Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Inadequate response to steroid therapy for aGVHD is associated with poor prognosis and high mortality, including among pediatric patients, who are the focus of this study. …”
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Optimizing Extractability, Phytochemistry, Acute Toxicity, and Hemostatic Action of Corn Silk Liquid Extract by Zead Helmi Abudayeh, Uliana Karpiuk, Viktoriia Kyslychenko, Qais Abualassal, Loay Khaled Hassouneh, Sami Qadus, Ahmad Talhouni

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Risk Predictors for Mortality in Inpatients with Cancer and Coronavirus Disease 2019 during the Omicron Wave by Kuan-Yu Chen, Chih-Cheng Lai, Chien-Tai Huang, Yin-Hsun Feng

“…Univariate logistic regression revealed the following factors to be significantly associated with a higher risk of inhospital mortality among the patients with cancer and COVID-19: nosocomial COVID-19 infection (P = 0.037), lung metastasis (P = 0.005), received anticancer therapy in the preceding 3 months (P = 0.083), active and progressing cancer (P = 0.008), and quick Sequential Organ Function Assessment (qSOFA) score ≥2 (P < 0.001). …”
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Lifetime progression of IgA nephropathy: a retrospective cohort study with extended long-term follow-up by Mariell Rivedal, Ole Petter Nordbø, Yngvar Lunde Haaskjold, Rune Bjørneklett, Thomas Knoop, Øystein Eikrem

“…Methods We utilized a cohort of 400 Norwegian IgAN patients, from diagnosis to the occurrence of death, initiation of kidney replacement therapy (KRT), or the latest follow-up. Recorded proteinuria (n = 2676) and creatinine (n = 8738) measurements were retrieved. …”
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Bladder cancer. A retrospective analysis of the use of vinfluvin in real clinical practice by A. S. Zhabina, A. I. Novikov, F. V. Moiseenko, N. M. Volkov, E. O. Stepanova, E. V. Artemeva, N. H. Abduloeva, V. M. Moiseenko

“…Adverse events were observed in 28,4 %, most of them were 1-2 grades. 2 patients stopped therapy due to adverse events.Conclusion. In our analysis vinflunine was more effective than in randomized clinical trial and other studies from real practice in Europe. …”
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Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger by Aminata Iro, Moustapha Mahamane Lamine, Ramatoulaye Hamidou Lazoumar, Ibrahim Alkassoum, Daou Maman, Harouna Amadou Mahaman Laouali, Mahamadou Doutchi, Seydou Maiguizo, Ibrahim Maman Laminou

“…Pretransfusion diagnosis or posttransfusion therapy should be instituted to prevent it.…”
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A rare case of recurrent adenoid cystic carcinoma of the breast with weak hormone receptor positivity by Jonathan W. Ray, MD, Mena Louis, DO, Nathaniel Grabill, MD, Jaime Morel Ruiz, MD, Priscilla Strom, MD

“…Hormone receptor positivity raises considerations for hormonal therapy, not standard for typically triple-negative ACC. …”
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Cystitis glandularis due to Escherichia coli infection in a diabetic Miniature Schnauzer: a case report by J. P. Rey Amunategui, D. Echeverria, A. Duchene

“…After initiation of antibiotic therapy and pain management, the dog's clinical signs improved markedly until complete remission of the bladder lesions. …”
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Navigating Extrapulmonary Tuberculosis: A Case Series from a Tertiary Care Facility Highlighting Rare Presentations, Diagnostic Challenges, Drug Resistance, and Therapeutic Complex... by Megha R. Pathak, Karan Jaykrushna Pandya, Surabhi P. Ramwani, Anil Pingalsur, Shifa Karatela, Jitendra A. Sisodia, Amit R. Dedun

“…EP-TB mimics common infections which pose diagnostic dilemma, requires extensive diagnostics that culminate into therapeutic delay often resulting in irrational and empirical institution of antitubercular therapy (ATT) in challenging cases. This supplemented by poor treatment compliance resulted in emergence of Drug-resistant (DR) strains of EP-TB which further impedes the path to recovery. …”
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Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins by Yan Wang, Xin Qian, Yubo Wang, Caiyuan Yu, Li Feng, Xiaoyan Zheng, Yaya Wang, Qiuhong Gong

“…Consequently, extensive research has focused on optimizing TRAIL‐based therapies, with one of the most common approaches being the construction of TRAIL fusion proteins. …”
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Tantangan menuju pendidikan unggul: membangkitkan produktivitas institusi pendidikan untuk kualitas pendidikan yang lebih baik di Indonesia by Efi Miftah Faridli, Nurul Abidin, Sutama Sutama, Anam Sutopo, Budi Murtiyasa

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Data characterizing a panel of biodegradable cross-linked polyester implants for sustained delivery of an anti-viral drugMendeley Data by Sungmin Jung, Jack Bufton, Zeqing Bao, Wonjoon Cho, Dean Aguiar, Christine Allen

“…Tenofovir alafenamide (TAF) is currently administered orally to patients for treatment of chronic hepatitis B virus infection and as a part of a combination therapy for human immunodeficiency virus (HIV) infection. …”
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Biomarkers of Oxidative Stress and Personalized Treatment of Pulmonary Tuberculosis: Emerging Role of Gamma-Glutamyltransferase by Etienne Mokondjimobe, Benjamin Longo-Mbenza, Jean Akiana, Ulrich Oswald Ndalla, Regis Dossou-Yovo, Joseph Mboussa, Henri-Joseph Parra

“…The objectives were (i) to evaluate the impact of acute pulmonary tuberculosis (PTB) and anti-TB therapy on the relationship between AST, ALT, and GGT levels in absence of conditions related to hepatotoxicity; (ii) to evaluate the rate and the time of alterations of AST, ALT, and GGT. …”
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Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies by Gui-Chen Ye, Hao Peng, Jia-Cheng Xiang, Ling-Tao Miao, Cheng-Zhi Liu, Shao-Gang Wang, Qi-Dong Xia

“…We found that some microbiotas may be associated with prostate cancer progression and a special microbiome in metastatic prostate cancer may exist. The anti-androgen therapy can significantly change both the intratumor and gut microbiome. …”
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Prognostic significance of right subdiaphragmatic washing cytology in patients with endometrial cancer by Takanori Yokoyama, Shinichi Okame, Mika Okazawa-Sakai, Etsuko Fujimoto, Yumi Hibino, Norihiro Teramoto, Kazuhiro Takehara

“…Our results suggest that the prognostic significance of peritoneal cytology may differ depending on the collection site in endometrial cancer and provide new insights to select patients for adjuvant therapy.…”
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Right heart reverse remodeling: “facta non verba” by Tommaso Recchioni, Giovanna Manzi, Alexandra Mihai, Francesca Ileana Adamo, Annalisa Caputo, Domenico Filomena, Giorgia Serino, Silvia Papa, Nadia Cedrone, Carmine Dario Vizza, Roberto Badagliacca

“…Evidence supports initial triple therapy, including parenteral prostanoids, as the most effective approach to reduce PVR enough to facilitate RHRR and thus achieve the low-risk status.…”
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Abdominal Pain as First Manifestation of New Coronavirus Infection COVID-19 by M. R. Skhirtladze, A. A. Timofeeva, E. L. Bueverova, M. N. Aladin, R. T. Rzayev

“…Diagnosis: new coronavirus infection COVID-19, severe degree, community-acquired bilateral polysegmental pneumonia, severe degree, respiratory failure type 1. Therapy with azithromycin, hydroxychloroquine, enoxaparin subcutaneously. …”
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Tacrolimus trough level and oxidative stress in Tunisian kidney transplanted patients by Mariam Ammar, Soumaya Yaich, Ahmed Hakim, Hanen Ghozzi, Zouheir Sahnoun, Mohamed Ben Hmida, Khaled Zghal, Lobna Ben Mahmoud

“…Patients with LL-TAC had lower MDA levels and higher GSH levels and GPx activity compared with the NL-TAC and HL-TAC groups (p < 0.05).Conclusion Our results have shown that in KT patients, despite the recovery of kidney function, the TAC reduced but did not normalize oxidative stress levels in long-term therapy, and the TAC effect significantly depends on the concentration used.…”
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METTL1 coordinates cutaneous squamous cell carcinoma progression via the m7G modification of the ATF4 mRNA by Xinru Zhang, Tong Chen, Fanrong Zhang, Huanhuan Shi, Xiang Li, Zhijuan Wang, Dong Wang, Chao Hou

“…In conclusion, our results underscore the critical role of METTL1 and m7G modification in cSCC tumorigenesis, suggesting a promising target for future cSCC therapies.…”
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A Unique and Rare Presentation of Adult Congenital Heart Disease: Common Atrium Associated with Coronary Aneurysms and Fistula by Muhammad Shabbir Rawala, Alex Munoz, Mohammad Hassan Pervaiz

“…It is unclear at this point if surgical treatment to correct the anatomical defect (which would be probably palliative) would be superior to conservative medical therapy. Besides, the presence of coronary arteriovenous fistula would make the decision-making process more complex regarding surgical versus conservative management.…”
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