The Clinical Manifestation Variety and Management Choice of Meckel’s Diverticulum with Complication: A Single Center Experience by Tingliang Fu, Xiaoliang Xu, Lei Geng, Yanli Huang, Guojian Ding, Hong Ji

“…Two other cases received nonoperative therapy and went to other hospitals to receive surgical management. …”
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Exosomal miRNAs involvement in pathogenesis, diagnosis, and treatment of rheumatoid arthritis by Mahvash Sadeghi, Jalil Tavakol Afshari, Afsane Fadaee, Mohammadreza Dashti, Fatemeh Kheradmand, Sajad Dehnavi, Mojgan Mohammadi

“…It highlighted present situation and future perspective of using exosomal miRNAs as biomarkers and a specific gene therapy approach for RA treatment.…”
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Safety and Efficacy of Bivalirudin versus Unfractionated Heparin Monotherapy in Patients with CAD and DM Undergoing PCI: A Retrospective Observational Study by Jing Li, Sanbao Chen, Sicong Ma, Mingque Yang, Zizhao Qi, Kun Na, Miaohan Qiu, Yi Li, Yaling Han

“…A total of 3890 diabetic patients receiving PCI in the General Hospital of Northern Theater Command were divided into the bivalirudin group (n=869) and the UFH group (n=3021) according to different anticoagulant therapy regimens. Indication for PCI was in accordance with current guidelines including national cardiovascular data registry. …”
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Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease by Ryan Jalleh, Gopal Basu, Richard Le Leu, Shilpanjali Jesudason

“…Eight patients (52-85 years of age) with stage 4-5 CKD developed clinically significant hypocalcaemia (corrected calcium 1.45±0.21mmol/L) following denosumab therapy for osteoporosis. Seven of the eight patients required inpatient management with three patients requiring intravenous calcium replacement and cardiac monitoring in a high dependency unit. …”
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Bacteriophage LDT325 enhances Pseudomonas syringae tolerance by improving antioxidant defense in tea plant [Camellia sinensis (L.) O. Kuntze] by Li Liu, Anqi Huang, Hua Zhang, Yubao Li, Lei Wang, Lei Wang

“…In the present study, we determined the effect of bacteriophage therapy on physiological and biochemical parameters of tea leaves. …”
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Myoxinol (Hydrolyzed Hibiscus esculentus Extract) in the Cure of Chronic Anal Fissure: Early Clinical and Functional Outcomes by Adolfo Renzi, Antonio Brillantino, Giandomenico Di Sarno, Francesco D’Aniello, Stefania Ziccardi, Fiorella Paladino, Francesca Iacobellis

“…Among all patients with CAF observed during the study period, 31 subjects met the inclusion criteria and underwent medical therapy with Myoxinol 3% ointment every 12 hours for 6 weeks. …”
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The Protective Effect of Naringin against Bleomycin-Induced Pulmonary Fibrosis in Wistar Rats by Nergiz H. Turgut, Haki Kara, Sahende Elagoz, Koksal Deveci, Huseyin Gungor, Emre Arslanbas

“…These results show that naringin has the potential of reducing the toxic effects of bleomycin and may provide supportive therapy for conventional treatment methods for idiopathic pulmonary fibrosis.…”
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Phylogenetic analysis of dermatophytes isolated from small domestic animals by A. M. Smagulova, E. V. Kukhar, T. I. Glotova, A. G. Glotov

“…The identification of the agent’s species has a great epidemiological significance and is essential for effective therapy. The aim of the study is the identification and phylogenetic analysis of dermatophytes isolated from dogs and cats in the Republic of Kazakhstan and the Russian Federation by means of molecular techniques. …”
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Goal-Oriented Respiratory Management for Critically Ill Patients with Acute Respiratory Distress Syndrome by Carmen Sílvia Valente Barbas, Gustavo Faissol Janot Matos, Marcelo Britto Passos Amato, Carlos Roberto Ribeiro Carvalho

“…Revaluation of ARDS patients on the third day of evolution (Sequential Organ Failure Assessment (SOFA), biomarkers and response to infection therapy) allows changes in the initial treatment plans and can help decrease ARDS mortality.…”
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Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI by Paul J. Akhenblit PhD, Neale T. Hanke PhD, Alexander Gill BS, Daniel O. Persky MD, Christine M. Howison MS, Mark D. Pagel PhD, Amanda F. Baker PharmD, PhD

“…Therefore, this study is a strong example that acidoCEST MRI can be used to measure tumor pHe that may serve as a marker for therapeutic efficacy of anticancer therapies.…”
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Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC by Yujie Hao, Mingchen Li, Wenxu Liu, Zhenyi Ma, Zhe Liu, Zhe Liu, Zhe Liu

“…IntroductionSmall cell lung cancer (SCLC) is characterized by significant heterogeneity and plasticity, contributing to its aggressive progression and therapy resistance. Autophagy, a conserved cellular process, is implicated in many cancers, but its role in SCLC remains unclear.MethodsUsing a genetically engineered mouse model (Rb1fl/fl; Trp53fl/fl; GFP-LC3-RFP-LC3△G), we tracked autophagic flux in vivo to investigate its effects on SCLC biology. …”
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Design and Mechanism Study of 6c, a Novel Artesunate Derivatives, for Anti-Hepatocellular Carcinoma by Xiong SS

“…Molecular docking shows the binding of 6c compound to oncogenic vascular endothelial growth factor receptor 2 (VEGFR-2) and Transferrin receptor protein 1 (TFR1) that are overexpressed in malignant epithelial tumors.Conclusion: Taken together, our identification of the promising compound 6c may hold developmental potential for therapy of hepatocellular carcinoma. Keywords: hepatocellular carcinoma, artesunate, phenoxy-pyridine, hybridization, reactive oxygen species, apoptosis, docking…”
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Predicting pain and its association with mortality in patients with stroke by Adam Viktorisson, Aref Haj Hashem, Katharina S Sunnerhagen, Tamar Abzhandadze

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Human Development from Concept "Soft Skills" Communication by Emilawati Binti Othman, Masfizaizan Binti Manaf

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Following Spinal Cord Injury Transected Reticulospinal Tract Axons Develop New Collateral Inputs to Spinal Interneurons in Parallel with Locomotor Recovery by Zacnicte May, Keith K. Fenrich, Julia Dahlby, Nicholas J. Batty, Abel Torres-Espín, Karim Fouad

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Genetics and pathophysiology of low-renin arterial hypertension by A. L. Markel

“…The discovery of some types of arterial hypertension with known mechanisms of their development is of paramount importance for medicine, as it allows for targeted efective therapy and in some cases for achieving a complete cure. …”
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Application of Traditional Chinese Medicine soaking-bath technique for a patient with chronic renal failure of spleen-kidney Yang deficiency type (中药泡洗技术在1例脾肾阳虚型慢性肾衰竭患者中的应用)... by WU Chunli (吴春丽), TANG Ling (唐玲), DENG Jianhua (邓建华)

“…Based on the comprehensive nursing assessment and basic care, the TCM soaking-bath therapy is effective in relief of fatigue and swelling symptom of the patient with chronic renal failure. …”
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Dramatic response of advanced pulmonary sarcomatoid carcinoma to tislelizumab combined with anlotinib: a case report by Ranran Li, Xiliang Di, Yuan Li, Hao Li, Chonghua Liu

“…This case illustrates the efficacy and safety of combining antitumor immunotherapy with anlotinib, a targeted anti-angiogenic therapy.…”
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Rothia mucilaginosa Meningitis in a Child with Myelodysplastic Syndromes by Fumihiro Ochi, Ryota Nakamura, Reiji Miyawaki, Kyoko Moritani, Shinobu Murakami, Hisamichi Tauchi

“…The patient was treated with intravenous antimicrobial therapy due to meropenem for 43 days because he had febrile neutropenia. …”
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Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease by Abdul-Wahab M. Al-Saqladi, Dikra M. Maddi, Aida H. Al-Sadeeq

“…A retrospective, descriptive study of all children (≤16 years) with SCD who received blood transfusion therapy during their hospital admissions in the pediatric department at Al-Sadaqa Teaching Hospital in Aden, Yemen, for a period of one year. …”
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