Standard flushing and sealing of venous indwelling catheter and related nursing management in a case of gangrene (1例脱疽患者静脉留置导管冲封管操作规范及护理) by ZHENG Jiaqi (郑佳琪), ZHI Hui (智慧)

“…According to the Infusion Therapy Standards of Practice, the catheter flushing and sealing operation was performed, and blood return and catheter blockage after catheter sealing were observed. …”
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LncRNA HOXA10-AS as a novel biomarker and therapeutic target in human cancers by Xin Hu, Yong Wang, Sijia Zhang, Xiaosi Gu, Xiaoyu Zhang, Lianlian Li, Lianlian Li

“…In conclusion, HOXA10-AS is expected to serve as an ideal clinical biomarker and an effective cancer therapy target.…”
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Evaluation of Provider Screening Practices for Fracture Risk Assessment among Patients with HIV Disease by Faryal Mirza, Sabina Zawadzka, Anne Abbate, Michael Thompson, Dorothy Wakefield, Lisa M. Chirch

“…Increased duration of antiretroviral therapy use was associated with a lower likelihood of fragility fracture.…”
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Mismatch prime editing gRNA increased efficiency and reduced indels by Jidong Fei, Dongdong Zhao, Caiyi Pang, Ju Li, Siwei Li, Wentao Qiao, Juan Tan, Changhao Bi, Xueli Zhang

“…Combining mpegRNA with epegRNA further increases efficiency up to 14-fold, or 2.4-fold in PE4max/PE5max systems, underscoring its potential in research and therapy. AlphaFold 3 analysis suggests that the optimal mpegRNA structure contributes significantly to improved editing outcomes. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…MAGEA4-based TCR-T cell therapy and cancer vaccines show clinical potential. …”
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Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] by Jelena Ostojic, Safija Herenda, Semira Galijasevic, Borivoj Galic, Mladen Milos

“…Recently research shows that horseradish peroxidase, HRP, when combined with other compounds, is highly reactive toward different human tumour cells and that better understanding of catalytic mechanism and inhibition HPR could lead to a new targeted cancer therapy. Thus, the inhibition of HRP activity by dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] was investigated for possible explanation of previously observed antitumour activities of this promising drug. …”
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Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A by Tohru Takahashi, Yumiko Maruyama, Mayuko Saitoh, Hideto Itoh, Mitsuru Yoshimoto, Masayuki Tsujisaki

“…Epstein-Barr virus (EBV) associated lymphoproliferative disorder (LPD) after immunosuppressive therapy for aplastic anemia (AA) is extremely rare in a nontransplant setting and has not been well described. …”
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Combination of functional dyspepsia syndrome and irritable bowel syndrome by V. T. Ivashkin, Ye. A. Poluektova

“…It was possible to achieve significant improvement in the state of health on the background of therapy. However, the overall prognosis for this patient is unfavorable. …”
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Incidence and Predictors of Structural Valve Deterioration after Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis by Yu-Xiang Long, Zeng-Zhang Liu

“…Transcatheter aortic valve replacement (TAVR), widely used as an alternative therapy in patients with severe aortic stenosis, is expected to be offered to low-risk patents with a longer life expectancy. …”
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Fenofibrate Exerts Antitumor Effects in Colon Cancer via Regulation of DNMT1 and CDKN2A by Rui Kong, Nan Wang, Wei Han, Wen Bao, Jie Lu

“…The PPARA agonist, fenofibrate, might serve as an applicable agent for epigenetic therapy of colon cancer patients.…”
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Drug Abuse Prevention Among Students In Improving The Lives Meaning Through Counseling Logo by Kadek Suranata

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Kajian pendidikan karakter dimasa pandemi covid-19 studi kasus pada sekolah berasrama by Marlina Marlina, Zulfi Hendri

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Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article by Syed Faizan Mehdi, Muhammad Hamza Qureshi, Salman Pervaiz, Karishma Kumari, Edwin Saji, Mahnoor Shah, Ahmad Abdullah, Kamran Zahoor, Hafiza Amna Qadeer, Disha Kumari Katari, Christine Metz, Lopa Mishra, Derek LeRoith, Kevin Tracey, Michael J. Brownstein, Jesse Roth

“…Further research is essential to look into the hormonal changes that occur during sepsis, not only to understand their potential relevance in therapy but also because they may serve as prognostic indicators.…”
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Angiojet System Used in the Treatment of Submassive Pulmonary Embolism: A Case Report of Two Patients by Jinbo Liu, Tianrun Li, Wei Huang, Na Zhao, Hongwei Zhao, Hongyu Wang

“…Here, we reported two submassive PE cases who were treated with the Angiojet system successfully, to provide some advice for the therapy of submassive PE. Method. Two patients with suffocation were admitted to our hospital. …”
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A Clinical Study on Initial Experience of COVID-19 ARDS in Obstetric Patients at a Tertiary Care Centre in India by Sheeba Marwah, Reenu Kanwar, Shahida Naghma, Anjali Dabral, Nitesh Gupta

“…The clinical presentation as well as response to therapy is highly variable, and since no conclusive proven treatment is available yet, prevention and symptomatic treatment remains the mainstay of management. …”
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Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…These findings suggest the potential of DL+TMZ combination therapy as an effective treatment for GBM.…”
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International Burden of Chronic Kidney Disease and Secondary Hyperparathyroidism: A Systematic Review of the Literature and Available Data by Elizabeth Hedgeman, Loren Lipworth, Kimberly Lowe, Rajiv Saran, Thy Do, Jon Fryzek

“…Estimates of the population prevalence of maintenance dialysis therapy ranged from 79 per million population (pmp; China) to 2385 pmp (Japan); incidence rates ranged from 91 pmp (United Kingdom) to 349 pmp (United States). …”
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Fertility Preservation in Girls by Jennia Michaeli, Michael Weintraub, Eitan Gross, Yehuda Ginosar, Vardit Ravitsky, Einat Eizenman, Eduardo Mitrani, Meital Lebovich, Neri Laufer, Stephen Kennedy, Ariel Revel

“…Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal function after resumption of therapy. Effective counseling and management of pediatric patients is crucial for preserving their future reproductive potential. …”
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Case of acute drug-induced hepatitis after halothane anesthesia by I. Yu. Pirogova, Ye. V. Berestova, O. Yu. Bastrikov, Ye. B. Kovaleva, T. P. Petukhova, M. V. Guseva, I. A. Gubina, I. V. Rezepin, S. P. Sinitsyn

“…The most important factors determining favorable prognosis at drug-induced liver disease, include adequate doses of glucocorticosteroids, application of MARS-therapy and absence of background liver disease. Application of differential diagnostics algorithms and prognostic scales at drug-induced liver disease helps clinician to choose proper treatment approach at specific stage.…”
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Evaluation of efficacy of photodynamic disinfection against enterococcus faecalis and compare it with the effect of different endodontic irrigant activation techniques. by Amanda George Haskiyal, Dara Hamarashid Saeed

“…Conclusion: As an additional method, photodynamic therapy may increase the disinfection capacity of traditional endodontic treatment against E. faecalis in the root canal. …”
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