Upper Gastrointestinal Bleeding as a Debut Form of Groove Pancreatitis: A Diagnostic Challenge by Belén Matías-García, Camilo José Castellón-Pavón, Gustavo Díaz-García, Belén Manso-Abajo, Daniel Hernández-Aceituno, Antonio Hermosín-Peña, Luis Mejías-Sosa, Manuel Durán-Poveda

“…Although some authors recommend a stepwise management with initial conservative therapy, a therapeutic strategy has not yet been established. …”
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Hypokalemic paralysis in an adolescent following dexamethasone and B12 injection: A case report and literature review by Keivan Sahebi, Hassan Foroozand, Mohammad Bahmei, Raziee Taghizadeh, Samane Zare, Soroor Inaloo

“…After potassium replacement therapy, the patient fully recovered and was discharged after five days. …”
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Antimicrobial susceptibility of Helicobacter pylori isolates in Smolensk in 2015-2016 by N. N. Dekhnich, N. V. Ivanchik, R. S. Kozlov, A. V. Alimov, A. V. Lukyanova, O. A. Nagaeva, A. S. Steshits, P. G. Bruk

“…So, clarithromycin-containing regimens are recommended for first-line empirical eradication therapy. Use of levofloxacin is questionable in relation to high levels of resistance H. pylori to levofloxacin. …”
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Immediate Effects of Dynamic Cupping on Shoulder Active Range of Motion of Senior Male Handball Players: A Randomized Controlled Trial by Ricardo Cardoso, Adérito Seixas, Isabel Moreira-Silva, Joana Azevedo, Diogo Duarte

“…They were then randomly divided into two groups: the Intervention Group (IG; n = 40), which received dynamic cupping therapy, and the Control Group (CG; n = 40), which did not receive any intervention. …”
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The Clock Drawing Task reveals executive dysfunction in the dialysis population – an underrecognized and underestimated problem by Piotr Olejnik, Aleksandra Golenia, Oliwia Maciejewska, Ewa Wojtaszek, Paweł Żebrowski, Jolanta Małyszko

“…We also investigated the relationship between cardiovascular risk factors and cognitive test results.Rationale for the study Patients with CKD, including those undergoing renal replacement therapy, are at a higher risk of developing cognitive impairment (CI) than the general population. …”
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Efficacy of Functional Re-Education as a Treatment for Infantile Flexible Flatfoot: Systematic Review by Cristina Molina-García, George Banwell, Francisco Álvarez-Salvago, Andrés Reinoso-Cobo, Clara Pujol-Fuentes, Jose Medina-Luque, Laura Ramos-Petersen

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Dual Reporter Gene Imaging by Jiantu Che, Mikhail Doubrovin, Inna Serganova, Ludmila Ageyeva, Pat Zanzonico, Ronald Blasberg

“…Optical and nuclear imaging of tumors produced from these cell lines provides the opportunity to monitor tumor growth and response to therapy. These studies indicate the potential for a wider application of hNIS reporter imaging and translation into patient studies using radioisotopes that are currently available for human use for both SPECT and PET imaging.…”
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A Case of Small Bowel Obstruction Caused by Bezoars Diagnosed with Double Balloon Enteroscopy by Masayuki Saita, Hiroshi Maekawa, Koichi Sato, Hajime Orita, Mutsumi Sakurada, Tomoaki Ito, Kunihiro Sinjoh, Yoshihiro Komatsu, Shigeo Nohara

“…DBE also appears to be a safe and useful diagnostic tool in patients with SBO, and the findings of DBE influence the strategy of therapy in patients in whom the cause of SBO could not be determined by conventional radiography.…”
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Reconstruction of Nasal Skin Cancer Defects with Local Flaps by A. C. Salgarelli, P. Bellini, A. Multinu, C. Magnoni, M. Francomano, F. Fantini, U. Consolo, S. Seidenari

“…The reconstructive modality of choice will depend largely on the location, size, and depth of the surgical defect. Individualized therapy is the best course, and numerous flaps have been designed to provide coverage of a variety of nasal-specific defects. …”
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Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma by Zhuning Wang, Junqiao Yao, Tengyu Dong, Xing Niu

“…Accordingly, this cuproptosis-relevant lncRNA signature offers an efficient approach to identify and characterize diverse prognosis, genomic alterations, and treatment outcomes in LUAD, thus potentially assisting personalized therapy.…”
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A Comprehensive 10-Year Nationwide Pharmacovigilance Surveillance on Antibacterial Agents in Korea: Data Mining for Signal Detection of Trends and Seriousness of Adverse Events by Seon Hu Mo, Soo Hyeon Lee, Chang-Young Choi, Yongjun Sunwoo, Sooyoung Shin, Yeo Jin Choi

“…The predictors may include age (OR 1.05), the number of concomitant medications (OR 1.44), concomitant proton pump inhibitors (OR 1.46) and non-steroidal anti-inflammatory drugs (OR 1.38) use, and specific antibacterial classes, while multiple antibacterial therapy was associated with lower serious ADE risks. …”
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Circulating Th17, Th22, and Th1 Cells Are Elevated in the Guillain-Barré Syndrome and Downregulated by IVIg Treatments by Shujuan Li, Tao Jin, Hong-Liang Zhang, Hong Yu, Fanhua Meng, Hernan Concha Quezada, Jie Zhu

“…Intravenous immunoglobulin therapy downregulated Th17, and Th22 cells and the plasma levels of IL-17 and IL-22 in GBS patients. …”
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THE EFFECTIVENESS OF THE DECOCTION OF RED BETEL LEAVES (PIPER CROCANTUM) AGAINST THE REDUCED SYMPTOMS OF FLUOR ALBUS IN ADOLESCENT GIRLS by Rosa Purwanti, Rini Hayu Lestari, Niken Grah Prihartanti

“…Conclusion: The results this study indicated a decrease in symptoms of vaginal discharge after the use of red betel leaf decoction and recommended it to be used as a form of non-pharmacological therapy or traditional medicine in reducing fluor albus symptoms in adolescent girls.…”
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Paroxysmal Laryngospasm: A Rare Condition That Respiratory Physicians Must Distinguish from Other Diseases with a Chief Complaint of Dyspnea by Yu Bai, Xi-Rui Jing, Yun Xia, Xiao-Nan Tao

“…Paroxysmal laryngospasm is a rare laryngeal disease that generally occurs secondary to gastroesophageal reflux disease (GERD), and antireflux therapy is frequently effective for its treatment. …”
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The expression of lumican, tight junction protein 1, connective tissue growth factor, superoxide dismutase 1 in corneal tissues in graft disease by G.R. Semak, T.A. Letkovskaya, V.A. Zakharava, I.Yu. Zherko

“…An increase in the expression coefficient and the intensity index of lumican expression was revealed during therapy. During treatment with an injectable form of 1% low molecular weight sodium hyaluronate, normalization of the expression coefficient of lumican and connective tissue growth factor in the corneal stroma was noted. …”
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Umbilical Cord Mesenchymal Stem Cells Overexpressing Heme Oxygenase-1 Promotes Symptoms Recovery in Cystitis Rats by Alleviating Neuroinflammation by Qiongqiong Gao, Zhentao Gao, Minzhi Su, Yong Huang, Chi Zhang, Cuiping Li, Hailun Zhan, Bolong Liu, Xiangfu Zhou

“…Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously reduces the patient’s quality of life, yet current therapies only provide partial relief. In the spinal dorsal horn (SDH), neuroinflammation plays a pivotal role in the development of IC. …”
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Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment by Liu Y, Si L, Jiang Y, Jiang S, Zhang X, Li S, Chen J, Hu J

“…Yunheng Liu,1,* Longqing Si,1,* Yuxuan Jiang,1,* Shaojing Jiang,2 Xiaokang Zhang,1 Song Li,1 Jing Chen,1 Jinghui Hu2 1School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China; 2Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Chen, School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email chenjingbyyxy@163.com Jinghui Hu, Yantai Engineering Research Center for Digital Technology of Stomatology, Characteristic Laboratories of Colleges and Universities in Shandong Province for Digital Stomatology, Institute of Stomatology, Binzhou Medical University, Yantai, 264003, People’s Republic of China, Email bykfhjh@163.comAbstract: The metabolic activity of tumor cells leads to the acidification of the surrounding microenvironment, which provides new strategies for the application of nanotechnology in cancer therapy. Researchers have developed various types of pH-responsive nanomaterials based on the tumor acidic microenvironment. …”
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Asymptomatic lung abscess of aspergillus in a female without previous lung diseases or immunocompromise: a case report by Hanxue Xiang, Ling Zhang, Liu Yang, Miaotian Cai, Yingmin Ma, Yulin Zhang

“…Ultimately, the catheterization and drainage of the lung abscess and 6 months of antifungal therapy with standard dose of voriconazole brought the woman a favorable outcome. …”
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Clinical Analysis of Four Patients with Schimke Immuno-Osseous Dysplasia and a Literature Review by HAN Lingli, DONG Yajuan, SUN Bijun, WANG Wenjie, ZHOU Qinhua, LIU Luyao, HOU Jia, WANG Xiaochuan, SUN Jinqiao

“…The treatment for the four patients was mainly by symptomatic supportive therapy and on prevention and delay of renal failure disease.ConclusionsThe patients with SIOD have different onset symptoms and progression of the disease.The treatment has not yet completely cured the disease. …”
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Effect of Electric Fields on the Mechanical Mechanism of Regorafenib–VEGFR2 Interaction to Enhance Inhibition of Hepatocellular Carcinoma by Yichen Tian, Fenghui Liao, Heng Sun, Yongrong Lei, Yuna Fu, Feng Xia, Jianhua Wang

“…The interaction between molecular targeted therapy drugs and target proteins is crucial with regard to the drugs’ anti-tumor effects. …”
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