Diagnostic and Therapeutic Laparoscopy for Abdominal Trauma: A Single Surgeon’s Experience at a Level I Trauma Center by Hancheol Jo, Dong Hun Kim

“…The number of surgeons using laparoscopy as a diagnostic and therapeutic tool in abdominal trauma patients is increasing, whereas open conversion is becoming less common. …”
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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

“…Its expression is closely associated with immune-related genes and may serve as both a prognostic biomarker and a therapeutic target. These findings underscore SOX2's potential in regulating immune checkpoints and enhancing cancer immunotherapy.…”
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Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning by V. Vigna, T. F. G. G. Cova, A. A. C. C. Pais, E. Sicilia

“…Scientific Contribution: The proposed machine learning (ML) approach predicts the ability of transition metal-based complexes to absorb light in the UV–vis therapeutic window, a key trait for phototherapeutic agents. …”
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Feasibility, Usability, and Pilot Efficacy Study of a Software-Enabled, Virtual Pulmonary Rehabilitation with Remote Therapeutic Monitoring by Flynn S, Mosher CL, Cornelison S, Rao E, Metzler KA, Pu W, Davies J, Paladenech C, Doyle D, MacIntyre N, Ohar J

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Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels by Itsuro Kazama

“…Based on the recent in vitro evidence that revealed the pharmacological properties of the channels, the most recent studies have revealed novel therapeutic implications of targeting the lymphocyte Kv1.3-channels for the treatment of renal diseases.…”
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Therapeutic Effect of Stem Cells on Male Infertility in a Rat Model: Histological, Molecular, Biochemical, and Functional Study by Sally S. Mohammed, Mona F. Mansour, Noha A. Salem

“…In recent years, the era of stem cell applications becomes a promising point as a possible therapeutic agent in male infertility. This study is aimed at evaluating the therapeutic effects of stem cells at histological, molecular, biochemical, and functional levels in a methotrexate-induced testicular damage model. …”
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The potential therapeutic role of berberine in treating epilepsy focusing on temporal lobe epilepsy: State of art and ongoing perspective by Bshra A. Alsfouk, Hayder M. Al-Kuraishy, Ali K. Albuhadily, Ali I. Al-Gareeb, Ahmed M. Abdelaziz, Athanasios Alexiou, Marios Papadakis, Mubarak Alruwaili, Gaber El-Saber Batiha

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Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo by Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

“…However, the currently available treatments could only relieve symptoms. Novel therapeutic targets are urgently needed. Several previous studies mentioned that protein tyrosine phosphatase 1B (PTP1B) acted as a negative regulator of the insulin signal pathway and played a significant role in the inflammation process. …”
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Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions by Hyeon-Jeong Hwang, Youngsang Nam, Chanhee Jang, Eun La Kim, Eun Seo Jang, Yeo Jin Lee, Seoung Rak Lee

“…Cancer remains a significant medical challenge, necessitating the discovery of novel therapeutic agents. Ribosomally synthesized and post-translationally modified peptides (RiPPs) from plants have emerged as a promising source of anticancer compounds, offering unique structural diversity and potent biological activity. …”
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Utilizing thiol-protected bimetal nanoclusters to enhance the therapeutic potential of seaweed bioactive compounds in oral cancer treatment by Vinitha Packirisamy

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The Effect of Diaphragmatic Breathing as a Complementary Therapeutic Strategy in Stress of Children and Teenagers 6–18 Years Old by Pelagia Tsakona, Ioannis Kitsatis, Thomas Apostolou, Ourania Papadopoulou, Alexandra Hristara-Papadopoulou

“…Conclusions: DB can effectively contribute on its own or in combination with other therapeutic methods to improving physiological and psychological indicators in the pediatric population. …”
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Unveiling new therapeutic horizons in rheumatoid arthritis: an In-depth exploration of circular RNAs derived from plasma exosomes by Guoqing Li, Hongyi Chen, Jiacheng Shen, Yimin Ding, Jingqiong Chen, Yongbin Zhang, Mingrui Tang, Nan Xu, Yuxuan Fang

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Challenging therapeutic management of visceral leishmaniasis (L. Infantum) in a patient with thymoma: Case report with literature review by Serena Vita, Tommaso Ascoli Bartoli, Andrea Mariano, Gaetano Maffongelli, Laura Scorzolini, Angela Corpolongo, Maria Virginia Tomassi, Silvia Rosati, Francesca Faraglia, Claudia Palazzolo, Nazario Bevilacqua, Maria Letizia Giancola, Antonella Vulcano, Lorenzo Zammarchi, Alessandra D'Abramo, Emanuele Nicastri

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Therapeutic Angiogenesis Using Basic Fibroblast Growth Factor in Combination with a Collagen Matrix in Chronic Hindlimb Ischemia by Jianyin Zhou, Yilin Zhao, Jinling Wang, Sheng Zhang, Zhengjin Liu, Maochuan Zhen, Yun Liu, Pingguo Liu, Zhenyu Yin, Xiaomin Wang

“…Although therapeutic angiogenesis by angiogenic cytokines is a feasible strategy to improve regional blood flow in ischemic regions, the optimal delivery mode needs to be established. …”
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Brain Stimulation Techniques in Research and Clinical Practice: A Comprehensive Review of Applications and Therapeutic Potential in Parkinson’s Disease by Ata Jahangir Moshayedi, Tahmineh Mokhtari, Mehran Emadi Andani

“…This review underscores the potential of brain stimulation as a vital therapeutic tool in managing PD, paving the way for enhanced treatment strategies and improved patient outcomes.…”
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Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma by Hongbing Cheng, Xiao Meng, Yanhua Zhang, Pu Wang, Yucheng Lu

“…These findings not only improve our understanding of LGG biology but also provide scientific evidence for developing potential therapeutic strategies targeting CDKN3.…”
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Diagnostic and therapeutic recommendations for chronic pancreatitis.... by Roland Kadaj-Lipka, Michał Lipiński, Krystian Adrych, Marek Durlik, Anita Gąsiorowska, Mirosław Jarosz, Grażyna Jurkowska, Ewa Małecka-Panas, Grzegorz Oracz, Mariusz Rosołowski, Barbara Skrzydło-Radomańska, Renata Talar-Wojnarowska, Grażyna Rydzewska

“…This article describes the latest diagnostic and therapeutic recommendations in chronic pancreatitis, developed by the Working Group of the Polish Society of Gastroenterology and the Polish Pancreas Club. …”
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Comparing the Therapeutic Impact of Strain-Counterstrain and Exercise on Low Back Myofascial Pain Syndrome: A Randomized Trial by Koura GMR, Elshiwi AMF, Selim MN, Asiri AAM, Alqahtani RHJ, Elimy DA, Alshehri MA, Alnakhli HH, Assiri SM, Ahmad F, Ahmad I

“…Ghada Mohamed Rashad Koura,1 Ahmed Mohamed Fathi Elshiwi,2 Mohamed Naeem Selim,3 Amani Abdu Mohammed Asiri,4 Reem Hadi Jowaied Alqahtani,5 Doaa Ayoub Elimy,6 Mohammed Abdullah Alshehri,7 Hani Hassan Alnakhli,1 Sultan Mofreh Assiri,8 Fuzail Ahmad,9 Irshad Ahmad1 1Program of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, 61421, Saudi Arabia; 2Consultant & Head of Physical Therapy Department, Saudi German Hospital, Aseer, Saudi Arabia; 3Basic Sciences Department, Faculty of Physical Therapy, Beni Suef University, Beni Suef, Egypt; 4Physical Therapy Department, Saudi German Hospital, Aseer, Saudi Arabia; 5Eradh Physical Therapy Center, Aseer, Saudi Arabia; 6Basic Sciences Department, Faculty of Physical Therapy, Cairo University, Cairo, Egypt; 7Department of Physiotherapy, Abha International Private Hospital, Abha, Saudi Arabia; 8Department of Physical Therapy, Muhayel General Hospital, Asir Health Affairs, Ministry of Health, Abha, Saudi Arabia; 9Respiratory Care Department, College of Applied Sciences, Almaarefa University, Dirirya, Riyadh, Saudi ArabiaCorrespondence: Irshad Ahmad, Email iabdulhamed@kku.edu.saBackground: Background: Strain-Counterstrain (SCS) therapy is a manual therapeutic technique used to treat myofascial pain by addressing tender points through passive positioning. …”
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Inflammasome-targeted therapy for oral cancer: Highlighting NLRP3 inflammasome as a promising clinical therapeutic target by Geetha Shanmugam

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Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets by Yuepeng An, Fu Zhao, Hongling Jia, Siyu Meng, Ziwei Zhang, Shuxiao Li, Jiusi Zhao

“…These findings contributed to the development of novel prognostic models for melanoma and shed light on research directions concerning melanoma metastasis mechanisms and therapeutic targets.…”
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