Tracheal adenoid cystic carcinoma presenting as a locally advanced thyroid gland carcinoma by Mariam Ben Ayed, MD, Makram Tbini, MD, Inès Riahi, MD, Sarra Idriss, MD, Mamia Ben Salah, MD

“…After a follow-up period of 2 years, the tumor remained stable, and the patient receivedThis study aims to determine the clinical, radiological, and therapeutic aspects of advanced adenoid cystic carcinoma.…”
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Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats by Martha Isela Barragán-Bonilla, Juan Miguel Mendoza-Bello, Penélope Aguilera, Isela Parra-Rojas, Berenice Illades-Aguiar, Mónica Ramírez, Mónica Espinoza-Rojo

“…Animal models have been very useful for the study of this disease and to search for new therapeutic targets that delay, attenuate, or avoid diabetic complications. …”
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TNF inhibitors target a mevalonate metabolite/TRPM2/calcium signaling axis in neutrophils to dampen vasculitis in Behçet’s disease by Menghao Zhang, Na Kang, Xin Yu, Xiaoyang Zhang, Qinghui Duan, Xianqiang Ma, Qiancheng Zhao, Zhimian Wang, Xiao’ou Wang, Yeling Liu, Yuxiao Zhang, Can Zhu, Ruiyu Gao, Xin Min, Cuifeng Li, Jin Jin, Qian Cao, Rongbei Liu, Xiaoyin Bai, Hong Yang, Lidan Zhao, Jinjing Liu, Hua Chen, Yonghui Zhang, Wanli Liu, Wenjie Zheng

“…Here we report an unexpected mechanism underlying the therapeutic effects of TNF inhibitors in Behçet’s disease (BD), an autoimmune inflammatory disorder. …”
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Baicalein inhibits NLRP3 inflammasome activation and mitigates placental inflammation and oxidative stress in gestational diabetes mellitus by Yao Jun, Pan Jiaying, Jiang Qiaoying, Wang Hui, Zhao Yiqi

“…These findings provide valuable insights into the potential therapeutic role of Baicalein in managing GDM.…”
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Microfluidic organ-on-chip systems for periodontal research: advances and future directions by Gopu Sriram, Gopu Sriram, Hardik Makkar, Hardik Makkar

“…We discuss the critical engineering and biological considerations in designing these platforms, their applications in studying oral biofilms, periodontal tissue responses, and their potential to unravel disease mechanisms and therapeutic targets in periodontal disease.…”
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Bacteria as Precision Tools for Cancer Therapy by Carmen Michán, José Prados, Juan‐Luis Ramos

“…This progress, along with recent insights into how cancer cells evade immune response, has prompted innovative therapeutic approaches. Tumour microenvironments are typically nutrient‐rich, characterised by low oxygen tensions and very resistant to immune responses. …”
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Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers by Salman M. Toor, Eyad Elkord

“…Taken together, this work suggests that CRC patients may benefit more from the development of therapeutic agents to promote myeloid cell differentiation or inhibition for the reversal of immune suppression.…”
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Hepatoid adenocarcinoma of the stomach with ideal response to neoadjuvant chemo-immunotherapy: a case report by Linchuan Li, Linchuan Li, Dexu Zhang, Jiankang Zhu, Jiankang Zhu, Guangyong Zhang, Guangyong Zhang

“…This is the first report of chemotherapy combined with sintilimab in the treatment of gastric hepatoid adenocarcinoma, which may provide novel insights into the therapeutic strategy for HAS.…”
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Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy by Chao Chen, Lirong Tan, Wu Zhu, Li Lei, Yehong Kuang, Panpan Liu, Jie Li, Xiang Chen, Cong Peng

“…IL-21 may be a potential therapeutic target in psoriasis.…”
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Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine by Jiming Guo, Zhijie Huang, Qinjing Wang, Min Wang, Yue Ming, Weixing Chen, Yisheng Huang, Zhengming Tang, Mingshu Huang, Hongyu Liu, Bo Jia

“…Although engineered EVs demonstrate excellent therapeutic efficacy, challenges such as low production yield and the complexity of engineering modifications constrain their further clinical applications. …”
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Research progress on platelets in glioma by Mingrong Zuo, Tengfei Li, Zhihao Wang, Yufan Xiang, Siliang Chen, Yanhui Liu, Xiangxiang Pan

“…TEPs can be used to obtain genetic information about gliomas, which is helpful for early diagnosis and monitoring of therapeutic effects. Platelet membranes are intriguing biomimetic materials for developing efficacious drug carriers to enhance antiglioma activity. …”
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PDPN+ cancer‐associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF‐κB activation and the CCL2‐ACKR1 axis by Zhenxiong Zhao, Hui Sun, Yingxue Liu, Yanqiu Zhang, Xin Wang, Xu Wang, Cong Tan, Shujuan Ni, Weiwei Weng, Meng Zhang, Lei Wang, Dan Huang, Wenchao Gu, Jinjia Chang, Weiqi Sheng, Mi‐die Xu

“…Together, this study elucidates the mechanism by which PDPN(+) CAFs promote angiogenesis, providing a deeper understanding of the molecular processes underlying CAF‐mediated angiogenesis and suggesting potential therapeutic targets for gastric cancer treatment.…”
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Methods of Control of the Leishmania infantum Dog Reservoir: State of the Art by Michele Podaliri Vulpiani, Luigi Iannetti, Daniela Paganico, Filomena Iannino, Nicola Ferri

“…Treatment of infectious dogs with one of the available therapeutic protocols is recommendable as it allows to reduce parasite burdens and therefore the possibility of transmission of Leishmania infantum to vectors. …”
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Exercise and exerkines: Mechanisms and roles in anti-aging and disease prevention by Xuan Lu, Ying Chen, Yue Shi, Yi Shi, Xianbin Su, Peijie Chen, Die Wu, Hui Shi

“…Additionally, the integration of exercise-induced exerkines into therapeutic strategies represents a promising approach to mitigating age-related pathologies at the molecular level. …”
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Uterine Sarcoidosis: A Rare Extrapulmonary Site of Sarcoidosis by Creticus P. Marak, Narendrakumar Alappan, Amit Chopra, Olena Dorokhova, Sumita Sinha, Achuta K. Guddati

“…Isolated occurrence of sarcoidosis in the genital system is rare and poses a diagnostic and therapeutic dilemma. Uterine sarcoidosis can present with cervical erosions, endometrial polypoid lesions, and recurrent serometra. …”
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Therapies with Emerging Evidence of Efficacy: Avotermin for the Improvement of Scarring by Jim Bush, Karen So, Tracey Mason, Nick L. Occleston, Sharon O'Kane, Mark W. J. Ferguson

“…Differences in wound healing and scar outcome between early fetal and adult wounds led to interest in the role of the TGFβ family of cytokines in scar formation and the identification of TGFβ3 (avotermin) as a potential therapeutic agent for the improvement of scar appearance. …”
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Citrulline – The Powerhouse Nutrient for Cardiometabolic and Brain Health by Daria Pedrycz, Mateusz Drabczyk, Emilia Pedrycz, Karolina Karoń, Grzegorz Drapała, Wojciech Grabowski, Łukasz Karoń, Anna Zygmunt, Sławomir Karoń

“…This review synthesizes current knowledge on citrulline's mechanisms, therapeutic potential, and broader implications for aging and vascular health. …”
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Progression of Voice and Speech Impairment in the Course of Parkinson's Disease: A Longitudinal Study by S. Skodda, W. Grönheit, N. Mancinelli, U. Schlegel

“…Further investigations are warranted to get a better insight into the dynamics of the progression of voice and speech impairment in PD as a precondition for the development of therapeutic approaches.…”
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Cost-effectiveness analysis of eribulin versus dacarbazine in patients with advanced liposarcoma by Miaomiao Zhang, Jinlong Huang, Xiaochun Zheng, Ping Huang, Xiuli Yang

“…Abstract A subgroup analysis of a randomized study demonstrated that patients with advanced or metastatic liposarcoma treated with eribulin had longer overall survival and progression-free survival compared to those treated with dacarbazine, suggesting eribulin as a therapeutic option for advanced liposarcoma. Therefore, this study aims to evaluate the cost-effectiveness of eribulin versus dacarbazine in the treatment of advanced liposarcoma. …”
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Use of integrative and complementary practices and the quality of life of undergraduate nursing students by Gabrielli Sousa dos Santos, Marcella Cecílio de Almeida, Raquel Valente de Souza, Joyce Assunção Barros, Adriana Cristina Nicolussi

“…A sociodemographic/clinical-therapeutic questionnaire and the WHOQOL-Bref instrument were used. …”
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