Predictive factors for axillary pathological complete response to neoadjuvant therapy in elderly breast cancer patients by Yuying Wang, Rui Wang, Di Lu, Yaling Zeng, Xihui Tu, Shiwei Liu, Purong Zhang

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A New gcrR-Deficient Streptococcus mutans Mutant for Replacement Therapy of Dental Caries by Wenting Pan, Tiantian Mao, Qing-an Xu, Jin Shao, Chang Liu, Mingwen Fan

“…These findings demonstrate that MS-gcrR-def appears to be a good candidate for replacement therapy.…”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

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Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome Model by Emrullah Beyazyıldız, Ferda Alpaslan Pınarlı, Özlem Beyazyıldız, Emine Rümeysa Hekimoğlu, Uğur Acar, Muhammed Necati Demir, Aynur Albayrak, Figen Kaymaz, Güngör Sobacı, Tuncay Delibaşı

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5-aminolevulinic acid in photodynamic therapy used in dermatology as a method of treating acne vulgaris. by Karolina Sacher, Krystyna Zabojska, Aleksandra Cygnarowicz, Mariola Turemka, Negar Hosseinnejad, Aneta Klaudia Wojtas, Mikołaj Biskupski, Urszula Korotko, Kinga Witowska, Aneta Mandziuk

Subjects: “…Acne vulgaris, photodynamic treatment, acid 5-aminolevulini, light therapy, red light.…”
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The effect of continuous positive airway pressure therapy on atrial fibrillation in patients with obstructive sleep apnea by Jiancheng Hu, Siyuan Zuo, Jiahui Qian, Fangfang Cheng, Dengji Wang, Yanyan Deng, Dasheng Lu, Dasheng Lu

“…This review delves into the repercussions of CPAP therapy on AF in OSA patients, exploring potential explanations for the discrepancies observed across existing research endeavors. …”
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Brief Acceptance and Commitment Therapy for Fibromyalgia: Feasibility and Effectiveness of a Replicated Single-Case Design by María Camino Gómez-Pérez, Azucena García-Palacios, Diana Castilla, Irene Zaragozá, Carlos Suso-Ribera

“…In this quasi-experimental, replicated single-case design, we will test the feasibility and effectiveness of a brief acceptance and committed therapy intervention using ecological momentary assessment supported by technology. …”
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Polydeoxyribonucleotide Dermal Infiltration in Male Genital Lichen Sclerosus: Adjuvant Effects during Topical Therapy by Luigi Laino, Silvia Suetti, Isabella Sperduti

“…A group of male patients (n = 28; aged 25 to 65) suffering from LS were observed during topical therapy or subdermal in addition to topical therapy. …”
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HMGB1 Box A gene therapy to alleviate bleomycin-induced pulmonary fibrosis in rats by Rathasapa Patarat, Suchanart Chuaybudda, Sakawdaurn Yasom, Apiwat Mutirangura

“…Previously, a new gene therapy technology using Box A of the HMGB1 plasmid (Box A) was used to reverse cellular senescence and cure liver fibrosis in aged rats. …”
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Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease by Ning-Yi Hsia, Chun-Ju Lin, Chun-Ting Lai, Henry Bair, Cheng-Hsien Chang, Jane-Ming Lin, Yi-Yu Tsai

“…Intravitreal aflibercept was administered as rescue therapy after persistent retinal neovascularization following retinal photocoagulation, periocular triamcinolone, and intravitreal ranibizumab injection. …”
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Epitranscriptomic RNA m6A Modification in Cancer Therapy Resistance: Challenges and Unrealized Opportunities by Mohammad Burhan Uddin, Zhishan Wang, Chengfeng Yang

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Tacrolimus for Remission Induction and Maintenance Therapy in Patients with Ulcerative Colitis: A Retrospective Evaluation Study by Ayumi Ito, Bunei Iizuka, Teppei Omori, Shinichi Nakamura, Katsutoshi Tokushige

“…In this retrospective study, we compared the efficacy of tacrolimus (TAC) or prednisolone (PSL) for maintenance therapy in patients with ulcerative colitis (UC) at remission. …”
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Phage Therapy as a Rescue Treatment for Recurrent <i>Pseudomonas aeruginosa</i> Bentall Infection by Victor Eiferman, Pierre-Adrien Vion, Alexandre Bleibtreu

Subjects: “…phage therapy…”
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Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy by Efstathios Rallis, Vasiliki-Kalliopi Bournia, Constantinos Verros, Alexios Iliopoulos

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Effect of play therapy and storytelling on the anxiety level of hospitalized children: a randomized controlled trial by Fatemeh Abdi, Ali Karamoozian, Mostafa Lotfilou, Fatemeh Gholami, Negin Shaterian, Alireza Abasi Niasar, Ehsan Aghapour, Mohammadamin Jandaghian-Bidgoli

Subjects: “…Play therapy…”
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Impact of Inappropriate Empiric Antimicrobial Therapy on Mortality of Septic Patients with Bacteremia: A Retrospective Study by Saoraya Lueangarun, Amorn Leelarasamee

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Beta Blocker Therapy in Heart Failure Patients with Active Cocaine Use: A Systematic Review by Baldeep K. Mann, Janpreet S. Bhandohal, Mohammad Saeed, Gerald Pekler

“…The use of beta blocker therapy appears to be safe and beneficial in heart failure patients with active cocaine use, although the evidence is not robust. …”
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Vitiligo-like lesions following imatinib mesylate therapy: a case series and review of literature by Neerja Saraswat, Shekhar Neema, Sushil Kumar

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Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy by Yanru Feng, Xintong Pan, Ziqian Li, Yue Li, Ya’nan Sun, Shaokun Yang, Chaoxing He, Yunjie Dang, Lu Huang, Bai Xiang

“…<b>Methods:</b> In this study, we introduce a novel lipid nanoparticle formulation co-delivering hydroxychloroquine (HCQ) and siRNA targeting TNF-α (si<i>TNF-α</i>) using microfluidic technology, marking the first use of such a combination for RA therapy. <b>Results:</b> In LPS-stimulated RAW 264.7 cells, the nanoparticles effectively reduced inflammatory markers. …”
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Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment by Bassel Alsaed, Linh Lin, Jieun Son, Jiaqi Li, Johannes Smolander, Timothy Lopez, Pinar Ö. Eser, Atsuko Ogino, Chiara Ambrogio, Yoonji Eum, Tran Thai, Haiyun Wang, Eva Sutinen, Hilma Mutanen, Hanna Duàn, Nina Bobik, Kristian Borenius, William W. Feng, Behnam Nabet, Satu Mustjoki, Sanna Laaksonen, Benjamin K. Eschle, Michael J. Poitras, David Barbie, Ilkka Ilonen, Prafulla Gokhale, Pasi A. Jänne, Heidi M. Haikala

“…Intratumor heterogeneity is a known cause of targeted therapy resistance and is considered a major factor in treatment failure. …”
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