Prognosis of unfavorable course of ulcerative colitis as indication for anticytokine therapy by A. Yu. Baranovsky, E. A. Kondrashina, A. G. Kharitonov

Subjects: Get full text

Characterization of home oxygen therapy prescription. Cienfuegos Municipality, 2022 by Aracelia Esther Valdés Zamora, Idaimy Molina del Sol, Anay de la C. Núñez Herrera, Noel A. Pardillo Mustelier, Anisbelys Álvarez

“…<p><strong>Foundation</strong>: oxygen therapy, indicated with the intention of treating or preventing hypoxia manifestations, has shown to increase survival in patients with chronic obstructive pulmonary disease and respiratory failure. …”
Get full text

TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy by Susan Waserman, Jerry Dolovich, Mary Conway, Jean S Marshall

“…However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.…”
Get full text

The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy by Qinglong Ma, Wenyang Zhang, Kongming Wu, Lei Shi

Get full text

Outcomes of Neonatal Candidiasis: The Impact of Delayed Initiation of Antifungal Therapy by Heather Cahan, Jaime G. Deville

“…Delayed institution of antifungal therapy was associated with increased mortality. In addition, length of hospitalization, duration of prior antibacterial therapy, mechanical ventilation, and CVC use, as well as evidence of end-organ disease, were associated with an adverse outcome. …”
Get full text

Difficult-to-Treat or Resistant Hypertension: Etiology, Pathophysiology, and Innovative Therapies by Vasilios Papademetriou, Costas Tsioufis, Alan Gradman, Henry Punzi

“…This special issue of the journal expoars a whole spectrum of topics related to resistant hypertension: several articles address pathophysiolog and secondary causes of resistant hypertension and modern approaches to therapy. Of interest is the referance to the newer interventional approaches, that is, Baroreceptor stimulation therapy and catheter based sympathetic renal denervation.…”
Get full text

Multifunctional biosynthesized magnetosome for multimodal imaging and combined therapy of tumor by Xiaoqing Han, Xingbo Wang, Jiao Yan, Panpan Song, Yanjing Wang, Yaqing Kang, Abdur Rauf, Haiyuan Zhang

“…Herein, biosynthesized magnetosome (Mag) from bacteria was loaded with photothermal/photodynamic agent/near infrared (NIR) fluorescence dye (IR780) and further modified with lipid-PEG-c(RGDyK) through biomembrane, forming IMagRGD for fluorescence imaging, magnetic resonance imaging, immunotherapy and photodynamic/photothermal therapy. After intravenous injection into B16F10 tumor-bearing mice, IMagRGD could efficiently accumulate in tumor tissues based on near infrared (NIR) fluorescence and magnetic resonance dual-modality imaging, and repolarize tumor-associated macrophages (TAMs) from M2 phenotype to M1 phenotype, significantly improving the effect of tumor immunotherapy. …”
Get full text

Ziwuliuzhu Acupuncture on Primary Insomnia Therapy: A Meta-Analysis by Dunbing HUANG, Shinong GU, Fanping ZHOU, Sai'e HUANG

“…Objective:To systematically review the clinical efficacy of Ziwuliuzhu acupuncture on primary insomnia therapy.Methods:Randomized controlled trials (RCT) about Ziwuliuzhu acupuncture on treating primary insomnia were electronically searched in CNKI, VIP, Wanfang Data, CBM, PubMed and the Cochrane Library. …”
Get full text

Biomimetic bioreactor for potentiated uricase replacement therapy in hyperuricemia and gout by Bin Yang, Bin Yang, Guihu Luo, Tailei Nie, Zhenglan Ban, Quanxin Ning, Jialin Zhang, Xiangru Liu, Yanhua Lin, Xiaochun Xie, Qianyun Chen, Han Zhong, Ying Huang, Pan Liao, Yan Liu, Chenyang Guo, Chuanxu Cheng, Erwei Sun, Erwei Sun

“…IntroductionUricase replacement therapy is a promising approach for managing hyperuricemia and gout but is hindered by challenges such as short blood circulation time, reduced catalytic activity, and excessive hydrogen peroxide (H2O2) production. …”
Get full text

Role of Interleukin- (IL-) 17 in the Pathogenesis and Targeted Therapies in Spondyloarthropathies by I-Tsu Chyuan, Ji-Yih Chen

“…Recently, several clinical trials targeting IL-17 pathways demonstrated the positive response of IL-17 blockade in treating AS, indicating a great potential of IL-17-targeting therapy in SpA. In this review article, we have discussed the contributing role of IL-17 and different IL-17-producing cells in the pathogenesis of SpA and provided an outline of therapeutic application of the IL-17 blockade in the treatment of SpA. …”
Get full text

Sclerostin Antibody Therapy for the Treatment of Osteoporosis: Clinical Prospects and Challenges by Claire MacNabb, D. Patton, J. S. Hayes

“…In anticipation of phase III trial results which may potentially signify a significant step in achieving market approval here, we review the preclinical and clinical emergence of sclerostin antibody therapies for both osteoporosis and alternative applications. …”
Get full text

Binocular Diplopia: A Possible Adverse Effect of Fluoroquinolone Therapy by Mariama Touray, Victoria Ando, Erwin Samutelela, Jean-Philippe Zuber

Get full text

Modern approach to infusion therapy of pregnant women with gestational hypertension by O.V. Vaskiv, A.P. Grigorenko, O.G. Gorbatyuk, A.S. Shatkovska, A.M. Binkovska, I.A. Priymak

“…The second group included 20 patients with gestational hypertension on basic therapy with methuldopa only. The control group included 23 women with physiological pregnancy. …”
Get full text

Adjuntive nicergoline therapy for severe persistent corneal epithelial defects. by Valeria Oliva-Biénzobas, Enrique O. Graue-Hernandez, Guillermo Raul Vera-Duarte, Jesus Cabral-Macías, Juan Serna-Ojeda, Victor Boullosa, Arturo Ramirez-Miranda, Vishal Jhanji, Victor L. Perez, Alejandro Navas

“…Results: Two male and seven female patients with persistent corneal epithelial defects unresponsive to conventional therapy treated with oral nicergoline were included. …”
Get full text

Pulse Dye Laser Therapy Successful for Elastosis Perforans Serpiginosa by Giulia Rinaldi, Alisha Chacko, Samira Batul Syed

“…Our results show that pulse dye laser therapy is a safe and effective treatment for elastosis perforans serpiginosa.…”
Get full text

RANKL-Targeted Therapies: The Next Frontier in the Treatment of Male Osteoporosis by Alicia K. Morgans, Matthew R. Smith

“…Men treated with androgen deprivation therapy experience a decline in bone mineral density and have an increased rate of fracture. …”
Get full text

Ionized Plasma Jet Therapy in Removal of Dermatosis Papulosa Nigra by Ajay Dodeja, Manjiri Oke, Milind Borkar, Shreyaa Mandawgade, Mallika Thobde

Subjects: Get full text

Clinical Effect and Aesthetic Evaluation of Minimally Invasive Implant Therapy by Kefei Li, Fang Liu, Pan Liu, Cuifang Wei, Xue Li

Get full text

Efek Pemakaian Hormone Replacement Therapy (HRT): Systematic Review by Biomechy Oktomalio Putri, Noverial Noverial

“…One effort to reduce this risk is to use Hormone Replacement Therapy (HRT). Objective: To analyzed  the effect of HRT use on postmenopausal women.Methods: This research was a systematic review by searching articles in the PubMed electronic journal with keywords used [“Premenopausal women” OR “Postmenopausal women”, OR “Menopause”] AND  [“Hormone Replacement Therapy” OR “Menopausal Hormone Therapy”] AND [“Increased risk disease” OR “Decreased risk disease”]. …”
Get full text

Curcumin as a Supportive Therapy in Type 2 Diabetic Patients by Anand Seth, Sravya Iyyuni, Saurabh Sharma, Ritu Sethi, Suresh Nath, Michael Imeokparia

“…In the treatment of T2DM, curcumin has demonstrated much potential as an adjunct therapy due to its anti-inflammatory properties and its ability to reduce oxidative stresses within the body. …”
Get full text