Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry? by Panagiotis Kanellopoulos, Quanyi Yu, Abouzayed Abouzayed, Ekaterina Bezverkhniaia, Vladimir Tolmachev, Anna Orlova

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Long-Term Therapeutic Effects of ²²⁵Ac-DOTA-E[c(RGDfK)]₂ Induced by Radiosensitization via G2/M Arrest in Pancreatic Ductal Adenocarcinoma by Mitsuyoshi Yoshimoto, Kohshin Washiyama, Kazunobu Ohnuki, Ayano Doi, Miki Inokuchi, Motohiro Kojima, Brian W. Miller, Yukie Yoshii, Anri Inaki, Hirofumi Fujii

“…Biodistribution and therapeutic studies were carried out in BxPC-3-bearing mice. …”
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High Incidence of Refeeding Syndrome during the Transition from F75 to Ready-to-Use Therapeutic Feeds among Children 6 to 59 Months with Severe Acute Malnutrition at the Pediatric Nutritional Unit of Mulago Hospital by Wani Muzeyi, Teddy Ochieng Andra, Lorraine Oriokot, Victor Musiime

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Grupo terapêutico on-line: dispositivo de cuidado para saúde mental de universitários em tempos de pandemia // On-line therapeutic group: care device for the mental health of college students in pandemic times by Rafaella Andrade Vivenzio, Ana Elisa Reis Amorim, Johnatan Martins Sousa, Marciana Gonçalves Farinha

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Cannabis mythology: the process of shaping from experience in Nakhon Si Thammarat, Thailand by Fareeda Jeh-oh, Attanan Tachopisalwong

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Empirical Study on Emotional Perception and Restorative Effects of Suzhou Garden Landscapes: Text Mining and Statistical Analysis by Zhenyu Zhang, Xiaomeng Wang, Mu Jiang

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Unveiling the role of lncRNA ERDR1 in immune cell regulation by Aihua Shu, Xu Tian, Jie Yue, Yuxia Jiang, Yifei Liu

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Cancer stem-like cells stay in a plastic state ready for tumor evolution by Jiali Xu, Houde Zhang, Zhihao Nie, Wenyou He, Yichao Zhao, Zhenhui Huang, Lin Jia, Zhiye Du, Baotong Zhang, Siyuan Xia

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Investigating resistance to 5-Azacytidine and Venetoclax in PDX models of MDS/AML by Petra Bašová, Lubomír Minařík, Lubomír Minařík, Silvia Carina Magalhaes-Novais, Jana Balounová, Zuzana Zemanová, Tatiana Aghová, Martin Špaček, Anna Jonášová, Kristýna Gloc Pimková, Jan Procházka, Radislav Sedláček, Tomáš Stopka, Tomáš Stopka

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Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer by Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chenlin Sui, Hengjie Cao, Dune Su, Lianwei Xu, Honghong Wang

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Gut microbiota-derived metabolites and chronic inflammatory diseases by Alejandra Vargas, Benjamin L. Robinson, Kevin Houston, Ana Rosa Vilela Sangay, Michael Saadeh, Steve D’Souza, David A. Johnson

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Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization by Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani

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Plasma exchange alone versus combination with intravenous immunoglobulin/methylprednisolone pulse therapy in severe systemic rheumatic diseases: a retrospective study by Jing Guo, Jing Guo, Jing Guo, Shuiwen Li, Shuiwen Li, Shuiwen Li, Hao Xu, Hao Xu, Hao Xu, Xinxin Wang, Xinxin Wang, Xinxin Wang, Weiyuan Luo, Weiyuan Luo, Weiyuan Luo, Jie Sun, Jie Sun, Jie Sun, Jianhua Li, Jianhua Li, Jianhua Li, Zhu Chen, Zhu Chen, Zhu Chen, Guiyang Lu, Guiyang Lu, Guiyang Lu, Xiaolong Huang, Xiaolong Huang, Xiaolong Huang, Shiju Chen, Shiju Chen, Yaogui Ning, Yaogui Ning, Yaogui Ning

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Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment by Liang Peng, Yi Lai, Baodi Cao

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Circ_0001084/miR-181c-5p/PTPN4 Axis Mitigates Cardiomyocyte Injury by Modulating the TLR4/NF-κB Pathway: Insights into Therapeutic Potential for Myocardial Reperfusion Injury by Deng H, Fan Q, Huang L, Ouyang W, Zhu W

“…These findings offer insights into the molecular mechanisms of myocardial I/R injury and potential therapeutic targets in ischemic heart disease.Keywords: Myocardial, Circ_0001084/miR-181c-5p/PTPN4 axis, Cardiomyocyte hypoxia, Reoxygenation, TLR4/NF-κB pathway…”
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Safety and efficacy of the therapeutic DNA-based vaccine VB10.16 in combination with atezolizumab in persistent, recurrent or metastatic HPV16-positive cervical cancer: a multicenter, single-arm phase 2a study by Hannelore Denys, Frederik Marmé, Frederic Forget, Lukas Rob, Pawel Blecharz, Kristina Lindemann, Peter Hillemanns, Linn Wölber, Theresa Link, Jean-Francois Baurain, Mariusz Bidziński, Linn Woelber, Michal ZikÁN, Josef Chovanec, Christian Dannecker, Stéphanie Henry, Hannelore G Denys, Velko Minchev, Anders Rosholm, Kaja C G Berg, Roberto S Oliveri, Marchela Koleva, Bozhil Robev

“…We investigated the safety, efficacy, and immunogenicity of the therapeutic DNA-based vaccine VB10.16 combined with the immune checkpoint inhibitor atezolizumab in patients with human papillomavirus (HPV)16-positive r/m cervical cancer.Patients and methods This multicenter, single-arm, phase 2a study (NCT04405349, registered 26 May 2020) enrolled adult patients with persistent, r/m HPV16-positive cervical cancer. …”
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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate cancer by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

“…However, chemotherapy resistance typically develops after an initial period of therapeutic efficacy. Increasing evidence indicates that cancer stem cells confer chemotherapy resistance via exosomes. …”
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Therapeutic Efficacy of <i>Lavandula dentata</i>’s Oil and Ethanol Extract in Regulation of the Neuroinflammation, Histopathological Alterations, Oxidative Stress, and Restoring Balance Treg Cells Expressing FoxP3+ in a Rat Model of Epilepsy by Aziza Antar, Eman S. Abdel-Rehiem, Areej A. Al-Khalaf, Abdelaziz S. A. Abuelsaad, Mohamed Abdel-Gabbar, Gaber M. G. Shehab, Ayman M. Abdel-Aziz

“…Furthermore, the role of oxidative stress and neuroinflammatory responses in epilepsy and the limitations of current AEDs necessitate exploring alternative therapeutic options. Medicinal plants, e.g., <i>Lavandula dentata</i> L., are rich in phenolic compounds and may provide neuroprotective and anti-inflammatory benefits. …”
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SAP30, a novel autophagy regulatory gene in neuroblastoma by Anup S. Pathania, Anjana Murugan, Areem Zahid, Haritha Chava, Don W. Coulter, George A. Calin, Kishore B. Challagundla

Subjects: “…MT: Novel therapeutic targets and biomarker development special issue…”
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Production of antibodies and antibody fragments containing non-natural amino acids in Escherichia coli by Jacquelyn Blake-Hedges, Dan Groff, Wilson Foo, Jeffrey Hanson, Elenor Castillo, Miao Wen, Diana Cheung, Mary Rose Masikat, Jian Lu, Young Park, Nina Abi Carlos, Hans Usman, Kevin Fong, Abigail Yu, Sihong Zhou, Joyce Kwong, Cuong Tran, Xiaofan Li, Dawei Yuan, Trevor Hallam, Gang Yin

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