A hybrid framework for colorectal cancer detection and U-Net segmentation using polynetDWTCADx by Akella S Narasimha Raju, K Venkatesh, Makineedi Rajababu, Ranjith Kumar Gatla, Marwa M. Eid, Enas Ali, Nataliia Titova, Ahmed B. Abou Sharaf

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Cardiac magnetic resonance imaging in repaired tetralogy of Fallot: A longitudinal midterm follow-up study. by Golnaz Houshmand, Rahem Rahmati, Elahe Meftah, Fatemeh Zarimeidani, Mohammadrafi Khorgami, Seyyed Mojtaba Ghorashi, Amir Fazeli, Negar Omidi, Sedigheh Saedi, Marzieh Motevalli, Majid Maleki, Hamidreza Pouraliakbar

“…<h4>Conclusion</h4>Myocardial strain and ventriculoarterial coupling parameters could underscore personalized-approached therapy and follow-up to improve outcomes.…”
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Interventional Treatment of Abdominal Compartment Syndrome during Severe Acute Pancreatitis: Current Status and Historical Perspective by Dejan V. Radenkovic, Colin D. Johnson, Natasa Milic, Pavle Gregoric, Nenad Ivancevic, Mihailo Bezmarevic, Dragoljub Bilanovic, Vladimir Cijan, Andrija Antic, Djordje Bajec

“…This review will focus on interventional treatment of this serious condition. First line therapy is conservative treatment aiming to decrease IAP and to restore organ dysfunction. …”
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Towards a new spatial representation of bone remodeling by Jason M. Graham, Bruce P. Ayati, Prem S. Ramakrishnan, James A. Martin

“…Computational and mathematical modeling can aid in therapy and treatment as well as understanding fundamental biology. …”
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Efficacy of dupilumab with concomitant topical calcineurin inhibitors treatment for preschool children with atopic dermatitis: a retrospective cohort study by Wu Liming, Kamran Ali

“…We present a cohort study describing the efficacy and safety of dupilumab combined with topical calcineurin inhibitors (TCI) in children with moderate-to-severe atopic dermatitis under the age of 6 years.Methods A retrospective cohort study was conducted at a single center to analyze the use of dupilumab in combination with topical calcineurin inhibitors (TCI) in children aged 6 years and under moderate-to-severe AD that was inadequately controlled with topical therapy.Results Overall, 23 preschool children (mean [SD] age, 4.78 [1.278] years); 10 boys (43.5%) and 13 girls (56.5%) received 300 mg dupilumab every four weeks and TCI. …”
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Malignant Granular Cell Tumor of the Back: A Case Report and Review of the Literature by Laura Stone McGuire, Danny Yakoub, Mecker G. Möller, Andrew Rosenberg, Alan Livingstone

“…Following surgery, patient was started on Pazopanib 800 mg/day based on phase III randomized trial data in the treatment of soft tissue sarcomas showing this as a potential novel therapy for malignant granular cell tumors.…”
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Impact of Psychosocial Factors on Quality of Life: A Case Study of End Stage Renal Disease by Iqra Nazar, Dr. Fatima Kamran, Dr. Rafia Rafique, Dr. Ghulam Ishaq

“…The intervention plan comprised of psychoeducation, cost and benefit analysis, coping statements, role playing technique, religious coping anger management, attention strategy technique, baseline chart and ABC model of Cognitive Behavioral Therapy (CBT). The intervention plan showed significant improvement in managing psychosocial targeted areas. …”
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Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases by Muneo Yamaguchi, Shintaro Nakao, Mitsuru Arima, Iori Wada, Yoshihiro Kaizu, Feng Hao, Shigeo Yoshida, Koh-hei Sonoda

“…Vitreoretinal diseases including diabetic retinopathy, age-related macular degeneration, and proliferative vitreoretinoapthy are still a major cause of blindness. While anti-VEGF therapy has recently been widely used for vitreoretinal disorders due to its efficacy, attention has been drawn to new unmet needs. …”
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Brain Networks Connectivity in Mild to Moderate Depression: Resting State fMRI Study with Implications to Nonpharmacological Treatment by Dmitry D. Bezmaternykh, Mikhail Ye. Melnikov, Andrey A. Savelov, Lyudmila I. Kozlova, Evgeniy D. Petrovskiy, Kira A. Natarova, Mark B. Shtark

“…Coupling of another pair, initially stronger in depression, increased in therapy though was unrelated to improvement. The results demonstrate possible role of within-DMN and DMN-ECN functional connectivity in depression treatment and suggest that neural mechanisms of nonpharmacological treatment action may be unrelated to normalization of initially disrupted connectivity.…”
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Interaction between dipeptidyl-peptidase-4 inhibitors and drugs acting on renin angiotensin aldosterone system for the risk of angioedema: a pharmacovigilance assessment using disp... by Kannan Sridharan, Gowri Sivaramakrishnan

“…Clinical outcomes were comparable between monotherapy and combination therapy groups. Conclusion This pharmacovigilance analysis reveals significant safety signals for angioedema with specific DPP-4i combinations with RAAS-interfering drugs, suggesting potential drug-drug interactions. …”
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Bilateral Transplantation of Allogenic Adult Human Bone Marrow-Derived Mesenchymal Stem Cells into the Subventricular Zone of Parkinson’s Disease: A Pilot Clinical Study by N. K. Venkataramana, Rakhi Pal, Shailesh A. V. Rao, Arun L. Naik, Majahar Jan, Rahul Nair, C. C. Sanjeev, Ravindra B. Kamble, D. P. Murthy, Krishna Chaitanya

“…All patients received BM-MSCs bilaterally into the SVZ and were followed up for 12 months. PD patients after therapy reported a mean improvement of 17.92% during “on” and 31.21% during “off” period on the UPDRS scoring system. …”
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The role of lipids and lipids lowering drugs in human papillomavirus (HPV) and HPV-associated cancers by Ehsan Shabani, Aida Hasanzadi, Omer Qutaiba B. Allela, Radhwan Abdul Kareem, Riyad E. Abed, Ali M. Ali Al-Nuaimi, Zainab H. Athab, Shiva Khodarahmi

“…In addition, lipids are critical in producing cellular energy, the epithelial-mesenchymal transition (EMT) process, and therapy resistance of HPV-related cancers (HRCs). …”
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The Crosstalk between Mesenchymal Stem Cells and Macrophages in Bone Regeneration: A Systematic Review by Rita Lih-Ying Shin, Chien-Wei Lee, Oscar Yuan-Jie Shen, Hongtao Xu, Oscar Kuang-Sheng Lee

“…The results may serve as a useful reference for definite success in MSC-based therapy based on the critical interaction with macrophages.…”
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A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Les... by Fariba Jaffary, Mohammad Ali Nilforoushzadeh, Amirhossein Siadat, Elaheh Haftbaradaran, Nazli Ansari, Elham Ahmadi

“…Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years. …”
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Tumor microenvironment–responsive and modulatory manganese-based nanoenzyme for enhanced tumor immunotherapy by Qi Yang, Qiong Wu, Haiyan Liu, Jiandong Wu, Feng Ma, Xiaofeng Tian

“…We found that this artificial nanoenzyme promoted peroxidase-like and catalase-like activities and catalyzed the in-situ decomposition of H2O2, a metabolic waste product in the TME, into ∙OH and O2, resulting in a ROS burst for killing tumors and relieving hypoxic TME to enhance cancer therapy. Besides the photothermal effect and the enhancement of ROS burst-induced immunogenic cell death, combination of Mn2+ released from Mn-based nanoenzyme in acidic TME and programmed death-ligand 1 blockade triggered a significant anti-tumor immune response. …”
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Anaerobic Bacteremias in Left Ventricular Assist Devices and Advanced Heart Failure by David R. Murillo-Garcia, Julian Galindo, Natalia Pinto, Gabriel Motoa, Esther Benamu, Carlos Franco-Paredes, Daniel B. Chastain, Andrés F. Henao-Martínez

“…There are two categories of LVADs patients: (1) bridge-to-transplant and (2) destination therapy. Advanced heart failure and destination LVADs often carry a poor prognosis. …”
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Pengaruh metode concept sentence terhadap keterampilan menulis karangan narasi sekolah dasar by Dwi Wahyuni, Riris Nurkholidah Rambe

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The Impact of Different Oxygen Delivery Methods on Corneal Epithelial Repair after Injury by Shanshan Li, Qingfen Tian, Gang Ding, Yuqin Sun, Zhongkai Hao, Xu Wang, Chenming Zhang, Yuan Tao

“…The hyperbaric oxygen therapy is often used in the management of acid and base burns of the eyes. …”
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Hospice care with Traditional Chinese medicine characteristics for a patient with small cell lung cancer with multiple systemic metastases (1例小细胞肺癌伴全身多发转移患者的中医特色安宁疗护)... by LU Meiling (卢美玲)

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Olfactory transport efficiency of the amorphous and crystalline manganese oxide nanoparticles by A. V. Romashchenko, D. V. Petrovskii, M. B.  Sharapova, Y. M. Moshkin, K. E. Kuper, K. N.  Morozova, E. V. Kiseleva, M. P. Moshkin

“…Data on the different intake of amorphous and crystalline nanoparticles from the nasal cavity to the brain, as well as the evidence for the key role of the mucosal layer in differentiating the penetrating power of these particles will be useful in developing approaches to assessing air pollution and optimizing the methods of inhalation therapy.…”
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