Efficacy of Intravenous Versus Oral Administration of Levocarnitine in Maintenance Hemodialysis Patients: A Randomized Controlled Trial Investigating Therapeutic Approaches to Renal Anemia by Sadia Rehman, Muhammad Farhan, Santosh Kumar, Muhammad Raza Sarfraz, Asma Naveed, Muhammad Tassaduq Khan, Hiya Huq

Get full text

Therapeutic Decision Making in Acute Stroke due to Carotid Artery Dissection: A Potential Role for Percutaneous Vascular Intervention following Intravenous Thrombolysis by J. B. Lewis, Á. Merwick, R. Ó. Laoide, A. O'Hare, C. McGuigan

Get full text

Molecular Epidemiology, Drug-Resistant Variants, and Therapeutic Implications of Hepatitis B Virus and Hepatitis D Virus Prevalence in Nigeria: A National Study by Oludare ‘Sunbo Adewuyi, Muhammad Shakir Balogun, Hirono Otomaru, Alash’le Abimiku, Anthony Agbakizu Ahumibe, Elsie Ilori, Que Anh Luong, Nwando Mba, James Christopher Avong, John Olaide, Oyeladun Okunromade, Adama Ahmad, Afolabi Akinpelu, Chinwe Lucia Ochu, Babatunde Olajumoke, Haruka Abe, Chikwe Ihekweazu, Adetifa Ifedayo, Michiko Toizumi, Hiroyuki Moriuchi, Katsunori Yanagihara, Jide Idris, Lay-Myint Yoshida

Get full text

Efficient Therapeutic Function and Mechanisms of Human Polyclonal CD8+CD103+Foxp3+ Regulatory T Cells on Collagen-Induced Arthritis in Mice by Juan Sun, Yiming Yang, Xiaona Huo, Beibei Zhu, Zhenhua Li, Xueyu Jiang, Rufeng Xie, Li Gao, Ying Sun, Huahua Fan, Yongming Zhu, Jie Yang

“…To investigate the potential therapeutic effect in a rheumatoid arthritis model of stable human CD8+ regulatory T cells (hCD8+Tregs) induced by TGF-β1 and rapamycin (RAPA) in vitro. …”
Get full text

The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment by Yanchao Luan, Chao Liang, Qingsong Han, Xueqin Zhou, Na Yang, li Zhao

“…Furthermore, the IC50 values for cisplatin, paclitaxel, and docetaxel were notably elevated in the high-risk group, indicating that these medications could potentially provide therapeutic advantages for this particular group. Finally, we determined that knockdown CDKN3 inhibited the proliferation and metastasis of LUAD cells. …”
Get full text

NEIL3 Mediates Lung Cancer Progression and Modulates PI3K/AKT/mTOR Signaling: A Potential Therapeutic Target by Hongbo Huang, Qingwang Hua

Get full text

Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors by Shudong Lin, Guanghua Zhu, Juan Xie, Xuanwei Wen, Limin Deng, Sijing Li, Guozhi Liu, Feiyan Wang, Shuangxi Chen, Zijian Xiao

“…Conclusion Our research findings demonstrate that BDMC exerts therapeutic effects in a mouse model of CAA established through chronic treatment involving five vascular risk factors.…”
Get full text

Evaluating the nutritional, therapeutic, and economic potential of Tetragonia decumbens Mill.: A promising wild leafy vegetable for bio-saline agriculture in South Africa by Sogoni Avela, Jimoh Muhali Olaide, Ngxabi Sihle, Kambizi Learnmore, Laubscher Charles Petrus

Get full text

Efficacy, safety, and therapeutic drug monitoring of polymyxin B sulfate and colistin sulfate in critically ill patients: a real-world retrospective study by Yijing Zhang, Chuhui Wang, Jiaojiao Chen, Chuqi Bai, Dan Sun, Yulan Qiu, Mengmeng Teng, Yalin Dong

Subjects: Get full text

Correlation between Therapeutic Efficacy of CD34+ Cell Treatment and Directed In Vivo Angiogenesis in Patients with End-Stage Diffuse Coronary Artery Disease by Tien-Hung Huang, Cheuk-Kwan Sun, Yi-Ling Chen, Pei-Hsun Sung, Chi-Hsiang Chu, Mel S. Lee, Yuan-Ping Lin, Hon-Kan Yip, Fan-Yen Lee

“…This study was aimed at testing the association between the therapeutic efficacy of CD34+ cell treatment in patients with end-stage diffuse coronary artery disease as reflected in angiographic grading and results of directed in vivo angiogenesis assay (DIVAA) on their isolated peripheral blood mononuclear cell- (PBMC-) derived endothelial progenitor cells (EPCs). …”
Get full text

In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection by Yuta Suzuki, Takayuki Miyazaki, Yoko Ida, Tatsuya Suzuki, Yumi Itoh, Shuto Nakao, Keita Kondo, Kenji Kubara, Keisuke Nishioka, Hiroki Muto, Ryuji Watari, Toshifumi Hirayama, Dai Kakiuchi, Shinya Sato, Satoshi Inoue, Yoshifumi Uemoto, Yohei Mukai, Atsushi Hoshino, Toru Okamoto, Junji Matsui

Subjects: Get full text

CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA by Zachary F. Mandell, Andrew Ujita, Jordana Henderson, Anthony Truong, Coleen Vo, Farinaz Rezvani, Nona Abolhassani, Alexandre Lebedev, Chunping Xu, Inna Koukhareva, Stephanie Ramos, Kate Broderick, Benjamin Hudson, Jeff Coller

Subjects: Get full text

Ferroptosis in thyroid cancer: mechanisms, current status, and treatment by Wenzhi Tian, Wenzhi Tian, Xi Su, Chenchen Hu, Dong Chen, Peng Li

Subjects: Get full text

The Ecosystem of AI-Driven Robotics in Pediatric Neurorehabilitation by Tole Sutikno, Lina Handayani

Subjects: Get full text

Minimally Invasive Stabilization with Percutaneous Screws Fixation of APC-3 Pelvic Ring Injury by Beom-Soo Kim, Jong-Keon Oh, Jae-Woo Cho, Do-Hyun Yeo, Jun-Min Cho

Subjects: Get full text

Effects of a therapeutic suit based on myofascial meridians on postural control and balance in children with cerebral palsy: a multiple-baseline, single-subject study by Thalita Karla Flores Cruz, Deisiane Oliveira Souto, Rafhael Guimarães Capuchinho, Arthur Felipe Barroso de Lima, Amanda Aparecida Alves Cunha Nascimento, Ianara Pereira Silva, Patrícia Aparecida Neves Santana, Lia Constantino Criscoullo, Vitor Geraldi Haase, Vitor Geraldi Haase

Subjects: Get full text

High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis by Yitong Li, Tingting Feng, Qinghong Wang, Yue Wu, Jue Wang, Wenlong Zhang, Qi Kong

Subjects: Get full text

FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2 by Kongyan Zhang, Fei Zhang, Jiahe Wang

Subjects: Get full text

Beyond Immunuhistochemistry: Molecular Insights Into Round Cell Soft Tissue Tumors by Prashanth Kumar Madoori, Sujatha Tejavat

Subjects: Get full text

Synergistic effect of blocking cancer cell invasionrevealed by computer simulations by Kazuhisa Ichikawa

Subjects: Get full text