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7721
Viral mimicry evasion: a new role for oncogenic KRAS mutations
Published 2025-02-01“…This response has been shown to have strong cancer therapeutic potential, including by enhancing the effectiveness of immune checkpoint inhibition (ICI) therapies, and may represent a tumor suppression mechanism that needs to be overcome for malignant transformation to proceed. …”
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7722
Inflammation Modulating Activity of the Hydroethanol Stem Bark Extract of Bombax costatum in Murine Models
Published 2022-01-01“…Finally, the ability of the extract to inhibit chronic inflammation was studied using a rat adjuvant-induced arthritis model. Pre-emptive and therapeutic administration of the extract at all doses significantly suppressed the formation of oedema following prostaglandin E2 administration. …”
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7723
In Vivo Bioluminescence Imaging of Transplanted Mesenchymal Stem Cells as a Potential Source for Pancreatic Regeneration
Published 2014-10-01“…Stem cell therapy has been studied intensively as a promising therapeutic strategy toward a cure for diabetes. To study the effect of mesenchymal stem cell (MSC) transplantation for pancreatic regeneration, we monitored the localization and distribution of transplanted MSCs by bioluminescence imaging in a mouse model. …”
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7724
Neurological ct Scan Value for Ictus in Cienfuegos Province
Published 2007-05-01“…These aspects permit the reliable introduction of new therapeutic modalities in our province.<strong><br /></strong>…”
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7725
Multiple Factors Determine the Oncolytic or Carcinogenic Effects of TLRs Activation in Cancer
Published 2024-01-01“…In this review, the potential therapeutic value of TLRs in immunotherapy and its role in oncogenesis are explored. …”
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7726
Combination of AAV-CCL19 and GPC3 CAR-T Cells in the Treatment of Hepatocellular Carcinoma
Published 2021-01-01“…Chimeric antigen receptor-modified T cell (CAR-T) therapy has great potential for treating malignant tumors, especially hematological malignancies. However, the therapeutic effect of solid tumors is limited. One of the most important factors is the homing of CAR-T cells to tumor tissues in vivo. …”
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7727
Measurement of Apelin as a Biomarker and Its Relationship to Cystatin C, Copeptin, and Glomerular Filtration Rate in Serum of Patients with Acute Kidney Injury in Mosul City, Iraq
Published 2024-10-01“…Conclusion: The results showed that serum apelin levels decreased in the blood serum of the acute kidney injury group, corresponding to an increase in the level of both cystatin C and copeptin levels and a decrease in the estimated glomerular filtration rate compared to the control group, which indicates the possibility that apelin is a strong predictive biomarker for acute kidney injury, and it can play a good preventive and therapeutic role in the future.…”
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7728
School Gardens in Poland – Rediscovered Places
Published 2023-08-01“…Gradually, the view of school gardens has been changing and their therapeutic potential (hortitherapy) is noticed. [1] According to R. …”
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7729
Overview of 5-ASA in Therapy of Inflammatory Bowel Disease
Published 1994-01-01“…In patients intolerant of sulfasalazine, switching to a 5-ASA preparation usually results in tolerance and therapeutic benefit, with an occasional allergic reaction to the 5-ASA molecule limiting its use.…”
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7730
PEUSIJUEK INDIGENOUS PSYCHOTHERAPY: Being Oneness to Nature in God’s Acceptance
Published 2024-12-01“…Quasi-experiments</span> is the main method used to measure the work of peusijeuk as an alternative therapy, while in-depth interview <span class="selectable-text1">procedure also employed for unearthing therapeutical competences of peusijeut and its philosophical justification. …”
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7731
Mechanisms of Rhodopsin-Related Inherited Retinal Degeneration and Pharmacological Treatment Strategies
Published 2025-01-01“…Advancing our understanding of the interactions between photoreceptor cell death mechanisms and the specific genetic mutations driving RP is critical to accelerate the discovery and development of therapeutic strategies for this currently incurable disease.…”
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7732
Rationale for the Use of Cord Blood in Hypoxic-Ischaemic Encephalopathy
Published 2022-01-01“…Hypoxic-ischaemic encephalopathy (HIE) is a severe complication of asphyxia at birth. Therapeutic hypothermia, the standard method for HIE prevention, is effective in only 50% of the cases. …”
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7733
Comparative Analysis of the Efficiency of Medicinal Plants for the Treatment and Prevention of COVID-19
Published 2022-01-01“…According to the results of the comparative analysis, Chamaenerion angustifolium Seg. showed itself as the most prospective medicinal plant with the greatest pharmacological effect compared with other types of medicinal plants. Its therapeutic properties allow physiological relief of 18 symptoms of coronavirus infection. …”
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7734
Neuromuscular Plasticity: Disentangling Stable and Variable Motor Maps in the Human Sensorimotor Cortex
Published 2016-01-01“…Motor maps acquired with transcranial magnetic stimulation (TMS) are evolving as a biomarker for monitoring disease progression or the effects of therapeutic interventions. High test-retest reliability of this technique for long observation periods is therefore required to differentiate daily or weekly fluctuations from stable plastic reorganization of corticospinal connectivity. …”
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7735
Sarcopenia and Age-Related Endocrine Function
Published 2012-01-01“…Although IGF-I is a potent regulator of muscle mass, its therapeutic use has not had a positive effect probably due to local IGF-I resistance. …”
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7736
Family intervention for expressed emotion in schizophrenia: Indian context
Published 2023-04-01“…The intervention used methods of social case and group work, social work principles, and therapeutic activities. The methodologies adopted a brainstorming technique, case vignettes, role plays, and video clippings concerning the topics of the day. …”
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7737
Non-coding RNAs participate in interactions between senescence and gastrointestinal cancers
Published 2025-01-01“…We are keen to identify prognostic or therapeutic targets for gastrointestinal cancers from, i.e., aging-related ncRNAs, or discover novel strategies to treat and manage in the elderly. …”
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7738
Chronic asymptomatic orchitis in dogs alters Sertoli cell number and maturation status
Published 2025-02-01“…The results indicate the need to restore Sertoli cell function as a potential therapeutic target for a successful restart of spermatogenesis.…”
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7739
Neurocranial Pharmacodialysis Device for subarachnoid hemorrhage treatment—a perspective
Published 2024-02-01“…This neuroengineered system, implantable in the neurocranium, can perform subarachnoid drug delivery, edema drainage, neurotoxin dialysis, and electroencephalography (EEG) recording for years, hence its therapeutic potential in SAH as a Neurocranial Pharmacodialysis Device (NPD). …”
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7740
Prenatal Acetaminophen Exposure and its Associated Risk for Attention Deficit Hyperactivity Disorder
Published 2024-11-01“…It has maintained an excellent reputation as a safe therapeutic in several types of patient profiles. However, the number of children diagnosed with neurodevelopmental disorders, namely ADHD, have been on the rise. …”
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