Antibacterial potential of celery (Apium graveolens L.) extract gel against Staphylococcus aureus by Martinus Ezra Sunarno, Anita Lidesna Shinta Amat, Arley Sadra Telussa, Prisca Deviani Pakan

“…Conventional topical therapies often lead to side effects such as contact dermatitis and pruritus, compounded by the increasing problem of antibiotic resistance. …”
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Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain by Han-Chung Lee, Kai-Leng Tan, Pike-See Cheah, King-Hwa Ling

“…Since both human and mouse models of DS brain exhibit less neurons and a higher percentage of cells with astrocytic phenotypes, understanding the role of JAK-STAT signaling in DS brain development will provide novel insight into its role in the pathogenesis of DS brain and may serve as a potential target for the development of effective therapy to improve DS cognition.…”
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Comparative Study of Periodontal Health in Patients with Fixed Braces Versus Clear Aligners by Selvakumar Annamalaisamy, B.S. Malthesh, G. M. Shashikumar, Sreedhara Shantharam, P Kiran Kumar

“…Background: Orthodontic therapy is often used to cure dental malocclusions; however, since orthodontic equipment is difficult to keep clean, it might have an adverse effect on periodontal health. …”
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Magnetic precision: Unleashing the therapeutic potential of paclitaxel-loaded nanoparticles in breast cancer treatment by N. Shobhana, N Raghavendra Naveen, Prakash Goudanavar

“…The integration of targeted nanocarrier systems into breast cancer therapy represents a promising avenue for advancing precision medicine and improving patient outcomes.…”
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Multidisciplinary Vulvar Cancer Management: The Dermatologist’s Perspective by Marta Cebolla-Verdugo, Victor Alfredo Cassini-Gómez de Cádiz, Juan Pablo Velasco-Amador, María Zulaika-Lloret, Francisco Manuel Almazán-Fernández, Ricardo Ruiz-Villaverde

“…The article also discusses recent advances in treatment guidelines and targeted therapies, underscoring the importance of integrated care for optimizing patient outcomes in vulvar cancer.…”
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HIV Late Presenters in Asia: Management and Public Health Challenges by Chen Seong Wong, Lyu Wei, Yeon-Sook Kim

“…They also have a higher mortality rate and generally exhibit poorer immune recovery following combined antiretroviral therapy (cART). As such, late HIV presentation leads to increased resource burden and costs to healthcare systems. …”
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Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners by Katarzyna Popiolek-Barczyk, Anna Piotrowska, Wioletta Makuch, Joanna Mika

“…Biphalin may be a putative drug for future pain therapy, especially for the treatment of neuropathic pain, when the lower analgesic effects of morphine are correlated with profound microglial cell activation.…”
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SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques. by Omotayo Farinre, Tzoalli Anaya, Alexis C King, Kedan Endrias, Anne H Hébert, Alison L Hill, Sherrie Jean, Jennifer S Wood, Stephanie Ehnert, Shan Liang, Gregory M Laird, Rosemarie D Mason, Mario Roederer, Jeffrey T Safrit, Maud Mavigner, Ann Chahroudi

“…The latent viral reservoir remains the major barrier to HIV cure, placing the burden of strict adherence to antiretroviral therapy (ART) on people living with HIV to prevent recrudescence of viremia. …”
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Deep-insights: Nanoengineered gel-based localized drug delivery for arthritis management by Anitha Sriram, Harshada Ithape, Pankaj Kumar Singh

“…Gel-based nanoengineered therapy employs a gel matrix to incorporate the drug-encapsulated nanocarriers. …”
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Absence of mTOR Inhibitor Effect on Hepatic Cyst Growth: A Case Report of a Kidney Transplant Recipient with Autosomal Dominant Polycystic Kidney Disease by L. Friedrich, F. Barbey, M. Pascual, J.-P. Venetz

“…The interest of our case resides in the followup by MRI imaging during the mTOR inhibitor treatment and 15 months after the restart of the initial immunosuppressive therapy. This observation indicates that mTOR inhibitors did not have significant effect on cyst-associated hepatic growth in our patient, which is consistent with some results of recent large clinical studies.…”
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Potensi Eugenol Fraksi Etil Asetat Bunga Cengkeh terhadap Proliferasi Kanker Serviks (HeLa Cell Line) by Fajri Rahendra Pratama, Annisa Permata Sari, Aprilia Susanti, Hasya Syakira, Amilia Salsabila, Dessy Arisanty

“…<strong>Conclusion:</strong> Based on its potential, clove flower can be a candidate for cervical cancer cell therapy (HeLa Cell Line) in the future.</p><p><strong>Keywords</strong>:  anti-cervical cancer, cervical cancer, cell proliferation, MTT assay, scratch assay </p>…”
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A CLINICAL CASE OF HOSPITAL-ACQUIRED PNEUMONIA CAUSED BY KLEBSIELLA PNEUMONIA, DUE TO CONTACT WITH A FAMILY MEMBER by N.D. Gerasymenko, N.I. Digtiar

“…Identification of nosocomial and community-acquired pneumonia involves a particular flora of pathogens and, accordingly, involves empiric therapy. Routine analysis of sputum according to Gram gives approximate data, which is a clarification for empiric treatment. …”
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The Influence Of Learning Media, Facilities, and Learning Interest on Students Motivation and Economic Learning Outcome At SMA Negeri District Tenayan Raya by Mira Maharani, Gusnardi Gusnardi, Gimin Gimin

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Clinical Characteristics and Outcomes of Interstitial Lung Disease Patients with Acute Respiratory Failure Admitted to the ICU by Sourabh Pahuja, Milta Kuriakose, Satyam Agarwal, Pradeep Bajad, Arjun Khanna, Deepak Talwar

“…It is essential to perform all the diagnostic examinations at the earliest to ensure prompt initiation of the most appropriate therapy and lower hospital mortality. Distinguishing those patients who have a known cause for their ILD from those who do not was found to be crucial for deciding the most appropriate management.…”
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Polatuzumab vedotin combined with bendamustine and rituximab for relapsed/refractory diffuse large B-cell lymphoma: A systematic review protocol. by Mohammadreza Eslami, Mahdi Mehrabi, Mehrdad Payandeh, Fakhredin Saba

“…Polatuzumab vedotin in combination with bendamustine and rituximab (Pola-BR) has demonstrated promising efficacy and safety as salvage therapy for R/R DLBCL. This systematic review protocol aims to comprehensively evaluate the efficacy of Pola-BR for the treatment of R/R DLBCL by synthesizing data from relevant randomized controlled trials.…”
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Perlindungan penggunaan aplikasi makanan dan minuman online dalam information legality jaminan kehalalan produk berdasarkan UU no. 11 tahun 2020 perspektif fiqih siyasah by Padia Putri, Syafruddin Syam

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Bulky Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Treated with Yttrium-90 Ibritumomab Tiuxetan by Shinobu Tamura, Tokuji Ikeda, Toshio Kurihara, Yoshiteru Kakuno, Hideki Nasu, Yoshio Nakano, Koichi Oshima, Tokuzo Fujimoto

“…Her pulmonary images and respiratory symptoms did not improve two months after receiving 4 cycles of rituximab weekly; therefore, yttrium-90 ibritumomab tiuxetan was chosen as salvage therapy. The abnormal shadow on her pulmonary images was significantly reduced two months later, and she had no symptoms without nonhematological toxicities. …”
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Sézary Syndrome with CD4/CD8 Double-Negative Neoplastic T Cells in Peripheral Blood by Yuki Kageyama, Kenshiro Tsuda, Yuma Nato, Keiki Nagaharu, Kazutaka Suzuki, Akihiko Sawaki, Hiroyuki Miyashita

“…The patient responded well to treatment with bexarotene and narrow-band ultraviolet B therapy. Analysis by multicolor flow cytometry is essential to diagnose this rare type of Sézary syndrome and evaluate the tumor burden.…”
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Bisphosphonate-Related Osteonecrosis of the Jaw: A Review of the Literature by Eder Alberto Sigua-Rodriguez, Renato da Costa Ribeiro, Ana Caroline Ramos de Brito, Natalia Alvarez-Pinzon, José Ricardo de Albergaria-Barbosa

“…The American Society for Bone and Mineral Research defines BRONJ as “an area of exposed bone in the maxillofacial region that has not healed within 8 weeks after identification by a healthcare provider in a patient who is receiving or has been exposed to a bisphosphonate and has not had radiation therapy to the craniofacial region.” Bisphosphonate-related osteonecrosis of the jaw (BRONJ) can adversely affect quality of life, as it may produce significant morbidity. …”
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Analisis risiko operasional di PT asuransi umum x by ML Denny Tewu, Timothy Victory T

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