Targeting lipid metabolism: novel insights and therapeutic advances in pancreatic cancer treatment by Yanyan Zhang, Zhichao Yang, Yuchen Liu, Jinjin Pei, Ruojie Li, Yanhui Yang

“…Given these limitations, new therapeutic approaches are being developed to target tumor metabolism. …”
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Stem Cell-Based Therapeutic Approaches to Restore Sensorineural Hearing Loss in Mammals by Muhammad Waqas, Iram Us-Salam, Zainab Bibi, Yunfeng Wang, He Li, Zhongshou Zhu, Shuangba He

“…In this review, we specifically discuss the potential of different kinds of stem cells that hold the potential to restore sensorineural hearing loss in mammals and comprehensively explain the current therapeutic applications of stem cells in both the human and mouse inner ear to regenerate/replace the lost hair cells and spiral ganglion neurons.…”
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Therapeutic Levels of Acetaminophen Causing AKI: A Case Report and Literature Review by Hamnah Tayyab, Lavanya Dhondapati, Ashraf Ullah, Mohammed Dheyaa Marsool Marsool, Singh Jagmeet, Khabab Abbasher Hussien Mohamed Ahmed

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Effect of surface hydrophobicity of therapeutic protein loaded in polyelectrolyte nanoparticles on transepithelial permeability by Miklavžin Ana, Cegnar Mateja, Kerč Janez, Kristl Julijana

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Application of Mild Therapeutic Hypothermia on Stroke: A Systematic Review and Meta-Analysis by Shaheen E. Lakhan, Fabricio Pamplona

“…Body temperature on hospital admission is an important predictor of clinical outcome. Therapeutic hypothermia is promising in clinical settings for stroke neuroprotection. …”
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Toll-Like Receptor 4: A Promising Therapeutic Target for Alzheimer’s Disease by Linyu Wu, Xiaohui Xian, Guangyu Xu, Zixuan Tan, Fang Dong, Min Zhang, Feng Zhang

“…Elucidating the regulatory mechanism of TLR4 in AD may provide valuable clues for developing new therapeutic strategies for AD.…”
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Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects by Sang Eon Park, Hyeong Seop Kim, Soo Jin Kwon, Min-Jeong Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Duk L. Na, Jong Wook Chang

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Comparison of centrifugal-membrane hybrid plasmapheresis and centrifugation therapeutic plasma exchange in hyperlipidemia by ZHANG Bin, WU Chunxi, ZHOU Yumeng, ZHOU Fang, YI Zhongmei

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Factors influencing therapeutic efficacy of denosumab against osteoporosis in systemic lupus erythematosus by Sung-Hwan Park, Seung-Ki Kwok, Wan-Uk Kim, Ji Hyeon Ju, Jiwon Yang, Youngjae Park, Jennifer Jooha Lee

“…This study aimed to evaluate the therapeutic efficacy of denosumab in patients with SLE with osteoporosis and to analyse the factors influencing therapeutic efficacy.Methods A total of 166 patients with SLE with osteoporosis who initiated denosumab between January 2016 and December 2023 were included. …”
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Serratia marcescens peritoneal dialysis peritonitis: a clinical case and therapeutic approach by Hmaidouch Nabil, Yacoubi Qods, Dkhissi Rihab, Ouzeddoun Naima, Benamar Loubna

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Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19 by Aurelie Guironnet-Paquet, Aurelie Guironnet-Paquet, Hind Hamzeh-Cognasse, Frederic Berard, Fabrice Cognasse, Fabrice Cognasse, Jean Christophe Richard, Hodane Yonis, Mehdi Mezidi, Olivier Desebbe, Bertrand Delannoy, Sophie Demeret, Clemence Marois, Clemence Marois, Clemence Marois, Samir Saheb, Quoc Viet Le, Mathieu Schoeffler, Paul Simon Pugliesi, Sophie Debord, Paul Bastard, Paul Bastard, Paul Bastard, Paul Bastard, Aurélie Cobat, Aurélie Cobat, Aurélie Cobat, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Rémi Pescarmona, Sébastien Viel, Jean François Nicolas, Jean François Nicolas, Audrey Nosbaum, Audrey Nosbaum, Marc Vocanson, Olivier Hequet, Olivier Hequet

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Identification of ferroptosis-related signature predicting prognosis and therapeutic responses in pancreatic cancer by Ting Ting Chung, Zanyue Piao, Seung Jin Lee

“…Abstract Ferroptosis plays a role in tumorigenesis by affecting lipid peroxidation and metabolic pathways; however, its prognostic or therapeutic relevance in pancreatic adenocarcinoma (PAAD) remains poorly understood. …”
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Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma by Pengfei Zan, Yi Zhang, Yidong Zhu, Qingjing Chen, Zhengwei Duan, Yonghao Guan, Kaiyuan Liu, Anquan Shang, Zihua Li

“…The results of this study hold promise for developing therapeutic strategies tailored to the unique characteristics of SARC.…”
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From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents by Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse, Hamada Hashem

“…This review explores progress in developing ciprofloxacin derivatives with anticancer properties, emphasizing key structural changes that improve their therapeutic effectiveness by modifying the basic group at position 7, the carboxylic acid group at position 3, or both. …”
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Therapeutic Activity of Lenalidomide in Mantle Cell Lymphoma and Indolent Non-Hodgkin’s Lymphomas by Marco Gunnellini, Lorenzo Falchi

“…The role of lenalidomide in the therapeutic armamentarium of patients with indolent NHL or MCL will be discussed in the present paper.…”
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Tumor-infiltrating regulatory T cell: A promising therapeutic target in tumor microenvironment by Tianning Huang, Fan Li, Yiming Wang, Jian Gu, Ling Lu, Peifang Wei

“…In this review, we summarize novel therapeutic approaches targeting both the metabolic pathways and hallmarks of TI-Tregs in preclinical and clinical studies. …”
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FORCED HAPPINESS AS A MODERN SOCIO AND CULTURAL IMPERATIVE by H. V. Khodus

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Nonviral targeted mRNA delivery: principles, progresses, and challenges by Xi He, Guohong Li, Letao Huang, Haixing Shi, Sha Zhong, Siyu Zhao, Xiangyu Jiao, Jinxiu Xin, Xiaoling Yin, Shengbin Liu, Zhongshan He, Mengran Guo, Chunli Yang, Zhaohui Jin, Jun Guo, Xiangrong Song

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Effect of the size of nucleic acid delivery systems on their fate in cancer treatment by Mengyun Ye, Junni Gong, Wang Chen, Xiaoxuan Liu, Dandan Zhu

Subjects: “…nucleic acid therapeutics…”
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Angiopoietin-like protein 4 dysregulation in kidney diseases: a promising biomarker and therapeutic target by Yan Li, Yan Li, Yan Li, Yuxin Zhang, Yuxin Zhang, Yuxin Zhang, Mengxia Cao, Mengxia Cao, Mengxia Cao, Tingting Yuan, Tingting Yuan, Tingting Yuan, Santao Ou, Santao Ou, Santao Ou

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