Biologically synthesized iron oxide nanoparticles as a therapeutic agent for cancer diagnosis and treatment by Geetha Anbalagan, Jeeva Jothi Kumaravel, Balachandran Subramanian

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Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects by Boyun Gou, Guoqing Chen, Shicong Huang, Na Ning, Qian Gu, Shuai Duan, Yuhua Du, Yi Nan, Ling Yuan

“…This article reviews the anticancer effects of a fruit, food, and drug, jujube, which have been shown in current studies, and analyzes its therapeutic mechanism, active ingredients, extraction and isolation methods, as well as its synergistic and attenuation performance in cancer. …”
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Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis by Damien Veret, Gautier Tejedor, Esther Perez, Alison Chomette, Maylis Farno, Rosanna Ferreira-Lopez, Louis Dagneaux, Yves-Marie Pers, Christian Jorgsensen, Claire Gondeau, Jean-Marc Brondello

“…One factor contributing to this therapeutic barrier could be the presence of senescent cells in OA joints. …”
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Targeting immune cellular populations and transcription factors: unraveling the therapeutic potential of JQF for NAFLD by Lijuan Zhou, Jingyi Zhao, Kaile Ma, Rui Hao, Chensi Yao, Xiaowen Gou, Chuanxi Tian, Li Wan, Min Li, Xiaolin Tong

“…Advanced subcluster and cell communication analyses identified key macrophage (KCs, MoMFs) and T cell (Tc, Th2) subpopulations in JQF’s therapeutic actions. Further SCENIC analysis additionally uncovered the essential transcription factors that regulate these cell subclusters, such as Stat2, Mta3, Eomes, and Etv5.ConclusionOverall, our research suggests a promising potential therapeutic agent and identifies critical cell populations and transcription factors that contribute to its therapeutic effects, thereby revealing potential therapeutic targets for NAFLD.…”
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Cuproptosis related lncRNA signature as a prognostic and therapeutic biomarker in osteosarcoma immunity by Ziwei Gao, Siqi Chen, Wei Ye

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Microbiome interplays in the gut-liver axis: implications for liver cancer pathogenesis and therapeutic insights by Xuran Wang, Bin Zhang, Runqiu Jiang

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Therapeutic Adherence of Patients with Type 2 Diabetes Mellitus in Four Health Areas of the Country by Addys María Díaz Piñera, Armando Rodríguez Salvá, Fernando Jesús Achiong Estupiñán, Dania Lidia Cardona Garbey, Geominia Maldonado Cantillo, Esteban Augusto Londoño Agudelo, Patrick Van der Stuyft

“…<br /><strong>Objective:</strong> to characterize therapeutic adherence in type 2 diabetic patients belonging to four health areas, from two municipalities in Cuba. …”
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LncRNA HOXA10-AS as a novel biomarker and therapeutic target in human cancers by Xin Hu, Yong Wang, Sijia Zhang, Xiaosi Gu, Xiaoyu Zhang, Lianlian Li, Lianlian Li

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Maternal-related factors associated with development and improvement of peripartum cardiomyopathy and therapeutic outcomes of bromocriptine by I Gusti Bagus Mulia Agung Pradnyaandara, Ryan Saktika Mulyana, Jane Carissa Sutedja, Gusti Ngurah Prana Jagannatha, I Bagus Satriya Wibawa, Fanny Deantri, I Wayan Agus Surya Pradnyana, Bryan Gervais de Liyis

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Investigating the Therapeutic Mechanisms of Total Saikosaponins in Alzheimer’s Disease: A Metabolomic and Proteomic Approach by Huiling Wei, Tianyi Du, Weiwei Zhang, Wei Ma, Yao Yao, Juan Li

“…Total saikosaponins (TSS), the primary bioactive components in <i>Bupleurum chinense</i>, have shown promising therapeutic effects against AD in previous studies. …”
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An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024) by Aly M. Waseem, Ranya Mohammed Elmagzoub, Mervat Mohammed Mazhar Abdelgadir, Areej Al Bahir, N.S. Abd EL-Gawaad, Ahmed S. Abdel-Samea, Devendra Pratap Rao, Konstantinos Kossenas, Stefan Bräse, Hamada Hashem

“…Quinoxaline derivatives have garnered significant attention due to their wide-ranging therapeutic applications. Research from 2020 to 2024 has demonstrated their potent bioactivity across various domains, including anticancer, antimicrobial, antiviral, anti-inflammatory, and antidiabetic activities. …”
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Therapeutic potential of bisphosphonates - review of medical indications, mechanism of action, interactions and adverse effects by Agnieszka Mikosińska, Mateusz Litwin, Jakub Parys, Patrycja Kałuziak, Aleksandra Witek, Martyna Kaźmierczak, Stanisław Jesionek, Marta Jajczak, Maciej Mossakowski

“…This study focuses on their therapeutic potential and associated risks, highlighting the need for further research in this area. …”
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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer by Jilong Hu, Zhinan Zheng, Jia Lei, Yuxin Cao, Qiyun Li, Zhi Zheng, Chuanjun Chen

“…We believe that targeting the EZH2-PPAR axis is a potential therapeutic pathway for PC.…”
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Therapeutic effects of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content by Danielle J. Beetler, Danielle J. Beetler, Danielle J. Beetler, Presley Giresi, Damian N. Di Florio, Damian N. Di Florio, Damian N. Di Florio, Jessica J. Fliess, Elizabeth J. McCabe, Molly M. Watkins, Molly M. Watkins, Molly M. Watkins, Vivian Xu, Matthew E. Auda, Katelyn A. Bruno, Katelyn A. Bruno, Emily R. Whelan, Emily R. Whelan, Emily R. Whelan, Stephen P. C. Kocsis, Brandy H. Edenfield, Sierra A. Walker, Sierra A. Walker, Sierra A. Walker, Logan P. Macomb, Kevin C. Keegan, Angita Jain, Angita Jain, Angita Jain, Andrea C. Morales-Lara, Isha Chekuri, Anneliese R. Hill, Houssam Farres, Joy Wolfram, Joy Wolfram, Atta Behfar, Atta Behfar, Paul G. Stalboerger, Andre Terzic, Andre Terzic, Leslie T. Cooper, DeLisa Fairweather, DeLisa Fairweather, DeLisa Fairweather

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Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective by Stefano Sanduzzi Zamparelli, Alessandro Sanduzzi Zamparelli, Marialuisa Bocchino

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Therapeutic Benefit of Vernonia amygdalina in the Treatment of Diabetes and Its Associated Complications in Preclinical Studies by Du-Bois Asante, Gideon Akuamoah Wiafe

“…In this review, we discuss the therapeutic potential of VA in diabetes and its associated complications. …”
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The Therapeutic Effect of Adipose-Derived Mesenchymal Stem Cells for Radiation-Induced Bladder Injury by Xuefeng Qiu, Shiwei Zhang, Xiaozhi Zhao, Kai Fu, Hongqian Guo

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Nattokinase as a functional food ingredient: therapeutic applications and mechanisms in age-related diseases by Hao Wu, Qian Zhang, Hao Suo, Feng Xu, Wanxu Huang, Dan Ohtan Wang

“…NK has shown excellent anti-thrombus, thrombolytic, and anti-inflammation activities that potentially delay aging and provide therapeutic effects on aging-related diseases. In this review, we critically overview the experimental and clinical evidence in the past 20 years that support the beneficial function of NK in the prevention and treatment of aging-related diseases, including cardiovascular diseases, Alzheimer’s disease, other abnormalities and cancer. …”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

“…Background: To identify optimal therapeutic strategies for managing fungating, large or ulcerating breast tumors and highlight existing gaps in the literature. …”
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Key considerations in setting up a therapeutic plasma exchange service for neurology patients  by Nicole Japzon, Aneliya Takova, Viva Levee, Ruth Han, Jenny McDonald, Benjamin Sacks, Sinead Rosser, Katharine Hunt, Laura Zambreanu, Michael Lunn, Jennifer Spillane

“…Therapeutic plasma exchange (TPE) is effective in the treatment of both neurological and non-neurological diseases. …”
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