Elotuzumab Enhances CD16-Independent NK Cell-Mediated Cytotoxicity against Myeloma Cells by Upregulating Several NK Cell-Enhancing Genes by Yan-Hua Wang, Shotaro Hagiwara, Hiroshi Kazama, Yuki Iizuka, Norina Tanaka, Junji Tanaka

“…Multiple myeloma (MM) is an intractable hematological malignancy caused by abnormalities in plasma cells. Combination therapy using antibodies and natural killer (NK) effectors, which are innate immune cells with safe and potent antitumor activity, is a promising approach for cancer immunotherapy and can enhance antitumor effects. …”
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Concurrent presentation of proliferative glomerulonephritis with monoclonal immunoglobulin deposits and light chain proximal tubulopathy: a case report and review of the literature by Jingdong Zhang, Yang Liu, Fengyan Jin, Jia Li, Hui Wang, Fuzhe Ma, Ye Jia, Jinyu Yu, Shan Wu, Shaojie Fu, Zhonggao Xu, Hao Wu

“…This case emphasizes the critical role of renal biopsy in the diagnosis, particularly in the absence of detectable monoclonal proteins, and demonstrates the efficacy of targeted therapy in managing such complex renal pathologies. …”
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A Rare Cause of Acute Kidney Injury: Primary Renal Lymphoma in a Patient with Human Immunodeficiency Virus by Ruslinda Mustafar, Lydia Kamaruzaman, Beh Hui Chien, Azyani Yahaya, Noor’Ain Mohd Nasir, Rozita Mohd, Rizna Cader, Kong Wei Yen

“…A 37-year-old gentleman with underlying human immunodeficiency virus (HIV) disease was on combined antiretroviral therapy since diagnosis. He presented to our center with uremic symptoms and gross hematuria. …”
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The application of restorative justice as a settlement of domestic syiqaq in QS. An-Nisa verses 34 and 34 according to the view of wahbah az-zuhaili in the book of tafsir al-munir by Khairatun Hisan, Ahmad Zuhri, Nur Aisah Simamora, Mardian Idris Harahap

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How much conversation content is actually social: human conversational behaviour revisited by Anna Szala, Sławomir Wacewicz, Marek Placiński, Aleksandra Ewa Poniewierska, Arkadiusz Schmeichel, Michal Mikolaj Stefanczyk, Przemysław Żywiczyński, Robin I.M. Dunbar

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Pregnancy outcomes in patients with psoriasis, psoriatic arthritis, or axial spondyloarthritis receiving ixekizumab by A. Egeberg, L. Iversen, A. B. Kimball, S. Kelly, E. Grace, H. Patel, W. Xu, G. Gallo, E. Riedl, S. R. Feldman

“…No congenital malformations resulting from maternal exposure were reported in clinical trials: one case, not causally related to ixekizumab therapy, was recorded in the post-marketing setting.Conclusions This integrated safety analysis provides relevant information for clinicians treating patients with psoriasis, PsA, or axSpA with ixekizumab. …”
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Influence of age on voice quality after transoral CO2 laser microsurgery by Jerome R. Lechien, Stephane Hans, Lise Crevier-Buchman

“…Methods Patients treated by type I to VI TLM and post-operative speech therapy were prospectively recruited from our hospital. …”
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Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection by Byoung Wook Bang, Jin Seok Park, Hyung Kil Kim, Yong Woon Shin, Kye Sook Kwon, Joon Mee Kim

“…Considering the clinical efficacy, technical difficulty, and procedure time, the ESMR-L method should be considered as the first-line therapy for the small rectal NET (≤10 mm). ESD should be left as a second-line treatment for the fibrotic lesion which could not be removed using the ESMR-L method.…”
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Case report: Rituximab combined with plasma exchange treatment for systemic lupus erythematosus complicated with thrombotic microangiopathy and non-cirrhotic portal hypertension by Jinmei Huang, Wei Fan, Xuyan Chen, Shufan Wu, Zhigao Dong, Yi Zhang, Yiwan Lin, Pingping Xiao

“…Initial treatment with high-dose methylprednisolone, immunoglobulin shock therapy, and tacrolimus (1 mg, twice daily) improved her symptoms and laboratory indicators. …”
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EBV-associated lymphoadenopathy in a child by H.B. Mateiko, U.A. Hlushko, T.V. Nesterova, L.V. Antoniuk, N.B. Horbal

“…It is recommended to involve a multidisciplinary team to prescribe appropriate antiviral therapy, regularly monitor the clinical course, dynamics of laboratory and immunological indicators. …”
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PREDISPOSITION FACTORS ANALYSIS FOR FOURNIER'S GANGRENE DEFECTS CLOSURE COMPLICATION by Bayu Fasi Bermani, Sitti Rizaliyana, Ira Handriani

“…All patients received broad-spectrum antibiotic therapy, and extensive surgical excision. This study found that diabetes mellitus and uncontrolled patient blood sugar levels, statistically there is no effect on failure of defect closure in Fournier gangrene patients, but clinically, the relative risk value shows that blood glucose levels have a risk factor of 6 times. increasing the incidence of failure to close the Fournier gangrene defect. …”
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Pediatric Sickle Cell Disease in Sudan: Complications and Management by Meysaa Talha, Bashier Osman, Safa Abdalla, Hind Mirghani, Iman Abdoon

“…The SCD treatment protocol in Gaafar Ibnauf Children’s Hospital, involving preventive and symptomatic therapy, is consistent with the internationally implemented protocols for SCD management. …”
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Assessment of Opuntia ficus-indica supplementation on enhancing antioxidant levels by Rahela Zaman, Eugenie Sin Sing Tan, Normina Ahmad Bustami, Farahnaz Amini, Marjan Sadat Seghayat, Yu Bin Ho, Chung Keat Tan

“…These findings suggest its potential as an adjuvant therapy for managing chronic conditions associated with oxidative stress.…”
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Improving the perceived contribution of sustainable tourism through the residents’ empowerment and support for tourism development: A different age group context by Lorena Bašan, Ivana Perušina, Marija Ham

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The impact of binaural auralizations on sound source localization and social presence in audiovisual virtual reality: converging evidence from placement and eye-tracking paradigms★... by Roßkopf Sarah, Kroczek Leon O.H., Stärz Felix, Blau Matthias, Van de Par Steven, Mühlberger Andreas

“…Since social presence and subjective realism are strongly correlated, the implementation of plausible binaural auralizations is suggested for VR settings where high levels of (social) presence are relevant (e.g. multiuser interaction, VR exposure therapy).…”
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RSL3 induces ferroptosis by activating the NF-κB signalling pathway to enhance the chemosensitivity of triple-negative breast cancer cells to paclitaxel by Jialin Yuan, Cong Liu, Chengwei Jiang, Ning Liu, Zhaoying Yang, Hua Xing

“…Through transcriptome sequencing, a series of differentially expressed genes were identified, in which the expression of cytokines, such as CXCLs, was significantly increased in the treatment group, and the effect of combination therapy on TNBC was enriched mainly in the NFκB signalling pathway. …”
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MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma by Changsheng Zhou, Jia Liu, Xudong Hu, Lu Lu, Juan Hou, Jian Wang, Liqun Jiang, Shuangshuang Huang, Yu Lin, Luyao Liu, Lingling Cui, Yiqian Liu, Yufeng Huang

“…In summary, our study demonstrates the importance of the nonmetabolic function of MVK in modifying the immunological milieu and provides new targets for lung adenocarcinoma therapy.…”
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Effectiveness of solution-focused brief counseling to increase achievement motivation of bullying victims by Bambang Dibyo Wiyono, Wiryo Nuryono, Muhamad Afifuddin Ghozali, Olusegun Fatai Adebowale, Akmal Nasri Kamal, Aulia Ramadhani Putri

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Outcome of Late Presentation of Posterior Urethral Valves in a Resource-Limited Economy: Challenges in Management by Odutola Israel Odetunde, Oluwatoyin Arinola Odetunde, Adesoji Oludotun Ademuyiwa, Henrietta Uche Okafor, Uchenna Ekwochi, Jonathan Chukwuemeka Azubuike, Nene Elsie Obianyo

“…Delayed presentation of patients with posterior urethral valve with complications like severe urosepsis, uremia, and anemia are seen in our setting. Renal replacement therapy which should have been offered to these patients is not readily available for children in our country. …”
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Current Status of Canine Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Veterinary Medicine by Tania Sultana, Soojung Lee, Hun-Young Yoon, Jeong Ik Lee

“…Stem cell therapy has prompted the expansion of veterinary medicine both experimentally and clinically, with the potential to contribute to contemporary treatment strategies for various diseases and conditions for which limited or no therapeutic options are presently available. …”
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