Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics by Haruno Oku, BS, Saki Yoshida, BS, Takumi Hotta, BS, Hirohito Muroi, BS, Keizo Fukushima, PhD, Kei Irie, PhD, Tatsuya Hirano, BS, Yoshimitsu Shimomura, MD, Takayuki Ishikawa, MD, PhD, Hiroaki Ikesue, PhD, Nobuyuki Muroi, PhD, Tohru Hashida, PhD, Nobuyuki Sugioka, PhD

Subjects: Get full text

Editorial: Updates on the management of glioblastoma by Dorota Lubanska, Dorota Lubanska, Sameh Elmorsy Hassan, Lisa A. Porter, Lisa A. Porter, Lisa A. Porter, Lisa A. Porter, Mohamed A.R. Soliman, Mohamed A.R. Soliman

Subjects: Get full text

Vécus croisés de médecins et de patients. Le cas de l’annonce diagnostique de la maladie rare by Séverine Colinet, Céline Avenel

Subjects: Get full text

Inspecting for positive outcomes by Bryan Livingstone

Subjects: “…therapeutic residential child care…”

Endovascular treatment of penetrating nail gun injury of the cervical spine and vertebral artery: a case report by Alexei Christodoulides, Scott Mitchell, Bradley N. Bohnstedt

Subjects: Get full text

Tackling ALT-positive neuroblastoma: is it time to redefine risk classification systems? A systematic review with IPD meta-analysis by Marta Avinent-Pérez, Frank Westermann, Samuel Navarro, Amparo López-Carrasco, Rosa Noguera

Subjects: Get full text

Case report: Multiple cryotherapy sessions in localized Darier's disease: a rare clinical presentation and literature review by Yansi Lyu, Bin Wang, Lyuxin Guan, Li Ma, Hao Li

Subjects: Get full text

Editorial: Non-coding RNAs in breast cancer, volume II by Wenwen Zhang, Naoyuki Kataoka, Xiaoxiang Guan, Xiaoxiang Guan

Subjects: Get full text

Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics by Andong Guo, Andong Guo, Chenrui Wu, Jishuang Cao, Kejia Zhu, Kejia Zhu, Sentai Ding, Sentai Ding

Subjects: Get full text

Preclinical Efficacy and Proteomic Prediction of Molecular Targets for s-cal14.1b and s-cal14.2b Conotoxins with Antitumor Capacity in Xenografts of Malignant Pleural Mesothelioma by Angélica Luna-Nophal, Fernando Díaz-Castillo, Vanessa Izquierdo-Sánchez, Jesús B. Velázquez-Fernández, Mario Orozco-Morales, Luis Lara-Mejía, Johana Bernáldez-Sarabia, Noemí Sánchez-Campos, Oscar Arrieta, José Díaz-Chávez, Jorge-Ismael Castañeda-Sánchez, Alexei-Fedorovish Licea-Navarro, Saé Muñiz-Hernández

Subjects: Get full text

MiCML: a causal machine learning cloud platform for the analysis of treatment effects using microbiome profiles by Hyunwook Koh, Jihun Kim, Hyojung Jang

Subjects: Get full text

Therapeutic effect of computed tomography-guided dorsal root ganglion pulsed radiofrequency regulation combined with platelet-rich plasma injection on postherpetic neuralgia: A retrospective study by Zhongwei Wang, Jing Chen, Xiaona Guo, Yan Lin, Weipeng Ge, Yunchao Chu

Get full text

A miR-activated hydrogel for the delivery of a pro-chondrogenic microRNA-221 inhibitor as a minimally invasive therapeutic approach for articular cartilage repair by Shan An, Claudio Intini, Donagh O'Shea, James E. Dixon, Yiran Zheng, Fergal J. O'Brien

“…These results provide evidence of the potential of the miR-activated hydrogel as a minimally invasive therapeutic strategy for articular cartilage repair.…”
Get full text

GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

“…Fusion proteins and immunoconjugates represent an innovative therapeutic approach to specifically deliver a deadly payload to target cells. …”
Get full text

Treatment Algorithm for Chronic Idiopathic Constipation and Constipation-Predominant Irritable Bowel Syndrome Derived from a Canadian National Survey and Needs Assessment on Choices of Therapeutic Agents by Yvonne Tse, David Armstrong, Christopher N. Andrews, Alain Bitton, Brian Bressler, John Marshall, Louis W. C. Liu

“…In a national survey, we aimed to evaluate (1) Canadian physician practice patterns in the utilization of therapeutic agents listed in the new ACG and AGA guidelines; (2) physicians satisfaction with these agents for their CIC and IBS-C patients; and (3) the usefulness of these new guidelines in their clinical practice. …”
Get full text

Inhibition of the anti-apoptotic protein BCL2 in EML4-ALK cell models as a second proposed therapeutic target for non-small cell lung cancer. by Richard Junior Zapata Dongo, Diletta Fontana, Luca Mologni, Juan Enrique Faya Castillo, Stefany Fiorella Infante Varillas

“…On the other hand, overexpression of BCL2, a protein involved in cell death regulation, has been observed in NSCLC and is considered a potential therapeutic target. In this study, we propose to inhibit BCL2 as a secondary therapeutic target in EML4-ALK cell models to overcome resistance caused by ALK mutations. …”
Get full text

Inhibition of the anti-apoptotic protein BCL2 in EML4-ALK cell models as a second proposed therapeutic target for non-small cell lung cancer by Richard Junior Zapata Dongo, Diletta Fontana, Luca Mologni, Juan Enrique Faya Castillo, Stefany Fiorella Infante Varillas

Get full text

Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study by Tianzhi Wu, Dandan Liu, Shangqin Liu, Hui Xiao, Bei Xiong, Yi Zhou, Yafen Xiong, Qin Cui, Jiang Wu, Minghui Liu, Hongli Liu, Yiming Li, Meixin Wang, Xueqin Bao, Ye Li, Fuling Zhou

“…Bortezomib-based chemotherapy plus therapeutic plasmapheresis (TPP) with 4% human ALB solution was assessed for three years in patients with MM aged >18 years, with AKI according to the Kidney Disease Improving Global Outcomes criteria, and without previous renal impairment from other causes. …”
Get full text

Recovery time and predictors of severe acute malnutrition in children aged 6-59 months via an outpatient therapeutic program in Borena zone: A prospective cohort study. by Girma Tenkolu Bune, Abuna Mohammed, Samrawit Hailu, Eden Ashenafi

“…<h4>Objective</h4>This study aims to assess the time to recovery and its predictors among children aged 6-59 months with SAM admitted to the Outpatient therapeutic program in the Borena zone, Oromia region, Southern Ethiopia in 2023.…”
Get full text

Urinary exosomal miRNA-451a can be used as a potential noninvasive biomarker for diagnosis, reflecting tubulointerstitial damage and therapeutic response in IgA nephropathy by Qiong Zhang, Yan Zhao, Yankun Luo, Songjia Guo, Haizhu Hou, Xiaoli Han, Yun Zhou

Subjects: Get full text