Meta-Analysis of the Therapeutic Effects of Stem Cell-Derived Extracellular Vesicles in Rodent Models of Hemorrhagic Stroke by Conglin Wang, Bo Yan, Pan Liao, Fanglian Chen, Ping Lei

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Whole slide image based deep learning refines prognosis and therapeutic response evaluation in lung adenocarcinoma by Tao Chen, Jialiang Wen, Xinchen Shen, Jiaqi Shen, Jiajun Deng, Mengmeng Zhao, Long Xu, Chunyan Wu, Bentong Yu, Minglei Yang, Minjie Ma, Junqi Wu, Yunlang She, Yifan Zhong, Likun Hou, Yanrui Jin, Chang Chen

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Exploring the therapeutic potential of tDCS, TMS and DBS in overcoming tobacco use disorder: an umbrella review by Graziella Orrù, Marina Baroni, Ciro Conversano, Angelo Gemignani

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Evaluating the therapeutic communication skills of nursing students in the clinical setting: The experiences of students, patients and patients’ relatives by Neşe Mercan, Sevinç Mersin

Subjects: “…Therapeutic communication…”
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The Implementation of Therapeutic Alliance in the Rehabilitation of an Elite Pediatric Athlete with Salter-Harris Fracture: A Case Report by Lucas VanEtten, Matthew Briggs, John DeWitt, Cody Mansfield, Christopher Kaeding

“…# Background/Purpose Although research on the value of therapeutic alliance is prominent in other areas of health care, physical therapy research is limited. …”
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Formulation of Snack Bar Based on White Mussel as TFA (Therapeutic Food for Anemia) To Improve Adolescents Nutrition by Arie Dwi Alristina, Rizky Dzariyani Laili, Luki Mundiastuti, Dewinta Hayudanti, Rossa Kurnia Ethasari

“…In order to break the chain of stunting, giving TFA (Therapeutic Food for Anemia) to adolescent females at school is one of the measures taken. …”
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The Domestic Cat as a Large Animal Model for Characterization of Disease and Therapeutic Intervention in Hereditary Retinal Blindness by Kristina Narfström, Koren Holland Deckman, Marilyn Menotti-Raymond

“…The large mammal models may be used for thorough clinical characterization of disease processes, understanding the effects of specific mutations, elucidation of disease mechanisms, and for development of therapeutic intervention. Two well-characterized feline models are addressed in this paper. …”
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Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice by Ryan Brown, Donna M. Small, Declan F. Doherty, Leslie Holsinger, Robert Booth, Richard Williams, Rebecca J. Ingram, J. Stuart Elborn, Marcus A. Mall, Clifford C. Taggart, Sinéad Weldon

“…In this study, we build upon this work to examine the effects of therapeutic intervention with a CatS inhibitor in adult βENaC-Tg mice with established disease. …”
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Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…Additionally, this review explores the potential of Clec9a-targeted approaches to enhance the immunogenicity of tumor vaccines and addresses the utilization of Clec9a as a delivery target for specific agonists (such as STING agonists and αGC) to enhance their therapeutic effects. This novel approach leverages Clec9a’s capacity to improve the precision and efficacy of these immunomodulatory molecules in tumor treatment. …”
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Retinal Lineage Therapeutic Specific Effect of Human Orbital and Abdominal Adipose-Derived Mesenchymal Stem Cells by Bryan Krief, Shira Weisthal Algor, Itay Nakdimon, Ayala Elhikis, Moshe Benhamou, Anouk Savir Kadmon, Shay Keren, Oded Ohana, Ilan Feldman, Ran Ben Cnaan, Igal Leibovitch, Anat Loewenstein, Adiel Barak, Aya Barzelay

“…Taken together, we demonstrated a lineage-specific therapeutic effect for either OASCs or ABASCs in retinal regeneration.…”
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Resveratrol, Piceatannol, Curcumin, and Quercetin as Therapeutic Targets in Gastric Cancer—Mechanisms and Clinical Implications for Natural Products by Paulina Warias, Paulina Plewa, Agata Poniewierska-Baran

“…Gastric cancer remains a significant global health challenge, driving the need for innovative therapeutic approaches. Natural polyphenolic compounds such as resveratrol, piceatannol, curcumin, and quercetin currently show promising results in the prevention and treatment of various cancers, due to their diverse biological activities. …”
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Prognostic signature and therapeutic drug identification for dilated cardiomyopathy based on necroptosis via bioinformatics and experimental validation by Han Yang, Zhenwei Wang, Yawei Xu, Yimei Du, Haibo Yang, Yang Lu

“…These findings underscore the clinical relevance of necroptosis-related genes in assessing DCM progression and prognosis and highlight their potential for targeted therapeutic development.…”
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A potential therapeutic approach for ulcerative colitis: targeted regulation of mitochondrial dynamics and mitophagy through phytochemicals by Jianping Zhou, Yuting Xi, Ting Wu, Xiaoyu Zeng, Jun Yuan, Lei Peng, Hao Fu, Ce Zhou

“…In this review, we discuss the key effects of mitochondrial dynamics and mitophagy on the pathogenesis of UC, with a particular focus on the cellular energy metabolism, oxidative stress, apoptosis, and immunoinflammatory activities. The therapeutic efficacy of existing drugs and phytochemicals targeting the mitochondrial pathway are discussed to reveal important insights for developing therapeutic strategies for treating UC. …”
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Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy by Kazunori Sango, Hideji Yako, Hideji Yako, Naoko Niimi, Shizuka Takaku

“…Herein, recent studies with these cell lines regarding the pathogenic factors of DPN (augmentation of the polyol and other collateral glycolysis pathways, glycative and oxidative stress-induced cell injury, autophagic and proteostatic disturbances, etc.) and therapeutic strategies targeting these factors are introduced.…”
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The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE−/− Mice by Weiling Leng, Xinshou Ouyang, Xiaotian Lei, Mingxia Wu, Liu Chen, Qinan Wu, Wuquan Deng, Ziwen Liang

“…Dapagliflozin may be of therapeutic potential for diabetic atherosclerosis induced by high-fat diet, and these benefits may depend on the inhibitory effect on the secretion of IL-1β by macrophages via the ROS-NLRP3-caspase-1 pathway.…”
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Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study by Myungsung Kim, Seonmi Lee, Sieun Kim, Jeong-in Heo, Sangil Lee, Yu-Bin Shin, Chul-Hyun Cho, Dooyoung Jung

“…User insights emphasize the importance of empathy, accessibility, and structured conversations in achieving therapeutic goals. Trial RegistrationClinical Research Information Service (CRIS) KCT0009288; https://tinyurl.com/hxrznt3t…”
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Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis by Yuqi Wang, Yuqi Wang, Jun Ma, Haoyu Wang, Haoyu Wang, Jingzheng Yi, Yuxin Bai, Yuxin Bai, Min Hu, Min Hu, Jiaqing Yan, Jiaqing Yan

“…This study establishes that mesalazine can treat periodontitis through modulation of the periodontal flora and its anti-inflammatory properties, thus broadening its classical therapeutic applications.…”
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Therapeutic effects of traditional Chinese medicine on Hepatitis B-related liver fibrosis: A case study by Quanbin Wu

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Combined Treatment With Leuprolide Acetate and Burosumab in X-linked Hypophosphatemia and Precocious Puberty: A Therapeutic Response by Gustavo Tempone Cardoso Penna, MS, Carolina Costa Figueiredo, MD, MSc, Nara Michelle de Araújo Evangelista, MD, MSc, Vânia de Fátima Tonetto Fernandes, MD, PhD, Patricia Salmona, MD, Guido de Paula Colares Neto, MD, PhD

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Circular RNAs in cancer: roles, mechanisms, and therapeutic potential across colorectal, gastric, liver, and lung carcinomas by Ayushi Malviya, Rajabrata Bhuyan

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