Understanding integrative approach of translational bioinformatics on cardiovascular disease: Myocardial Ischemia by Yeswanth Ranganathan, Saayaa Nazar, Ravi Shankar Krishnan, Yuvaraj Dinakarkumar, Vijayalakshmi Varadarajan, Lenita Sebastian, Brindha Rethinam

“…Translational bioinformatics bridges the gap between biological discoveries and clinical applications, enabling early disease identification, therapy response confirmation, and prognosis prediction. …”
Get full text

Rare Presentation of Cardiotoxicity Related to 5-Fluorouracil by Mariam Charkviani, Natia Murvelashvili, Francisco Barrera, Alisha Sharma, Randa Sharag Eldin, Nur Un Nisa Nabil

“…Recognition of 5-FU cardiotoxicity is clinically important as after the rapid sensation of therapy, cardiotoxicity can be completely reversible, and on the other hand, readministration may lead to serious damage of the heart and even death. …”
Get full text

Innate immune cells in vascular lesions: mechanism and significance of diversified immune regulation by Jinjing Wu, Yulu Qian, Kuang Yang, Shuhua Zhang, Erming Zeng, Daya Luo

“…The combination treatment of antiangiogenic therapy and immunotherapy breaks the traditional treatment pattern. …”
Get full text

Rheumatoid Arthritis Effects on Kidney and Liver and their Correlations with CDAI by Tamara Salman Mohammed, Raya Ezat Maroof, Ali Hussein Al-Hafidh

“…The study showed that the levels of urea, creatinine, GPT, and GOT were either normal or slightly elevated and they are non-significantly associated with RA disease activity, the little effect of RA on kidney and liver may be related to the low doses of methotrexate and corticosteroid therapy which used mostly for these patients and didn’t reach to toxicity. …”
Get full text

Proceedings of clinical trials on bile tract cancer by XIONG Yichen, YANG Ziyi, SANG Yuer, GONG Wei

“…In terms of targeted therapy, breakthroughs have been made in the development of HER2-targeting drugs such as zanidatamab, T-DXd, and neratinib. …”
Get full text

Manajemen pendidikan anak usia dini: peluang dan tantangan masa depan by Alfin Julianto, Nina Kurniah, Muhammad Kristiawan, Eko Risdianto, Nelda Sari Siregar

Get full text

Pengaruh self presentation, opinion leadership, customer engagement, dan self expression terhadap perilaku e-wom (studi kasus di bukit gado-gado kota Padang) by Nadhila Sari, Meizi Syafri Yendi, Kristiana Astuti, Kendis Anwar, Hani Maisyarah Batubara, Susi Evanita

Get full text

New treatment options for generalized myasthenia gravis by Antanas Vaitkus, J. Čiauškaitė, M. Malakauskaitė, M. Baublytė

“…In this article, we review publications that analyze biological therapy and its novelty in the treatment of myasthenia gravis. …”
Get full text

Treatment of Priapism Secondary to Drugs for Erectile Dysfunction by José Pablo Saffon Cuartas, Carolina Sandoval-Salinas, Juan M. Martínez, Héctor A. Corredor

“…The results suggest that in men treated for priapism secondary to the use of sexual impotence drugs, initial treatment with local measures and etilefrine can achieve detumescence, decreasing the need for invasive procedures or surgery as a first-line therapy alternative. It is necessary to carry out research studies to confirm this hypothesis.…”
Get full text

Investigating the Existence of Ribosomal Protein L5 Gene in Syrian Strain of Leishmania tropica Genome: Sequencing It and Evaluating Its Immune Response as DNA Vaccine by Mohammad Maarouf, Alyaa A. Abdlwahab

“…Until now, there are no effective protective strategies, safe therapy, or efficacious vaccine to protect from this infection. …”
Get full text

Severe Wound Infection with Photobacterium damselae ssp. damselae and Vibrio harveyi, following a Laceration Injury in Marine Environment: A Case Report and Review of the Literatur... by Jörg Hundenborn, Steffi Thurig, Mechthild Kommerell, Heike Haag, Oliver Nolte

“…Management with daily wound dressing and antibiotic therapy (ofloxacin empirically, followed by doxycycline after availability of microbiology) led in the reported case to a favorable outcome, which seems to be, however, the exception based on a review of the available literature.…”
Get full text

Embolic risk management in infective endocarditis: predicting the ‘embolic roulette’ by Adela Mihaela Șerban, Diana Pepine, Andreea Inceu, Alexandra Dadarlat, Alexandru Achim

“…Therefore, future perspectives should focus on identifying high-risk profiles for EE and investigating whether early surgical intervention benefits these patients, even if they respond favourably to antibiotic therapy. This review explores current literature on echocardiographic and biomarker predictors of EE in IE, aiming to enhance clinical strategies for mitigating embolic complications and improving patient outcomes.…”
Get full text

High-Cadence Cycling Promotes Sustained Improvement in Bradykinesia, Rigidity, and Mobility in Individuals with Mild-Moderate Parkinson’s Disease by Angela L. Ridgel, Dana L. Ault

“…Exercise has been shown to be an important adjunct therapy to medication in Parkinson’s disease (PD). …”
Get full text

Pengaruh konseling kelompok dengan media kartu terhadap pencegahan perilaku agresi di sekolah by Yusida Imran, Nur Kur'ani

Get full text

Intravascular Leiomyomatosis as a Rare Cause of Nonthrombotic Pulmonary Embolism by Julie Van Maercke, Anne-Sophie Van Rompuy, Willy Poppe, Tom Verbelen, Marion Delcroix, Catharina Belge

“…As she was not responding to adequate anticoagulant therapy, intima sarcoma of the pulmonary artery was suspected, and a pulmonary endarterectomy (PEA) was performed. …”
Get full text

Construction of oncolytic reporter influenza viral vectors and assessment of their safety following intracranial administration in rats by A. A. Pulkina, A. S. Mustafaeva, E. A. Romanovskaya-Romanko, M. A. Plotnikova, O. O. Ozhereleva, M. A. Shuklina, L. N. Kiseleva, Y. S. Alekseeva, N. S. Kurmazov, A. R. Muslimov, A.-P.S. Shurygina, M. A. Stukova

“…INTRODUCTION: Oncolytic viruses are a promising approach for treating malignant brain tumors as part a of combination therapy. OBJECTIVE: To develop reporter influenza A viruses expressing NanoLuc luciferase and evaluate their safety following intracranial administration in rats. …”
Get full text

Radiological Imaging and Analysis of Laboratory Values in Case of Acute Ischemic Stroke by Necmi Baykan, Mustafa Alpaslan

“…Pathologically the majority of patients had hyperglycemia, vitamin D deficiency and low HDL cholesterol levels. Thrombolytic therapy was applied in six patients and three patients benefited and one patient died due to bleeding. 13.6% of the patients were treated in the intensive care unit. …”
Get full text

High-fidelity immersive virtual reality environments for gait rehabilitation exergames by Laura Schalbetter, Adrienne Grêt-Regamey, Fabian Gutscher, Ulrike Wissen Hayek

“…This research presents the development of a head-mounted display VR (HMD-VR) exergame for gait therapy. The novelty lies in the use of high-fidelity immersive environments implementing 3D geospatial data and motion to create targeted therapeutic applications that closely mimic reality while harnessing the environment’s restorative functions.MethodsWe integrated 3D point clouds from laser scans and geolocated ambisonic sound recordings into a game engine. …”
Get full text

Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Because there have been no therapeutic strategies developed to target inflammation and oxidative stress, there is a continuing need for new and improved therapy. As a result, there has been increasing interest in complementary and alternative medicine with anticancer potential. …”
Get full text

Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients by Yuanyuan Zhang, Chunyang Tian, Xuejian Liu, He Zhang

“…Meanwhile, CALCA, CDK6, NRXN1, SMAD4, SOCS3, and NCAM1 were further identified to be potential diagnosis and therapy targets for MI.…”
Get full text