FOXP3 as a prognostic marker and therapeutic target in immunogenic cell death modulation for clear cell renal cell carcinoma by Jian Chen, Cheng Zhu, Yan He, Liping Huang, Weizhuo Wang, Shuaishuai Huang

“…Targeting FOXP3 and other ICD pathways could enhance treatment efficacy in ccRCC, providing a foundation for ICD-based therapeutic strategies. Evaluating ICD patterns in ccRCC may guide patient-specific interventions, paving the way for improved management of this aggressive cancer.…”
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Therapeutic Potential of <i>Lappula patula</i> Extracts on Germline Development and DNA Damage Responses in <i>C. elegans</i> by Qinghao Meng, Anna Hu, Weiyu Xiao, Robert P. Borris, Hyun-Min Kim

“…Further studies are needed to explore the therapeutic potential of these compounds in clinical settings.…”
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Therapeutic effects of resveratrol and β-carotene on L-arginine-induced acute pancreatitis through oxidative stress and inflammatory pathways in rats by Arzu Gezer, Hilal Üstündağ, Mustafa Özkaraca, Ebru Karadağ Sari, Cihan Gür

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SLC7A11 is a potential therapeutic target and prognostic biomarker correlated with immune cell infiltration in cervical cancer by Mutangala Muloye Guy, Tingting Bian, Longyun Sun, Yiping Hao, Xinlin Jiao, Wenjing Zhang, Teng Zhang, Baoxia Cui

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Systematic multiomics analysis and in vitro experiments suggest that ITGA5 could serve as a promising therapeutic target for ccRCC by Xiangxian Che, Xi Tian, Zhenda Wang, Shuxuan Zhu, Shiqi Ye, Yue Wang, Yihan Chen, Yiyun Huang, Aihetaimujiang Anwaier, Peifeng Yao, Yijia Chen, Keting Wu, Yifei Liu, Wenhao Xu, Hailiang Zhang, Dingwei Ye

“…Further, we predicted immune infiltration and medication sensitivity regulation by ITGA5 and proposed a joint use of ITGA5 inhibitors and anti-angiogenetic drugs as a potential potent therapeutic strategy.…”
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Should we consider microbiota-based interventions as a novel therapeutic strategy for schizophrenia? A systematic review and meta-analysis by Lucas Hassib, Alexandre Kanashiro, João Francisco Cordeiro Pedrazzi, Bárbara Ferreira Vercesi, Sayuri Higa, Íris Arruda, Yago Soares, Adriana de Jesus de Souza, Alceu Afonso Jordão, Francisco Silveira Guimarães, Frederico Rogério Ferreira

“…Due to this multifactorial etiology and neurobiology, leading to a wide heterogeneity of symptoms and clinical presentations, current antipsychotic treatments face challenges, underscoring the need for novel therapeutic approaches. Recent studies have revealed differences in the gut microbiome of individuals with schizophrenia compared to healthy controls, establishing an intricate link between this disorder and gastrointestinal health, and suggesting that microbiota-targeted interventions could help alleviate clinical symptoms. …”
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Clinical predictors of therapeutic laparotomy in anterior abdominal stab injuries: a multicenter study from low-income institutions in Ethiopia by Segni Kejela, Abel Hedato, Yeabsera Mekonnen Duguma, Meklit Solomon Gebremariam

“…Purpose Despite the high incidence of abdominal stab injuries, the rate of nontherapeutic laparotomies and the predictors of therapeutic laparotomies have rarely been studied in low-income settings. …”
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Association of Toll-Like Receptor Signaling and Reactive Oxygen Species: A Potential Therapeutic Target for Posttrauma Acute Lung Injury by Meng Xiang, Janet Fan, Jie Fan

“…This paper summarizes some novel mechanisms underlying HS-primed lung inflammation focusing on the role of TLRs and ROS, and therefore suggests a new therapeutic target for posttrauma ALI.…”
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Therapeutic Community (TC) pada Residen Penyalah Guna Narkoba di Panti Social Marsudiputra Dharmapala Inderalaya Sumatera Selatan by Syarifuddin Gani

“…Terapi dan rehalibitasi korban penyalahgunaan narkoba, merupakan sistem pelayanan terpadu dengan menggunakan Therapeutic Community (TC)  merupakan treatment yang menggunakan pendekatan psikososial, yaitu bersama-sama dengan mantan pengguna narkoba lainnya mereka hidup dalam satu lingkungan dan saling membantu untuk mencapai kesembuhan. …”
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Optimization strategy for the early therapeutic intervention of bronchoalveolar lavage for preventing Mendelson syndrome in a geriatric patient before general anesthesia by Satish Kumar Mishra, Pitchi Chandrakanth Reddy, Shalendra Singh, Gaurav Pandey, Narayanan Subramanian

“…The patient’s clinical presentation and application of therapeutic bronchoalveolar lavage as a novel intervention are discussed. …”
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Nuclear factor Erythroid 2-related factor (Nrf2): A potential therapeutic target for oral cancer - Molecular insights by Kaviyarasi Renu, Vishnu Priya Veeraraghavan, Abilash Valsala Gopalakrishnan

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An adenoviral vector encoding an inflammation-inducible antagonist, HMGB1 Box A, as a novel therapeutic approach to inflammatory diseases by Kari Ann Shirey, John Joseph, Lynda Coughlan, Haye Nijhuis, Alan W. Varley, Jorge C. G. Blanco, Stefanie N. Vogel

“…We have engineered a non-replicative AdV vector that produces HMGB1 Box A, an antagonist of HMGB1-induced inflammation, under the control of an endogenous complement component C3 (C3) promoter sequence, that is inducible by LPS and influenza in vitro and ex vivo in macrophages (Mϕ) and protects mice and cotton rats therapeutically against infection with mouse-adapted and human non-adapted influenza strains, respectively, in vivo. …”
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A panel of cancer testis antigens in squamous cell carcinoma of the lung, head and neck, and esophagus: implication for biomarkers and therapeutic targets by Lin Li, Xin Zhang, Jiayao Yan, Jingyi Guo, Fangcen Liu, Xiao Wei, Qin Liu, Kongcheng Wang, Baorui Liu

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Super-enhancer-driven SLCO4A1-AS1 is a new biomarker and a promising therapeutic target in glioblastoma by Yibo Wu, Fang Li, Chen Yang, Xuehai Zhang, Zhiwei Xue, Yanfei Sun, Xiaoying Lin, Xuemeng Liu, Zhimin Zhao, Bin Huang, Qibing Huang, Xingang Li, Mingzhi Han

“…In conclusion, this study revealed that SE-driven SLCO4A1-AS1 may be a potential therapeutic target in GBM.…”
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Real-Time Fluorescence Imaging Using Indocyanine Green to Assess Therapeutic Effects of Near-Infrared Photoimmunotherapy in Tumor Model Mice by Adrian Rosenberg, Daiki Fujimura MD, Ryuhei Okada MD, PhD, Aki Furusawa PhD, Fuyuki Inagaki MD, PhD, Hiroaki Wakiyama MD, PhD, Takuya Kato MD, PhD, Peter L. Choyke MD, Hisataka Kobayashi MD, PhD

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Therapeutic Gardens for Oncology Hospital. Architectural Students Proposals to Alleviate Stress in Healthcare Environment Created During the COVID-19 Pandemic by TROJANOWSKA Monika

Subjects: “…therapeutic gardens…”
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In vivo evaluation of focused ultrasound ablation surgery (FUAS)-induced coagulation using echo amplitudes of the therapeutic focused ultrasound transducer by Yufeng Zhou, Xiaobo Gong, Yaqing You

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Therapeutic Effect of Upper Limb Intelligent Rehabilitation Robot and Routine Rehabilitation Combination on Upper Extremities'Motor Function of Stroke Patients by Dongyan XU, Rujin TIAN, Jue LIU, Gang LIU, Yulian ZHU

“…Objective:To observe the therapeutic effect of upper limb intelligent rehabilitation robot and routine rehabilitation combination on upper extremities'motor function of stroke patients.Methods:30 stroke patients accorded with inclusive criteria were selected, all patients received routine rehabilitation for two weeds, each time for twenty minutes, once a day and five days each week. …”
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microRNAs as a New Mechanism Regulating Adipose Tissue Inflammation in Obesity and as a Novel Therapeutic Strategy in the Metabolic Syndrome by Qian Ge, Sonia Brichard, Xu Yi, QiFu Li

“…This review will focus on the implication of miRNAs in white AT inflammation in obesity, and will also highlight the potential of miRNAs as targets for therapeutic intervention in MS as well as the challenges lying in miRNA-targeting therapeutics.…”
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Identification and validation of CDK1 as a promising therapeutic target for Eriocitrin in colorectal cancer: a combined bioinformatics and experimental approach by Jiemiao Shen, Xing Gong, Haili Ren, Xia Tang, Hairong Yu, Yilu Tang, Shen Chen, Minghui Ji

“…Eriocitrin, a potential CDK1 inhibitor derived from TCM, highlights a promising new therapeutic strategy for CRC treatment.…”
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