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  1. 7661

    Emerging Prospects for Nanoparticle-Enabled Cancer Immunotherapy by Manal Ali Buabeid, El-Shaimaa A. Arafa, Ghulam Murtaza

    Published 2020-01-01
    “…This review not only describes the modes of cancer immunotherapy to reveal the importance of nanoparticles in this modality but also narrates nanoparticle-mediated delivery of cancer antigens and therapeutic supplements. Moreover, the impact of nanoparticles on the immunosuppressive behavior of tumor environment has been discussed. …”
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  2. 7662

    Effectiveness of Plasma Therapy in Patients with COVID-19 Infection – A Retrospective Record-based Descriptive Study by Murali Shankar Bhat, Sripada G. Mehandale, Raghavendra R. Huchchannavar

    Published 2024-12-01
    “…Introduction: The COVID-19 pandemic presented an unprecedented challenge to the medical community, leading to numerous therapeutic interventions being explored. Convalescent plasma therapy (CPT), derived from recovered COVID-19 patients, was one such treatment used in the absence of proven therapies. …”
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  3. 7663

    Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

    Published 2025-02-01
    “…Conclusions These results demonstrated that curcumin inhibits growth and triggers apoptosis of human CRPC cells via the IGF-1/PI3K/Akt pathway, thus providing potential new therapeutic strategies for PCa and CRPC.…”
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  4. 7664

    AXL inhibitors selected by molecular docking: Option for reducing SARS-CoV-2 entry into cells by Galindo-Hernández Octavio, Vique-Sánchez José Luis

    Published 2022-09-01
    “…It is, therefore, necessary to propose specific pharmacological treatments against COVID-19. A new therapeutic target on the human cellular membrane is AXL (anexelekto), proposed as an independent pathway by which interaction with the S protein of SARS-CoV-2 allows the virus to enter the cell, without the participation of ACE2. …”
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  5. 7665

    Inflammation, immunity, and vaccines by R. Gong, M. Gerhard

    Published 2024-09-01
    “…Understanding the mechanisms of inflammation and immunity induced by H. pylori is crucial for developing preventive and therapeutic vaccines. This review captures the major advancements in H. pylori-induced inflammation, immunity, and vaccine development from April 2023 to March 2024. …”
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  6. 7666

    Efficacy of Intra Sheath Corticosteroid Injection in Treatment of De Quervain Disease by Qasim Mahmood, Sheraz Mustafa, Sarmad Nasir, Noman Khalid

    Published 2024-09-01
    “…This highlights the significant advantages that local steroid injections have over conventional pain management techniques, making them a desirable and effective therapeutic choice for individuals coping with the difficulties associated with De Quervain's disease. …”
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  7. 7667

    Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin. by Jahan Abdi, Frank Redegeld

    Published 2025-01-01
    “…The findings of this study imply that activation of TLR1/2 downregulates FLC production in MM cells even in the context of bone marrow microenvironment components and suggest that targeting some TLRs such as TLR1/2 might have therapeutic potential.…”
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  8. 7668

    Differentially regulated ADAMTS1, 8, 9, and 18 in pancreas adenocarcinoma by Murat Özgür Kılıç, Büşra Aynekin, Mikdat Bozer, Adem Kara, Hacer Haltaş, Duygu İçen, Kadir Demircan

    Published 2017-12-01
    “…Introduction : Despite recent diagnostic and therapeutic improvements, pancreas cancer remains one of the highly lethal cancers. …”
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  9. 7669

    Hydrocephaly management in patients with tumors in the posterior fossa. by Osmany Morales Sabina, José Ramón Tejera del Valle, Juan Francisco Piñeiro Martí., Omar López Arbolay.

    Published 2005-08-01
    “…<strong>Objective: </strong>To determine the presence of hidrocephalia in the tumors of the PF and the therapeutic focus in our means. <strong>Methods: </strong>We report a descriptive, retrospective study of 10 adult patients with posterior fossa mass lesions and obstructive hydrocephalus who were managed medically for compensate intracranial hypertension plus observation and were operated through posterior fossa craniectomy and tumor excision as unique method of surgical treatment. …”
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  10. 7670

    The discovery of high endothelial venules. A historical note by Domenico Ribatti

    Published 2025-03-01
    “…However, although many aspects of HEVs are still to be discovered, their therapeutic modulation already offers interesting results, especially for cancer treatment.…”
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  11. 7671

    Regulatory Role of CD4+ T Cells in Myocarditis by Daria Vdovenko, Urs Eriksson

    Published 2018-01-01
    “…Understanding the specific roles of these T cell populations at different stages of the disease progression might provide a key for the development of successful therapeutic strategies.…”
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  12. 7672

    Chemokines in Renal Diseases by Stephan Segerer, Peter J. Nelson

    Published 2005-01-01
    “…In animal models, chemokines are produced at the site of injury, leading to inflammatory cell recruitment. The therapeutic impact of the blockade of CCR1, CCR2, CCR4, CCR5, or the corresponding ligands has been further studied in various renal disease models. …”
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  13. 7673

    Current trends of Carbapenemase Production Amongst Multi-drug Resistant Gram-Negative Bacteria in a Tertiary-Care Hospital in West Bengal by Arunima Chakravarty, Raja Ray, Ananda S. Mondal, Hirak J. Raj

    Published 2025-01-01
    “…Early detection of resistance, stringent infection prevention and control measures and antimicrobial stewardship are essential to preserve the usefulness of Carbapenems and improve therapeutic outcomes in patients. …”
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  14. 7674

    Recent Advances in Metal–Organic Framework-Based Anticancer Hydrogels by Preeti Kush, Ranjit Singh, Parveen Kumar

    Published 2025-01-01
    “…These numbers cause massive, physical, emotional, and financial burdens to society and the healthcare system that lead to further research for a better and more effective therapeutic strategy to manage cancer. Metal–organic frameworks (MOFs) are promising alternative approaches for efficient drug delivery and cancer theranostics owing to their unique properties and the direct transportation of drugs into cells followed by controlled release, but they suffer from certain limitations like rigidity, poor dispersibility, fragility, aggregation probability, and limited surface accessibility. …”
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  15. 7675

    Research progresses and hotspots on glucose metabolic reprogramming in breast cancer: a bibliometric analysis over the past two decades by Lei Huang, Wenyue Zhao, Lamei Sun, Dong Niu, Xiaodan Zhu, Chunhui Jin

    Published 2025-01-01
    “…Keyword analysis suggested that the mechanisms of glucose metabolism reprogramming in BC and related therapeutic strategies were the research hotspots.ConclusionThis study, for the first time, elucidated the progresses and hotspots of in the research on glucose metabolism reprogramming in BC, highlighting its potential role in treating BC. …”
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  16. 7676

    A Reflection of the Position that Social Work Played in Tackling Coronavirus in South Africa by Simon Murote Kang’ethe

    Published 2024-12-01
    “…This researcher thinks that social workers during the COVID era achieved the following: Fighting coronavirus-driven poverty, facilitating psychosocial therapeutic interventions, such as counseling to the victims of gender-based violence, mobilized communities to embrace the spirit of Ubuntu, and offering caregiving to those infected. …”
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  17. 7677

    Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy by Man C, An Y, Wang GX, Mao EQ, Ma L

    Published 2025-01-01
    “…Different mechanisms underlying sepsis-related coagulopathy are discussed, including factors contributing to the imbalance of pro- and anticoagulation relevant to endothelial cells. The potential therapeutic implications of anticoagulants on these mechanisms are discussed. …”
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  18. 7678

    ATM in immunobiology: From lymphocyte development to cancer immunotherapy by Ji-Hoon Lee

    Published 2025-02-01
    “…This review synthesizes current knowledge on ATM's functions in the immune system, offering insights into the pathophysiology of ATM-related disorders and potential therapeutic strategies for immune-related conditions and cancer immunotherapy.…”
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  19. 7679

    Moringa oleifera Supplemented Diets Prevented Nickel-Induced Nephrotoxicity in Wistar Rats by O. S. Adeyemi, T. C. Elebiyo

    Published 2014-01-01
    “…The Moringa oleifera plant has been implicated for several therapeutic potentials. Objective. To evaluate whether addition of M. oleifera to diet has protective effect against nickel-induced nephrotoxicity in rats. …”
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  20. 7680

    Sulfated and Phosphorylated Agarose as Biomaterials for a Biomimetic Paradigm for FGF-2 Release by Aurelien Forget, V. Prasad Shastri

    Published 2024-12-01
    “…Local delivery of growth factors (GFs) involved in angiogenesis such as fibroblast blast growth factor-2 (FGF-2) has been shown to trigger collateral neovasculature and might lead to a therapeutic strategy. In vivo, heparin, a sulfated polysaccharide present in abundance in the extracellular matrix (ECM), has been shown to function as a local reservoir for FGF-2 by binding FGF-2 and other morphogens and it plays a role in the evolution of GF gradients. …”
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