure primarily due to pneumonia. …”
Get full text

BETTER OUTCOME OF HIGH-DOSE CEFTAZIDIME IN HEMATO – ONCOLOGICAL PATIENTS WITH INFECTIONS CAUSED BY EXTENSIVELY DRUG-RESISTANT PSEUDOMONAS AERUGINOSA by Alzbeta Zavrelova, Jakub Radocha, Pavla Paterova, Pavel Zak, Benjamin Visek, Martin Sima

“…More patients in cohort A needed mechanical ventilation and renal replacement therapy, 75% and 50% for cohort A and 27.3% and 9.9% for cohort B, respectively.  …”
Get full text

A retrospective analysis of migraine prophylaxis with anti-CGRP monoclonal antibodies at the hospital of Lithuanian University of Health Sciences Kaunas Clinics by V. Karpavičiūtė, K. Statkevičienė, G. Žemgulytė

“…After treatment, the number of MHDs was significantly reduced in both anti-CGRP mAbs therapy groups (p<0.001). The response to anti-CGRP mAbs was similar between the EM and CM groups. …”
Get full text

Platycodon grandiflorum-derived extracellular vesicles suppress triple-negative breast cancer growth by reversing the immunosuppressive tumor microenvironment and modulating the gu... by Min Yang, Jia Guo, Jinxian Li, Shuyue Wang, Yuan Sun, Ying Liu, Yinghua Peng

“…In contrast, plant-derived extracellular vesicles (PEVs) exhibit promising potential in cancer therapy due to their negligible systemic toxicity, high bioavailability and cost- effectiveness. …”
Get full text

A Chemically Defined Serum-Free Culture System for Spontaneous Human Mesenchymal Stem Cell Spheroid Formation by Yajun Zhao, E. Xiao, Wanqi Lv, Xian Dong, Linhai He, Yixiang Wang, Yi Zhang

“…In summary, we developed a 3D spheroid culture system through TeSR-E8 medium without the involvement of low adhesion conditions and special equipment, which provided a practical and convenient method for spheroid formation of MSCs with great potential for stem cell clinical therapy.…”
Get full text

Repurposing antiviral drugs targeting the PARP-1 and HER2 pathways with multifaceted impacts through integrated network analysis and molecular mechanics by Uma Maheshwari Mugundan, Praveen Sekar, Rajanandh Muhasaparur Ganesan

“…Efavirenz demonstrated effectiveness against both targets, emphasizing its potential and showcasing drug repurposing as a promising strategy in cancer therapy development.…”
Get full text

Inhalation of multiple pen caps causing bronchial foreign bodies: a rare case in an older child by Jia Zhai, Yongsheng Guo, Chunlei Chen, Xuelin Wang, Yifan Wang, Ying-Xue Zou

“…The patient was started on anti-infective therapy to address any underlying infection before proceeding with removal. …”
Get full text

A pre-clinical MRI-guided all-in-one focused ultrasound system for murine brain studies by Tarana Parvez Kaovasia, Sarah Duclos, Dinank Gupta, Kourosh Kalayeh, Mario Fabiilli, Douglas C. Noll, Jonathan Sukovich, Aditya Pandey, Zhen Xu, Timothy L. Hall

“…Abstract This paper describes the design and initial proof-of-concept of a single pre-clinical transcranial focused ultrasound (FUS) system capable of performing histotripsy (mechanical ablation), hyperthermia, blood-brain barrier opening (BBBO), sonodynamic therapy, or neuromodulation in a murine brain. We have termed it the All-in-One FUS system for murine brain studies, which is the first FUS system of its kind. …”
Get full text

Analysis of motivations for treatment of primary open-angle glaucoma by L.A. Zaporozhetc

“…</p> <p> <b>Keywords: </b>primary open-angle glaucoma, motivation, IOP-lowering therapy, optical coherence tomography. </p> <p> <b>For citation:</b> Zaporozhets L.A. …”
Get full text

ACUPRESSURE AND AROMATIC GINGER HERB FOR A MIGRAINE by Mayla Khayra Al ‘Amali, Ario Imandiri, Sukardiman Sukardiman

“…Purpose: Knowing the effect of acupressure and aromatic ginger herbs (Kaempferia galangal Linn.) combination therapy in reducing migraine complaints. Methods: Acupressure at Fengchi point (GB20) 50 times, Taiyang (EX-HN5) 50 times, Sanyinjiao (SP6) 30 times, Taichong (LR3) 50 times and aromatic ginger herbs (Kaempferia galangal Linn.) 15 grams for 28 days. …”
Get full text

Estradiol and progesterone levels in early pregnancy after natural, estradiol + progesterone or gonadotrophin stimulated frozen embryo transfer cycle: a randomised controlled trial... by Nina Freiesleben Mørch, Mette Petri Lauritsen, Pernille Fog Svendsen

“…Introduction Frozen embryo transfer is being increasingly used for assisted reproductive therapy and offers similar pregnancy rates as treatment with fresh embryo transfer. …”
Get full text

A Matching-Adjusted Indirect Comparison of Sonidegib and Vismodegib in Advanced Basal Cell Carcinoma by Dawn Odom, Deirdre Mladsi, Molly Purser, James A. Kaye, Eirini Palaka, Alina Charter, Jo Annah Jensen, Dalila Sellami

“…Vismodegib, the other approved targeted therapy, also was assessed in a single-arm trial (ERIVANCE). …”
Get full text

Imaging pathology in archived cornea with Fuchs’ endothelial corneal dystrophy including tissue reprocessing for volume electron microscopy by Sayo Maeno, Philip N. Lewis, Robert D. Young, Yoshinori Oie, Kohji Nishida, Andrew J. Quantock

“…Intact archived samples can be extremely valuable where, as with FECD, new cell-based methods of therapy now avoid excision of the full cornea thickness and any tissue excised is inferior for study. …”
Get full text

The volatilome – investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC) by Philipp Opitz, Olf Herbarth

“…Methods In this retrospective case-control study urinary VOM of 53 therapy-naive patients with head and neck squamous cell carcinoma (HNSCC) and 82 healthy controls were semi-quantified by headspace solid-phase micro extraction (SPME) gas chromatography (GC) mass spectrometry (MS). …”
Get full text

Evaluation of Drug Use Pattern in Emergency Department of Dilchora Referral Hospital, Dire Dawa, Ethiopia by Kirubel M. Mishore, Nigatu A. Bekele, Tsegaab Y. Yirba, Tsion F. Abone

“…Rationalization of drug therapy in emergency medicine would be useful in managing the broad array of conditions that present for emergency care. …”
Get full text

Myocarditis Concurrent with Sweet Syndrome: A Presentation of Acute Myeloid Leukemia by Christopher G. Burkeen, David Pottinger, Chaitanya Iragavarapu, Reshma Ramlal, Gerhard Hildebrandt

“…Bone marrow biopsy with count recovery after reinduction therapy revealed complete response (CR).…”
Get full text