Innate Immune Response of Human Embryonic Stem Cell-Derived Fibroblasts and Mesenchymal Stem Cells to Periodontopathogens by Gopu Sriram, Vaishali Prakash Natu, Intekhab Islam, Xin Fu, Chaminda Jayampath Seneviratne, Kai Soo Tan, Tong Cao

“…Recently, the potential application of multipotent stem cells and pluripotent stem cells including human embryonic stem cells (hESCs) in periodontal regenerative therapy has been proposed. However, little is known about the impact of periodontopathogens on hESC-derived progenies. …”
Get full text

Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Neuropathy via Wnt Signaling Pathway by Songsong Pan, Sushant S. Hada, Yang Liu, Chao Hu, Mengdie Zhou, Shaoqiu Zheng, Minjie Xu, Changsheng Shi, Shiwu Yin, Xiaoyun Xie

Get full text

Prevalence Rates and an Evaluation of Reported Risk Factors for Osteonecrosis (Avascular Necrosis) in Crohn’s Disease by Hugh J Freeman, Katy J Freeman

“…In this series, risk of osteonecrosis could not be attributed to corticosteroid use, parenteral nutrition or both forms of therapy administered together. Small intestinal resection with loss of small intestinal absorptive area was not a risk factor for the development of osteonecrosis. …”
Get full text

Therapeutic Potential of Liraglutide for Diabetes–Periodontitis Comorbidity: Killing Two Birds with One Stone by Man Yang, Yunqing Pang, Minyu Pei, Yuanyuan Li, Xuemin Yuan, Rongbing Tang, Jing Wang

“…Those indicate that LIRA may be used as a potential medicine for the adjunctive therapy of diabetes-periodontitis comorbidity.…”
Get full text

Inflammatory Cytokine Pattern Is Sex-Dependent in Mouse Cutaneous Melanoma Experimental Model by Mihaela Surcel, Carolina Constantin, Constantin Caruntu, Sabina Zurac, Monica Neagu

“…Clinical parameters and serum cytokines were followed during tumor evolution and during DTIC therapy. Cytokine/chemokine pattern was assessed using xMAP technology and the following molecules were quantified: interleukins (IL)-1-beta, IL-6, IL-10, IL-12 (p70), interferon (IFN)-gamma, granulocyte macrophage colony-stimulating factor (GM-CSF), tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, monocyte chemoattractant protein (MCP-1), and keratinocyte-derived chemokine (KC). …”
Get full text

Central projections of nociceptive input originating from the low back and limb muscle in rats by Ulrich Hoheisel, Rolf-Detlef Treede, Siegfried Mense, Toru Taguchi

Get full text

Sebuah Kajian Literatur Tentang Pengalaman Pasien Kanker Dalam Menghadapi Pandemi Covid-19 by Made Satya Nugraha Gautama, Surya Wahyuni, Muflihul Huda, Istiqomah Nur Khasanah, Ulfa Hikmawati, Slamet Aminanto, Stefany Putri Sahureka, Orin Juliastuty Terawati Rizal

“…The COVID-19 pandemic provides cancer patients with experiences in decision making and undergoing therapy and has a positive and negative impact on cancer patients and caregivers. …”
Get full text

Enhancement of in vitro antitumour activity of epirubicin in HER2+ breast cancer cells using immunoliposome formulation by Farnaz Khaleseh, Abbas Hemmati Azandaryani, Fatemeh Fathian Kolahkaj, Mozafar Khazaei, Katayoun Derakhshandeh

“…In conclusion, these data show that the targeted delivery of EPI to breast cancer cells can be achieved by EPI‐Lipo‐mAb in vitro, and this strategy could be used for breast cancer therapy with further studies.…”
Get full text

Efficacy of 0.5% Levofloxacin and 5.0% Povidone-Iodine Eyedrops in Reducing Conjunctival Bacterial Flora: Metagenomic Analysis by Caixia Fan, Baoxia Yang, Yusen Huang

“…A total of 2.4 × 106 high-quality sequencing reads were generated from 93 conjunctival samples obtained from 31 eyes scheduled for cataract surgery before prophylactic therapy (group 1), after administration of 0.5% levofloxacin eyedrops into the conjunctival sac 8 times before surgery (group 2), and at 3 minutes after instillation of 5.0% PVI solution in the conjunctival sac (group 3) followed by surgery irrigation. …”
Get full text

Akinetopsia: a systematic review on visual motion blindness by Johanna L. Browne, Lydia Krabbendam, Jan Dirk Blom, Jan Dirk Blom, Jan Dirk Blom

“…Treatments were mostly successful when they were aimed at the underlying condition, while cases due to organic lesions tended to be therapy-resistant. Although individual reports confirm that akinetopsia may have detrimental effects on people’s lives, data were insufficient for a proper analysis of such experiential aspects.ConclusionPhenomenologically, pathophysiologically, and etiologically, akinetopsia is more heterogeneous than previously thought. …”
Get full text

Herbaspirillum Infection in Humans: A Case Report and Review of Literature by Rashmi Dhital, Anish Paudel, Nidrit Bohra, Ann K. Shin

“…With the institution of appropriate antimicrobial therapy, the outcomes seem mostly favorable.…”
Get full text

C/EBPβ Regulates HIF-1α-Driven Invasion of Non-Small-Cell Lung Cancer Cells by Seung Hee Seo, Ji Hae Lee, Eun Kyung Choi, Seung Bae Rho, Kyungsil Yoon

“…Hypoxia, a feature of solid tumors, plays a role in cancer progression by inducing resistance to therapy and accelerating metastasis. Here, we report that CCAAT/enhancer-binding protein beta (C/EBPβ) transcriptionally regulates <i>hypoxia-inducible factor 1 subunit alpha</i> (<i>HIF1A</i>) and thus promotes migration and invasion of non-small-cell lung cancer (NSCLC) cells under hypoxic conditions. …”
Get full text

Factors associated with knowledge and practice regarding oxygen administration: A cross-sectional study among registered nurses working in wards and ICUs at Muhimbili National Hosp... by Magdalena S Kimario, Joel Seme Ambikile, Masunga K Iseselo

“…<h4>Background</h4>Oxygen is a vital therapy approved by WHO, crucial for critically ill patients as a supplemental treatment. …”
Get full text

Peran perilaku pengelolaan keuangan sebagai mediator dalam meningkatkan kinerja keuangan UMKM di kota Medan by Rapat Piter Sony Hutauruk, Rika Surianto Zalukhu, Daniel Collyn, Suci Etri Jayanti, Sri Winda Hardiyanti Damanik

Get full text

Long-Pulse Gastric Electrical Stimulation Repairs Interstitial Cells of Cajal and Smooth Muscle Cells in the Gastric Antrum of Diabetic Rats by Yan Chen, Hongcai Wang, Hai Li, Shi Liu

“…Gastric electrical stimulation (GES) is an efficient therapy for gastric motility disorders, but the mechanisms of GES require clarification. …”
Get full text

Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: 131I-antiAFPMcAb-GCV-BSA-NPs by Mei Lin, Junxing Huang, Dongsheng Zhang, Xingmao Jiang, Jia Zhang, Hong Yu, Yanhong Xiao, Yujuan Shi, Ting Guo

“…Due to good drug-loading, high encapsulation ratio, and highly selective affinity for AFP-positive tumors, the 131I-antiAFPMcAb-GCV-BSA-NPs are promising for further effective radiation-gene therapy of hepatoma.…”
Get full text

New Prospects of Cytoprotection in the Treatment and Prevention of Gastric and Intestinal Diseases (Resolution of an Expert Council and Literature Review) by A. I. Martynov, A. A. Sheptulin, I. V. Mayev, A. N. Kazyulin, A. Ye. Karateev, A. V. Melekhov, L. K. Pal’gova, K. L. Raikhel’son

“…In the treatment of gastroesophageal reflux disease, Rebamipide is recommended for patients refractory to therapy with proton pump inhibitors (PPIs) and for those with non-acid reflux. …”
Get full text

Computation Simulation Research of Bushen Zhuangjin Decoction on Multi-target Effects in Delaying Cataplasia of Articular Cartilage by Chunsong ZHENG, Xiaojie XU, Suixin HUANG, Hongzhi YE

“…Furthermore, the compounds in BSZJD work mainly by ways of promiscuous drug in the therapy of OA. This comes up an explanation about BSZJD therapeutical effect for OA based on the theory of"treatment for flaccidity aims at the origin". …”
Get full text

Nursing of integrated Traditional Chinese and western medicine for a patient with diabetic foot ulcer (1例糖尿病右足溃疡患者的中西医结合护理体会) by LUO Yanbin (罗艳彬), GAO Dongqing (高冬青), KOU Lin (寇琳), CUI Xin (崔欣)

“…According to the different stage if wound healing, the Traditional Chinese Medicine external application therapy by syndrome differentiation was carried out to improve the debridement effect, help healthy tissue grow and minimize scarring. …”
Get full text

Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report by Dan E. Wilson, Tashina Van Vlack, Brendin P. Schievink, Eric B. Doak, Jason S. Shane, Elizabeth Dean

Get full text