Transurethral Water Vapor Ablation: Potential for a Novel Prostate Cancer Management Strategy by Warlick CA, Spilseth BD, Dixon CM

“…Results of this feasibility study support further exploration of this new therapeutic procedure and the opportunity it may offer to men to manage their localized prostate cancer through surveillance and additional therapy as needed.…”
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Efficacy of the internet-based intervention “Cultivating our resilience” (CORE) for improving resilience and coping strategies in university students: A randomized controlled trial... by Rocio Herrero, Marvin Franke, Dennis Görlich, Azucena Garcia-Palacios, Rosa Baños, Corinna Jacobi, Thomas Berger, Michael P. Schaub, Tobias Krieger, David D. Ebert, Cristina Botella

“…Participants were instructed to engage in six interactive modules delivered weekly in a sequential order. The program's therapeutic content was developed following the Ryff model of well-being.The primary outcome measure used was the Connor-Davidson Resilience Scale (CD-RISC-25). …”
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Effects of Repetitive Transcranial Magnetic Stimulation Combined with Balance Acupuncture Treatment on Sleep Quality and Psychology in Patients after Stroke by YANG Huazhong, CUI Jinlong, FAN Hexin, XIONG Zhonghui, YAO Yuanmian, ZHOU Shasha, CUI Wenxiu, SUN Tianbao

“…The combined group showed better therapeutic effects than the balance acupuncture group and rTMS group alone, which is conducive to synergistic enhancement and should be recommended for promotion and application.…”
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Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic... by Partha Ray, Tomoko Hayashi, Karen Messer, Stephen Schoenberger, Aaron Miller, Dennis Carson, Sara McArdle, Zbigniew Mikulski, Jayanth S Shankara Narayanan, Suna Erdem, Herve Tiriac, Minya Pu, Rebekah R White

“…Here, we aim to generate meaningful therapeutic immune effects by combining IRE with local (intratumoral) delivery of a CD40 agonistic antibody (CD40Ab).Methods KPC46 organoids were generated from a tumor-bearing male KrasLSL-G12D-p53LSL-R172H-Pdx-1-Cre (KPC) mouse. …”
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NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder by Bin Gong, Chenxu Xiao, Yu Feng, Yu Feng, Jing Shen

“…These findings offer promising directions for precision medicine and novel therapeutic strategies in mental health treatment.…”
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Anosmia, dysgeusia and malnutrition in chronic kidney disease: A systematic review by Gaetano Ferrara, Sara Morales Palomares, Giuliano Anastasi, Mauro Parozzi, Lea Godino, Domenica Gazineo, Marco Sguanci, Stefano Mancin

“…The analysis of the interconnection between anosmia, dysgeusia, and malnutrition emerges as a crucial starting point for improving nutritional outcomes in chronic kidney disease (CKD) patients, emphasizing the need for accurate assessment and targeted therapeutic interventions to ensure better nutritional health and improved quality of life for these patients. …”
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BCL-2 overexpression exosomes promote the proliferation and migration of mesenchymal stem cells in hypoxic environment for skin injury in rats by Ying Wang, Guang Li, Guofeng Li, Yutao Pan, Zhongmin Liu

“…The wound treated with MSCs‐BCL-2 promotes the compose of new blood vessels and granulation tissue in the wound, the redifferentiation of epithelial cells and the remodeling of collagen, which has a high therapeutic prospect for chronic wounds and skin regeneration.…”
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Complex program for the prevention of the development and progression of refractive errors in school year children by T.K. Botabekova, N.A. Aldasheva, V.R. Abdullina, I.S. Stepanova, B.I. Isergepova, Zh.S. Iskakbaeva

“…Iskakbaeva²</b> </p> <p> <b>¹Kazakhstan-Russian Medical University, Almaty, Kazakhstan</b> </p> <p> <b>²Kazakhstan Research Institute of Eye Diseases, Almaty, Kazakhstan</b> </p> <p> <i><b>Aim</b>: to develop a complex preventive and therapeutic program for refractive errors in school year children.…”
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Mechanism study of KCMF1 promoting proliferation and NF-κB signaling transduction in colorectal cancer cells by WU Zhibai, XU Guiqin, ZHANG Li, YANG Zhaojuan, LIU Yun, JIAO Kun, CHEN Zehong, XU Chen, ZUO You, ZHENG Ningqian, YE Zhiqian, LIU Yongzhong

“…KCMF1 may be a potential new therapeutic target for CRC.…”
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USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer by Fang Yuan, Juan Xu, Lingmei Xuan, Chan Deng, Wei Wang, Rong Yang

“…Background: Radiotherapy is a major modality for esophageal cancer (ESCA) treatment, yet radioresistance severely hampers its therapeutic efficacy. Ubiquitin-specific peptidase 14 (USP14) is a novel deubiquitinase and can mediate cancer cells’ response to irradiation, although the underlying mechanism remains unclear, including in ESCA. …”
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Phenotypes of primary sclerosing cholangitis in children by M.B. Dyba, V.S. Berezenko

“…ASC and isolated PSC have similar phenotypes of biliary and intestinal lesions, however, they differ in terms of clinical course and therapeutic approaches. Involvement of the large bile duct alone in children with PSC is associated with rapid formation of liver fibrosis and cirrhosis. …”
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Pengaruh Hiperglikemia terhadap Gambaran Histopatologis Pulau Langerhans Mencit by Muhammad Farid, Eryati Darwin, Delmi Sulastri

“…With complex interactions of risk factors on the disease, therapeutic approach of diabetes still centered on preventive measures and diagnosis was made entirely from the presence of hyperglycemia. …”
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Effects of Jianpi therapy for cancer-related fatigue:a meta-analysis of randomized controlled trials by Jiaxing Dai, Jiaxing Dai, Huili Shui, Huili Shui, Huili Shui, Yuan Wu, Huanghui Zhang, Huanghui Zhang, Yuanyin Li, Yuanyin Li, Shaowang Zhang, Shaowang Zhang, Bing Yang, Bing Yang, Bing Yang, Dongxin Tang, Dongxin Tang, Dongxin Tang

“…PurposeThe Jianpi therapeutic strategy in traditional Chinese medicine aims to enhance the spleen’s digestive function and overall wellness. …”
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The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Given the anti-inflammatory effect of transcutaneous auricular vagus nerve stimulation (taVNS) and its ability to promote brain plasticity, taVNS has emerged as a promising therapeutic option for SAH patients. However, the effects of taVNS on cardiovascular dynamics in critically ill patients, like those with SAH, have not yet been investigated. …”
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Efficacy and safety of first-line PD-1/PD-L1 inhibitor in combination with CTLA-4 inhibitor in the treatment of patients with advanced non-small cell lung cancer: a systemic review... by Huimin Zhao, Shanshan Huang, Jianyu Wu, Yanlan Lu, Yue Zou, Haijian Zeng, Chunlan Li, Jin Wang, Xiaochen Zhang, Xiaochen Zhang, Siliang Duan, Siliang Duan, Weiming Liang

“…Specifically, CP may function as a therapeutic alternative for individuals with low or negative PD-L1 expression, resulting in enhanced long-term outcomes compared to chemotherapy or P. …”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…Here, our DKD mouse kidney single-cell RNA sequencing conveys a more comprehensive mitochondrial profile, which helps us further understand the therapeutic response of this unique organelle family to drugs. …”
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Splenic artery aneurysms – a systematic review of the literature by Marta Machado, Andreia Coelho, João Peixoto, Luís Fernandes, Roberto Boal, Francisco Basílio, Patrícia Carvalho, Beatriz Guimarães, Pedro Brandão, Alexandra Canedo

“…A detailed and individualized analysis of each case and a sufficient understanding of the anatomy and hemodynamics of a particular aneurysm should guide the therapeutic decision. OS has good results in treating SAA with lower morbidity and reintervention than ET. …”
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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

“…Endothelial specific silencing of AnxA8 reduced atherosclerosis progression. Therapeutic interventions to reduce AnxA8 expression may delay atherosclerosis progression.…”
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Alkaloids extracted from Dendrobium officinale grown in diverse environments exhibited robust antioxidative and antiaging activity by Yichen Liu, Arome Solomon Odiba, Qi Yu, Jin Xie, Nkwachukwu Oziamara Okoro, Guiyan Liao, Xinchen Zhu, Bin He, Cheng Jin, Wenxia Fang, Bin Wang

“…Due to the increase in aging populations and the prevalence of aging-associated diseases, there is a growing interest in finding therapeutic interventions. Antioxidants play a vital role in mitigating the adverse conditions associated with aging. …”
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Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

“…Targeting colonic inflammation may involve inhibiting LCA and members of the Prevotellaceae family as potential therapeutic strategies.…”
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