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7701
Antibody dynamics in dogs submitted to different canine visceral leishmaniasis treatment protocols
Published 2025-01-01“…Therefore, it is necessary to complement the methods of clinical and therapeutic monitoring of dogs with CVL in order to establish the risk of transmissibility of the agent in infected and treated dogs.…”
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7702
Targeting glycolysis: exploring a new frontier in glioblastoma therapy
Published 2025-01-01“…Additionally, this review systematically analyzes potential therapeutic strategies targeting key molecules within the glycolytic pathway, such as Glucose Transporters (GLUTs), Monocarboxylate Transporters(MCTs), Hexokinase 2 (HK2), 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 (PFKFB3), Pyruvate Kinase Isozyme Type M2 (PKM2), and the Lactate Dehydrogenase A (LDHA). …”
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7703
Evaluation of Nutritional Supplements on Periodontal Fibroblast in Systemic Disease Conditions: An In Vitro Study
Published 2024-12-01“…These supplements may serve as adjunctive therapeutic options for managing periodontal disease in individuals with systemic comorbidities.…”
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7704
Tackling Extended Hospital Stays in Patients with Acute Bacterial Skin and Skin Structure Infections
Published 2022-09-01“…In conclusion, while the burden of ABSSSI is rising, new treatment options provide additional therapeutic choice, although pharmacoeconomic considerations might limit use in some cases.…”
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7705
Role of Subcutaneous Adipose Tissue in the Pathogenesis of Insulin Resistance
Published 2013-01-01“…It is important to shift focus from fat content to functional heterogeneity in adipose tissue depots to better understand the relative role of subcutaneous adipose tissue in metabolic complications of obesity. Therapeutic lifestyle change continues to be the most important intervention in clinical practice at any level of increased adiposity. …”
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7706
Promotion Mechanisms of Stromal Cell-Mediated Lung Cancer Development Within Tumor Microenvironment
Published 2025-02-01“…Stromal cells within the TME hold potential as therapeutic targets for lung cancer treatment. However, the precise and comprehensive mechanisms by which stromal cells contribute to lung cancer progression have not been fully elucidated. …”
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7707
Exploring the Use of the Therapist’s Self in Therapy: A Systematic Review
Published 2025-01-01“…Findings: All studies that met the inclusion criteria were from the West. Therapeutic self-disclosure (TSD) emerged as the primary way through which therapists used their self in therapy—notably, the only way documented in the studies reviewed. …”
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7708
How close is autophagy-targeting therapy for Alzheimer's disease to clinical use? A summary of autophagy modulators in clinical studies
Published 2025-01-01“…Modulating autophagy has been proposed as a therapeutic strategy for AD because of its potential to clear aggregated proteins. …”
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7709
Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors...
Published 2025-01-01“…Future work will include the synthesis of these molecules followed by in-depth in vitro and in vivo testing to validate their potential therapeutic efficacy.…”
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7710
Successful Diagnosis and Management of Superior Orbital Fissure Syndrome Secondary to Lung Adenocarcinoma: A Case Report
Published 2025-01-01“…This case underscores the diagnostic and therapeutic challenges associated with such rare metastatic presentations.Case Presentation: A 60-year-old woman with a history of left lung adenocarcinoma presented with left eyelid ptosis and fixed eye position following hair dyeing. …”
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7711
De la Mer du Nord à la Méditerranée, l’imaginaire maritime des Victoriens
Published 2017-03-01“…From the end of the 18th century, the sea is construed in the Western imagination as the original universe, whose therapeutic virtues are being discovered. The location of the sea in question sets at the same time the property of its waters and the relationship which it offers to the body of the swimmers: a healthy and virile confrontation in the North, a degenerative merging in the South. …”
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7712
Exosomal insights into ovarian cancer stem cells: revealing the molecular hubs
Published 2025-01-01“…These findings highlight potential biomarkers for early detection and therapeutic targets.…”
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7713
Hydromethanolic extracts of Morus alba L. (Mulberry) young and ripe fruit induces apoptosis in lung carcinoma cells (A549)
Published 2025-01-01“…Cancer ranking as the second leading cause of global mortality, it is essential to investigate natural compounds like phytochemicals for therapeutic benefits. The research investigates presence of phytochemicals and antioxidant activity of both young (MAF-Y) and ripe (MAF-R) mulberry fruit extracts. …”
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7714
Unusual Case of Extraction of Maxillary Lateral Incisors and Mandibular Central Incisors
Published 2017-01-01“…This article’s purpose is to report a case where maxillary lateral incisors and mandibular central incisors are extracted and a canine substitution was performed as the best therapeutic option in order to obtain symmetry in a malocclusion with an upper lateral incisor with poor prognostic, solve moderate crowding, get enough space for the permanent dentition, and provide stability to the results. …”
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7715
In Vivo Bioluminescence Imaging Validation of a Human Biopsy–Derived Orthotopic Mouse Model of Glioblastoma Multiforme
Published 2013-05-01“…The model may thus be routinely used for the assessment of novel anti-GBM therapeutic approaches implementing well-established and cost-effective optical imaging strategies.…”
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7716
Sex-Related Effects of Adrenergic Drugs on Conditioned Pain Modulation: A Randomized Controlled Cross-Over Double-Blind Trial
Published 2022-01-01“…It will be interesting to verify if the same results are present in patients suffering from chronic pain and if adrenergic agonists could have better therapeutic effects in women showing reduced CPM effectiveness.…”
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7717
Sediaan Obat Kumur Dalam Bentuk Teh Celup Dari Daun Teh Hijau, Daun Sirih, Dan Kayu Manis
Published 2023-11-01“…Mouthwash is a solution or liquid used to rinse the oral cavity that has benefits for eliminating harmful bacteria, removing unpleasant odors (halitosis), providing therapeutic effects, and eliminating or preventing dental caries, as well as for aesthetics and freshness. …”
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7718
Once-Daily Dosing of Aminoglycosides
Published 1994-01-01“…DATA SOURCES: Published articles on the pharmacodynamics of aminoglycosides and those comparing the therapeutic efficacy and toxicity of once-daily administration will more frequent closing regimens. …”
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7719
Righting response and electrocardiographic evaluation of juvenile tambaqui (Colossoma macropomum) (Cuvier, 1818) exposed to immersion baths with different concentrations of bushy l...
Published 2025-01-01“…This study aims to evaluate the anesthetic activity of Lippia alba essential oil (LAEO) to propose a therapeutic window for its use in tambaqui (C. macropomum). …”
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7720
Study of Brain-derived Neurotrophic Factor in Drug-naive Patients with Schizophrenia
Published 2024-05-01“…Conclusion: The index study found BDNF levels to be reduced in patients of schizophrenia and BDNF was found to correlate with severity of illness, especially positive symptoms. Thus, developing therapeutic strategies that can activate BDNF signaling may prove beneficial in improving the clinical outcome of schizophrenia.…”
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