CRT-D Therapy in Patients with Decompensated NYHA Class-Four CHF by Faisal Zaeem, Dalia Giedriemiene, Craig Coleman, Eric Crespo, Joseph Radojevic, Steven Zweibel, Jeffrey Kluger, Christopher A. Clyne

“…ACC-HRS Guidelines for Cardiac Resynchronization Therapy ICD implantation (CRT-D) do not include patients with advanced nonambulatory NYHA class-four CHF due to an expectation of limited survival. …”
Get full text

Targeting EBV Episome for Anti-Cancer Therapy: Emerging Strategies and Challenges by Febri Gunawan Sugiokto, Renfeng Li

Subjects: Get full text

Quantitative Evaluation of the Effectiveness of Erbium Glass Laser Therapy for Acne Scars by Wiktoria Odrzywołek, Anna Deda, Dagmara Kuca, Małgorzata Bożek, Krzysztof Makarski, Sławomir Wilczyński

“…Results: The use of this therapy led to significant improvements across multiple parameters. …”
Get full text

The Potential Use of the CRISPR-Cas System for HIV-1 Gene Therapy by Gabriela De Nardi Sanches-da-Silva, Luiza Fonseca Sales Medeiros, Fabio Mitsuo Lima

“…The objective of this minireview is to synthesize the current knowledge on the application of CRISPR-Cas-based gene therapy for HIV-1. The strategies encompass all steps of the viral infection cycle, from inhibition of cell invasion, through viral replication and integration inhibition, to excision of the latent provirus. …”
Get full text

Development of Anti-VEGF Therapies for Intraocular Use: A Guide for Clinicians by Pearse A. Keane, Srinivas R. Sadda

“…In this review, we provide a guide for clinicians on the development of anti-VEGF therapies for intraocular use.…”
Get full text

Targeting lipid metabolism of macrophages: A new strategy for tumor therapy by Nan Shao, Hui Qiu, Jing Liu, Daimin Xiao, Juanjuan Zhao, Chao Chen, Jiajia Wan, Mengmeng Guo, Guiyou Liang, Xu Zhao, Lin Xu

“…Tumor-associated macrophage (TAM) has emerged as a crucial regulator in tumorigenesis and promising target for tumor treatment.Aim of review: A thorough understanding of TAM lipid metabolism and its value in tumorigenesis may provide new ideas for TAM-based anti-tumor therapy.Key scientific concepts of review: TAMs can be divided into two main types, M1-like TAMs and M2-like TAMs, which play anti-tumor and pro-tumor functions in tumor occurrence and development, respectively. …”
Get full text

Digital tool as speech and language therapy for patients with post-stroke aphasia by Gerardo Ruiz Ares, Marta Martin Alonso, Ricardo Rigual, Carlos Hervás Testal, Gabriel Torres Iglesias, Laura Casado Fernandez, Elena de Celis Ruiz, Jorge Rodríguez Pardo, Jenny Carvajal Muñoz, Laura González Martín, María Alonso de Leciñana, Blanca Fuentes

Get full text

Systemic Corticosteroids Therapy in the Management of Acute Zonal Occult Outer Retinopathy by San-Ni Chen, Chang-Hao Yang, Chung-May Yang

“…Retrospective study of 9 consecutive patients of AZOOR, who received systemic steroid therapy in Changhua Christian Hospital from 2005 to 2013, is presented. …”
Get full text

Stereotactic body radiation therapy as initial treatment for head and neck cancer by Sivakamavalli Jeyachandran

“…Stereotactic Body Radiation Therapy (SBRT) emerges as a pioneering approach for primary treatment in head and neck squamous cell cancer (HNSCC) management. …”
Get full text

Reorganization of Anatomical Connectome following Electroconvulsive Therapy in Major Depressive Disorder by Jinkun Zeng, Qinghua Luo, Lian Du, Wei Liao, Yongmei Li, Haixia Liu, Dan Liu, Yixiao Fu, Haitang Qiu, Xirong Li, Tian Qiu, Huaqing Meng

“…Objective. Electroconvulsive therapy (ECT) is considered one of the most effective and fast-acting treatment options for depressive episodes. …”
Get full text

A Survey of Insulin-Dependent Diabetes—Part I: Therapies and Devices by Daisuke Takahashi, Yang Xiao, Fei Hu, Michael Lewis

Get full text

Rational emotive behavior therapy to overcome anxiety post-flood disaster by Ririanti Rachmayanie J., Akhmad Sugianto, Selamad Riyadi

Get full text

Is renal biopsy always necessary to start immunosuppressive therapy in lupus nephritis? by Vasudevan Chelliah, V Balaraman, S Ilango, S Ramesh, V Kannan Bhaba, D Shivakumar

“…Thus it might be argued that immunosuppressive therapy (steroids and mycophenolate mofetil) may be started without renal biopsy in a known SLE patient with laboratory evidence of LN and positive serology; however, robust studies are required.…”
Get full text

Preparation and Characterization of Biocompatible Polymer Particles as Potential Nanocarriers for Inhalation Therapy by Katarzyna Jabłczyńska, Magdalena Janczewska, Aleksandra Kulikowska, Tomasz R. Sosnowski

Get full text

HIV-Associated Hodgkin's Lymphoma: Prognosis and Therapy in the Era of cART by Caron A. Jacobson, Jeremy S. Abramson

“…Despite these significant advances, HIV-HL patients remain at increased risk for treatment-related toxicities and drug-drug interactions which require careful attention and supportive care to insure the safe administration of therapy. This paper will address the modern diagnosis, risk stratification, and therapy of HIV-associated HL.…”
Get full text

Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

Subjects: Get full text

Amebic Encephalitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy by Ensi Voshtina, Huiya Huang, Renju Raj, Ehab Atallah

“…Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in Western countries. A common first-line therapy offered to qualifying patients includes ibrutinib, an oral covalent inhibitor of Bruton’s tyrosine kinase. …”
Get full text

Prognostic Factors Predicting Remission Following Rituximab Therapy for Pemphigus Vulgaris by Tal Raviv, Keren Pevzner, Aviv Barzilai, Felix Pavlotsky, Sharon Baum

“…Patients with a disease duration ≤ 16 months before rituximab therapy exhibited a shorter median time to relapse. …”
Get full text

Adjunctive Therapies to Cerclage for the Prevention of Preterm Birth: A Systematic Review by Emily A. DeFranco, Amy Miyoshi Valent, Tondra Newman, Jodi Regan, Jessica Smith, Louis J. Muglia

“…The aim of this paper is to provide a thorough summary of published studies that have assessed the efficacy of adjunctive therapies used in addition to cervical cerclage as a preventive measure for preterm birth. …”
Get full text

Trends in Inflammatory Bowel Disease Therapy: A Meta-Analytic Approach by Gregory W Whiting, Joseph Lau, Bruce Kupelnick, Thomas C Chalmers

Get full text