LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation by Litao Liang, Wenbo Jia, Jinyi Wang, Yanzhi Feng, Deming Zhu, Wenhu Zhao, Chao Xu, Xiangyu Ling, Qingpeng Lv, Xiaoming Ai, Lianbao Kong, Wenzhou Ding

“…Targeting LRP11 or disrupting its interactions with USP5 or RACK1 could offer new avenues for treatment, though additional research is required to validate these therapeutic possibilities.…”
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SLC1A4 Promotes Malignant Transformation of Hepatocellular Carcinoma by Activating the AKT Signaling by Jiaoyun Zheng, Jian Gong

“…The findings in this study suggested that SLC1A4 may be a diagnostic indicator for the early HCC and a therapeutic target for the advanced HCC.…”
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Clinical application of hempseed or flaxseed oil-based lyotropic liquid crystals: Evaluation of their impact on skin barrier function by Vitek Mercedes, Matjaž Mirjam Gosenca

“…AD significantly affects patients’ quality of life, thus, there is a growing interest in the development of novel delivery systems that would improve therapeutic outcomes. Herein, eight novel lyotropic liquid crystals (LCCs) were investigated for the first time in a double-blind, interventional, before-after, single-group trial with healthy adult subjects and a twice-daily application regimen. …”
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Comparison of Clinical and Radiographic Success between MTA and Biodentine in Pulpotomy of Primary Mandibular Second Molars with Irreversible Pulpitis: A Randomized Double-Blind Cl... by Alireza Eshghi, Maryam Hajiahmadi, Mohammad Hossein Nikbakht, Mona Esmaeili

“…Introduction. Among the new therapeutic materials, MTA and Biodentine are recommended for pulpotomy and sealing the pulp. …”
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Perbedan Terapi Madu dan Multi Vitamin Terhadap Kadar Hemoglobin, Albumin dan Status Nutrisi Pada Anak Balita by Meri Neherta

“…The conclusion of this research indicates that the therapeutic effect of multivitamins is better than honey therapy combined with vitamin B complex on hemoglobin levels, albumin levels, and nutritional status (w/U) in toddlers in the work areas of Nanggalo Health Center, Padang, in 2011. …”
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SPOP Inhibition of Endometrial Carcinoma and Its Clinicopathological Relationship by Qing Zhu, Guanghui Zhang, Mingyang Tang, Rumin Zheng, Huaiyong Gan

“…This research may play a crucial role in the initiation and progression of EC, ultimately leading to fresh therapeutic targets. Explore the expression of SPOP in EC; observe its effect on the proliferation, invasion, and migration of EC cells after upregulating the expression of SPOP through RNA activation. …”
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Cryosurgery, Intralesional Methotrexate and Imiquimod for Keratoacanthoma: Tuning the Combination by Georgios Gaitanis, Ioannis D. Bassukas

“…KA stopped growing promptly with sustained clearance after 6–24 months follow up, implicating a huge potential of therapeutic synergy of the employed modalities in the management of KA. …”
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Psychotherapeutic Methods of Coping with Stress in Everyday Life by Senol TURAN, Cana AKSOY POYRAZ

“…It is helpful to determine first whether stress source can be changed, several therapeutic approaches may then be used. Lazarus and Folkman have identified two major approaches for coping with stress so-called "problem-focused" and "emotion-focused". …”
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SAMHD1 shapes deoxynucleotide triphosphate homeostasis by interconnecting the depletion and biosynthesis of different dNTPs by Claudia McCown, Corey H. Yu, Dmitri N. Ivanov

“…The regulatory relationship between the biosynthesis and depletion of different dNTPs sheds light on the emerging role of SAMHD1 in the biology of dNTP homeostasis with implications for HIV/AIDS, innate antiviral immunity, T cell disorders, telomere maintenance and therapeutic efficacy of nucleoside analogs.…”
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Navigating the depths: A comprehensive narrative review on depression in people with epilepsy by Norah A. Alkhaldi

“…In addition to pharmacology, non-pharmacological interventions are emerging as vital alternatives, enriching the therapeutic landscape. However, despite these promising avenues, a significant gap in our understanding persists, characterized by a lack of comprehensive, prospective research. …”
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Engaging and supporting young adults in smoking cessation: Insights from a mobile-based cessation program in China by Xue Weng, Hongcui Yang, Chuyu Song, Jiayu Tu, Kefeng Liu, Man Ping Wang

“…This approach included financial incentives as a motivator for quitting, sustaining cessation efforts with online group support, and building a therapeutic alliance with cessation counselors. Conclusion Mobile-based interventions, combined with peer support, financial incentives, and campus-wide smoke-free activities, can effectively engage young adults in smoking cessation. …”
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Anti-inflammatory effects of photobiomodulation in the management of osteoarthritis of the temporomandibular joint: A systematic review of animal studies by Virginia Bautista, Sandeep Talluri, Olga A Korczeniewska, Dimitrios Michelogiannakis, Junad Khan

“…Conclusions: Within the limits of the present systematic review, it is concluded that PB is a potent therapeutic agent in the management of OA in TMJ.…”
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Identification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics. by Jaime Moreno, Lise Lotte Gluud, Elisabeth D Galsgaard, Henning Hvid, Gianluca Mazzoni, Vivek Das

“…The combination of single-cell resolution from scRNAseq data, combined with tissue slide investigations and visualization of cell-cell interactions obtained through ST, paves the way for the identification of future potential therapeutic targets and developing effective therapies.…”
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Validation of Simultaneous Quantitative Method of HIV Protease Inhibitors Atazanavir, Darunavir and Ritonavir in Human Plasma by UPLC-MS/MS by Tulsidas Mishra, Pranav S. Shrivastav

“…The validated method can be useful in determining plasma concentration of these protease inhibitors for therapeutic drug monitoring and in high throughput clinical studies.…”
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Sex hormones and allergies: exploring the gender differences in immune responses by Jesús Alberto Gutiérrez-Brito, José Álvaro Lomelí-Nieto, José Francisco Muñoz-Valle, Edith Oregon-Romero, Jazz Alan Corona-Angeles, Jorge Hernández-Bello

“…We discuss the general properties of these hormones, their effects on allergic processes, and clinical observations and therapeutic results. Finally, we describe hypersensitivity reactions to these hormones.…”
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Transmembrane Amino Acid Transporters in Shaping the Metabolic Profile of Breast Cancer Cell Lines: The Focus on Molecular Biological Subtype by Elena I. Dyachenko, Lyudmila V. Bel’skaya

“…Using the cell lines presented in this review, we can trace the characteristic features inherent in each of the molecular biological subtypes of breast cancer and develop the most optimal therapeutic targets.…”
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Comparison of the Effectiveness of Interventions to Reduce Smoking in Ecuadorian Patients with Cardiovascular Diseases by Elsy Labrada González, Angélica Victoria Martínez Herrera, Manuel Conrado Ezcurdia Bárzaga

“…There are numerous therapeutic proposals from different health disciplines with the aim of facilitating the transition from habitual consumption to quitting tobacco. …”
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From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care by Masaru Tanaka

“…It focuses on key innovations such as dynamic systems modeling and network-based approaches that use genetic, molecular, and environmental data to identify new therapeutic targets. Furthermore, it emphasizes the importance of interdisciplinary collaboration and human-specific models in overcoming the limitations of traditional approaches. …”
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Pandemic mitigation: Bringing it home by Tom Reichert

“…Essential personnel are the first scheduled to receive preventive and therapeutic pharmaceuticals, followed by high risk groups, the largest of which are the elderly. …”
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Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia by Mihoko Kawai, Ryosuke Aratake, Tadashi Ogawa

“…Hence, clinicians should be knowledgeable about the risk of decreased drug levels and the need for therapeutic monitoring and dosage adjustments during pregnancy to maintain treatment efficacy and maternal and fetal health.…”
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