Biometabolic Distribution of Tc-3PRGD2 and its Potential Value in Monitoring Chemotherapeutic Effects by Jian-Guo Wu, Shao-Li Song, Xiang Zhou, Fan Wang, Yin-Yan Zhu, Lei Xie, Fan Zhang, Gang Huang

“…Due to the specific target mechanism and the cost-effective value of 99m Tc-3PRGD2, 99m Tc-3PRGD2 SPECT imaging may have potential in detecting the therapeutic effects of anticancer therapy.…”
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Morphological, Physiological, and Transcriptional Changes in <i>Crocus sativus</i> L. Under In Vitro Polyethylene Glycol-Induced Water Stress by Suman Gusain, Rohit Joshi

“…It is highly valued for its therapeutic and commercial uses. While saffron cultivation generally requires minimal water, insufficient irrigation can negatively impact its yield. …”
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Phytochemical Profile and Antioxidant Activity of Nigella sativa L Growing in Morocco by Salima Tiji, Ouijdane Benayad, Mohamed Berrabah, Ibrahim El Mounsi, Mostafa Mimouni

“…Nigella sativa L (NS) is a powerful antioxidant and medicinal plant with many therapeutic applications particularly in traditional medicine for respiratory, gastrointestinal, rheumatic, and inflammatory disorders, as well as cancer. …”
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The efficacy and safety of Baduanjin exercise as complementary therapy for pain reduction and functional improvement in knee osteoarthritis: A meta-analysis of randomized controlle... by Ye Tian, Zi-Yuan Liu, Jia-Hao Wang, Jing-Hua Qian

“…While Baduanjin exercise, a traditional Chinese exercise therapy, is part of complementary and alternative medicine, its therapeutic value for knee osteoarthritis remains uncertain due to limited supporting evidence. …”
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Molecular Characterization and Clinical Characteristics of m5C-Based RNA Methylation in Spinal Cord Injury: Validated by qPCR by Liang Cao, Wen Jun Pi, Qiang Zhang, Qing Li

“…We also hope our findings may contribute to further mechanistic and therapeutic research on the role of key m5C regulators after SCI.…”
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Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity by Els F. Halff, Sridhar Natesan, David R. Bonsall, Mattia Veronese, Anna Garcia-Hidalgo, Michelle Kokkinou, Sac-Pham Tang, Laura J. Riggall, Roger N. Gunn, Elaine E. Irvine, Dominic J. Withers, Lisa A. Wells, Oliver D. Howes

“…Following subchronic ketamine administration, elevated KiMod as compared to control condition was measured with a large effect size for both methods (intraperitoneal: Cohen’s d=1.3; intravenous: Cohen’s d=0.9), providing further evidence that ketamine has lasting effects on the dopamine system, which could contribute to its therapeutic actions and/or abuse liability.…”
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Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p. by Shengjuan Lu, Lin Zeng, Guojun Mo, Danqing Lei, Yuanhong Li, Guodi Ou, Hailian Wu, Jie Sun, Chao Rong, Sha He, Dani Zhong, Qing Ke, Qingmei Zhang, Xiaohong Tan, Hong Cen, Xiaoxun Xie, Chengcheng Liao

“…These findings provide a new prognostic marker and therapeutic target for the prognosis and treatment of DLBCL.…”
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CAR T-cell detection scoping review: an essential biomarker in critical need of standardization by Naomi Taylor, Nirali N Shah, David P Turicek, Victoria M Giordani, Josquin Moraly

“…As such, the tools used to detect CAR T-cells following infusion are fundamental for optimizing this therapeutic approach. Nevertheless, despite the critical value of this essential biomarker, there is significant variability in CAR T-cell detection methods as well as the frequency and intervals of testing. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Conclusion Prophylactic CPAP application following therapeutic balloon dilatation in pediatric patients who have developed subglottic stenosis due to acquired or congenital causes appears to effectively shorten recovery time and may have a role in decreasing postoperative pulmonary complications; however, more research is recommended to further confirm these findings. …”
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Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…The current literature is limited and lacks high-quality research Future randomized studies are needed to focus on therapeutic effects of cannabis in otolaryngology. Substantial work remains to guide clinicians to suggest safe, evidence-based choices for cannabis use. …”
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The Effectiveness of β-glucan in the Treatment of Caprine Mastitis Induced by Candida albicans by Saddam H Mahmoud, Shaimaa N Yassein

“…Its ability to lower inflammatory cytokine levels and eliminate fungal infections highlights its promise as a therapeutic option, particularly in combination with Nystatin, for managing fungal mastitis‎‎‎. …”
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The potential of aloe vera gel utilization for skin wound healing in rats based on GC–MS and HPLC chemical profile by Nadia Mohamed Said Arafa, Huda Mohammad Ahmad Hummadi, Gehan Moustafa Badr

“…Conclusion Results revealed aloe gel ethanol extract advantage over raw gel for wound healing which may be related to chemical constituents’ variation interpreted in interest to the extract as an efficient therapeutic, cost-effective, available wound healing material.…”
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ucumeropsis mannii seed oil protects against Bisphenol A- induced testicular mitochondrial damages by Patrick Maduabuchi, Aja, Hilary Akobi, Ogwoni, Peter Chinedu, Agu, Ejike Ugbala, Ekpono, Joshua Nonso, Awoke, Oliver Ugochukwu, Ukachi, Obasi Uche, Orji, Boniface Anthony, Ale, Chinonso Peter, Nweke, Esther Ugo, Alum, Darlington C., Chukwu, Christian E., Offor, Atamgba Agbor, Asuk, Ejike, Daniel Eze, Ojochenemi E., Yakubu, J. B., Akob, Onyedika Gabriel, Ani, Chinaza Godswill, Awuchi

“…Our findings suggest that C. mannii seed oil has considerable antioxidant potential which can be explored in therapeutic development against systemic toxicity induced by exposure to bisphenol A. …”
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Optimizing injection accuracy for Baxter’s nerve entrapment: an ultrasonography-guided approach based on anatomical surface landmarks by Jung-woo Choi, Hyung-Jin Lee, Yong-Seok Nam, Mi Young Shin, Sang-Hyun Kim, Jun-Ho Kim, In-Beom Kim

“…This study provides anatomical guidelines for optimal transducer placement using two specific landmarks, the most inferior tip of the medial malleolus (A) and the most protruding posterior tip of the calcaneus (B), to enhance the diagnostic and therapeutic injection efficacy for proximal and distal entrapment sites.Materials and Methods Eighty-six feet from 45 fresh cadavers (25 male and 20 female) were dissected to determine Baxter’s nerve (BN) localization. …”
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Association of preoperative ultrasonographic parameters of the contralateral kidney with long-term serum creatinine in cats treated for unilateral ureteral obstruction by Diego Pulido Vega, Jérémie Ficheroulle, Jérémie Ficheroulle, Mathieu Manassero, Jeremy Mortier, Christelle Maurey

“…IntroductionPrediction of renal recovery after surgical management of feline unilateral ureteral obstruction (UO) is crucial to guide therapeutic decisions, but predictors of this outcome are still lacking. …”
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Quantitative Physiologic MRI Combined with Feature Engineering for Developing Machine Learning-Based Prediction Models to Distinguish Glioblastomas from Single Brain Metastases by Seyyed Ali Hosseini, Stijn Servaes, Brandon Hall, Sourav Bhaduri, Archith Rajan, Pedro Rosa-Neto, Steven Brem, Laurie A. Loevner, Suyash Mohan, Sanjeev Chawla

“…<b>Background</b>: The accurate and early distinction of glioblastomas (GBMs) from single brain metastases (BMs) provides a window of opportunity for reframing treatment strategies enabling optimal and timely therapeutic interventions. We sought to leverage physiologically sensitive parameters derived from diffusion tensor imaging (DTI) and dynamic susceptibility contrast (DSC)–perfusion-weighted imaging (PWI) along with machine learning-based methods to distinguish GBMs from single BMs. …”
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Integrating machine learning with mendelian randomization for unveiling causal gene networks in glioblastoma multiforme by Lixin Du, Pan Wang, Xiaoting Qiu, Zhigang Li, Jianlan Ma, Pengfei Chen

“…Despite advances in understanding its molecular mechanisms, effective therapeutic strategies remain elusive due to the tumor’s genetic complexity and heterogeneity. …”
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Transcriptome analysis of ovarian cancer uncovers association between tumor-related inflammation/immunity and patient outcome by Jingfang Wang, Wenrui Zhu, Xia Li, Yuanyuan Wu, Wenhui Ma, Yangzhou Wang, Weihong Zhao, Fang Wei, Wenhao Wang

“…Although more and more drugs have been approved, the therapeutic effect of PARPi is still very limited. With the rapid development of PD-1/PD-L1, CTLA-4, oncolytic viruses, cancer vaccines, adoptive cell therapy, etc., tumor immunotherapy has provided new opportunities for the treatment of ovarian cancer.MethodsThis study used comprehensive transcriptome analysis across multiple databases to gather gene transcripts and clinical features of normal ovarian samples and tissue samples from ovarian cancer. …”
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Efficacy of rituximab as second-line therapy for autoimmune encephalitis: A systematic review and meta-analysis by Lin-ming Zhang, Xuan-lin Xing, Bing-ran Zhang, Qiu-juan Zhang, Yan-lin Zhu, Shu-ji Gao, Ming-wei Liu

“…This study systematically evaluated and meta-analyzed the efficacy of rituximab in AE patients who either failed or exhibited inadequate responses to first-line treatments, aiming to refine and optimize therapeutic strategies for AE. Methods: A comprehensive search of PubMed, Embase, and the Cochrane Library databases was conducted, covering studies published up to June 10, 2024. …”
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Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

“…M. smithii seems to interact with the bacterial ecosystem affecting butyrate, histidine, phenylalanine, and linoleic acid metabolism with a positive impact on cognition, constituting a promising therapeutic target to enhance cognitive performance, especially in subjects with obesity.…”
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