Therapeutic Potential of Agmatine in Essential Tremor Through Regulation of Lingo‐1 and Inflammatory Pathways by Zeynab Pirmoradi, Zahra Esmaili, Mohsen Nakhaie, Kristi A. Kohlmeier, Mohammad Shabani, Moazamehosadat Razavinasab, Mehran Ilaghi

“…These results suggest promise for agmatine as a prospective therapeutic agent in ET.…”
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Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview by Katia D’Ambrosio, Anna Di Fiore, Emma Langella

“…In this mini-review, we aim to present an overview of the most significant structural results related to the development of novel therapeutics employing hCA inhibitors as dual-targeting compounds for the treatment of complex diseases.…”
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Therapeutic Drug Monitoring of Vancomycin in Hemodialysis Patients in a Hospital in North-East Romania by Aurelia Crețu, Luanda Irina Mititiuc, Iulia-Daniela Lungu, Mihaela Mihaila, Irina Dima, Adrian Covic, Cristina Mihaela Ghiciuc

“…<b>Conclusions</b>: a therapeutic level of vancomycin can often be difficult to achieve because of different reasons, mainly in hemodialysis patients.…”
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DIFFERENCES IN PATIENT SATISFACTION REGARDING NURSES’ THERAPEUTIC COMMUNICATION IN CLASS I, II, AND III IN PATIENT ROOMS AT RSUD SUBANG by Maya Rahma Aulia, Nuridha Fauziyah, Novian Mahayu Adiutama

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Penerapan Komunikasi Terapeutik Pada Pasien Skizofrenia Dalam Mengontrol Halusinasi Di RS Jiwa Menur Surabaya by Yosi Apriliani, Esti Widiani

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Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer by Jeremy L. Pinyon, Georg vonJonquieres, Stephen L. Mow, Amr Al Abed, Keng‐Yin Lai, Mathumathi Manoharan, Edward N. Crawford, Stanley H. Xue, Sarah Smith‐Moore, Lisa J. Caproni, Sarah Milsom, Matthias Klugmann, Nigel H. Lovell, Gary D. Housley

“…The findings support adoption of SCD‐CC‐GET for vaccines and immunotherapies, and extend the utility of this technology to meet the demand for efficient vector‐free, precision, deep tissue delivery of NA therapeutics.…”
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Clinical and analytical monitoring of patients with multiple sclerosis on anti-CD20 therapeutics: a real-world safety profile study by André Aires Fernandes, André Aires Fernandes, Ana Lídia Neves, Ana Lídia Neves, Daniela Ferro, Daniela Ferro, Mafalda Seabra, Mafalda Seabra, Teresa Mendonça, Ricardo Soares dos Reis, Ricardo Soares dos Reis, Maria José Sá, Joana Guimarães, Joana Guimarães, Pedro Abreu, Pedro Abreu

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Virtual screening and molecular dynamics simulations identify repurposed drugs as potent inhibitors of Histone deacetylase 1: Implication in cancer therapeutics. by Mohammed Alrouji, Sabina Yasmin, Mohammed S Alshammari, Fahad A Alhumaydhi, Sharaf E Sharaf, Moyad Shahwan, Anas Shamsi

“…The findings suggest that Alectinib holds promise as a therapeutic lead for HDAC1-associated carcinogenesis after required validation.…”
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Brain-Derived Neurotrophic Factor and Nerve Growth Factor Therapeutics for Brain Injury: The Current Translational Challenges in Preclinical and Clinical Research by Serena-Kaye Sims, Brynna Wilken-Resman, Crystal J. Smith, Ashley Mitchell, Lilly McGonegal, Catrina Sims-Robinson

“…Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) serve as potential therapeutic options to increase neural repair and recovery as they promote neuroprotection and regeneration. …”
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The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class? by Ricardo Godinho, Cristina Mega, Edite Teixeira-de-Lemos, Eugénia Carvalho, Frederico Teixeira, Rosa Fernandes, Flávio Reis

“…Incretin-based therapies, the most recent therapeutic options for type 2 diabetes mellitus (T2DM) management, can modify various elements of the disease, including hypersecretion of glucagon, abnormal gastric emptying, postprandial hyperglycaemia, and, possibly, pancreatic β cell dysfunction. …”
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Copper Imparts a New Therapeutic Property to Resveratrol by Generating ROS to Deactivate Cell-Free Chromatin by Salooni Khanvilkar, Indraneel Mittra

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Recent advances in the prevention of secondary ischemic stroke: A narrative review by Yue Qiao, Aminah I. Fayyaz, Yuchuan Ding, Xunming Ji, Wenbo Zhao

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Understanding stakeholder views of the use of digital therapeutic interventions within children and young people’s mental health services by Brioney Gee, Brioney Gee, Tim Clarke, Tim Clarke, Jess Garner, Bonnie Teague, Bonnie Teague, Georgianna Coote, Aoife Dunne, Rachel McGuire, Andrew Laphan, Manjul Rathee, Jon Wilson, Jon Wilson

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Targeting quorum sensing for manipulation of commensal microbiota by Zachary Ziegert, Matthew Dietz, Max Hill, Marjais McBride, Elizabeth Painter, Mikael H. Elias, Christopher Staley

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Multispanning membrane protein SIDT2 increases knockdown activity of gapmer antisense oligonucleotides by Kohshi Kusumoto, Kiyomi Sasaki, Yasunori Uchida, Ayaka Utsumi, Tokuyuki Yoshida, Satoshi Obika, Takao Inoue, Keiichiro Okuhira

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Diagnosis and management of rheumatic manifestations of Hepatitis B, Hepatitis C and immunodeficiency Virus by Arun Ramesh Chogle

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An aggregation-induced emission-active lysosome hijacker: Sabotaging lysosomes to boost photodynamic therapy efficacy and conquer tumor therapeutic resistance by Hang Zou, Pingping Wang, Zhihao Bai, Liping Liu, Jingtong Wang, Yanfang Cheng, Bairong He, Zujin Zhao, Lei Zheng

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Transfusion efficacy and influencing factors of patients transfused with different therapeutic doses of platelets: a comparative analysis by ZHU Jianling, CHENG Tingting, MA Chunya, FU Lihui, SHI Hongmei, YU Yang

Subjects: “…0.5 therapeutic dose…”
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Retraction: Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases. by PLOS ONE Editors

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cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

“…It explores interactions between DNA damage response pathways and immune modulation, highlighting the impact of cGAS/STING activation or suppression in ovarian, cervical, and endometrial cancers. The therapeutic potential of STING agonists, PARP inhibitors, and targeted immunotherapies is reviewed, demonstrating how these approaches can boost immune responses, counteract chemotherapy resistance, and improve patient outcomes. …”
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