Unraveling the Complex Relationship Triad between Lipids, Obesity, and Inflammation by Shahida A. Khan, Ashraf Ali, Sarah A. Khan, Solafa A. Zahran, Ghazi Damanhouri, Esam Azhar, Ishtiaq Qadri

“…Increases in mortality and morbidity in obesity related inflammation have initiated studies to explore different lipid mediated molecular pathways of attempting resolution that uncover newer therapeutic opportunities of anti-inflammatory components. …”
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Comparison of Globus Pallidus Interna and Subthalamic Nucleus in Deep Brain Stimulation for Parkinson Disease: An Institutional Experience and Review by Shazia Mirza, Umar Yazdani, Richard Dewey III, Neepa Patel, Richard B. Dewey, Svjetlana Miocinovic, Shilpa Chitnis

“…Deep Brain Stimulation (DBS) has revolutionized the lives of patients of Parkinson disease, offering therapeutic options to those not benefiting entirely from medications alone. …”
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Pharmacological Evaluation of Antidepressant-Like Effect of Genistein and Its Combination with Amitriptyline: An Acute and Chronic Study by Gaurav Gupta, Tay Jia Jia, Lim Yee Woon, Dinesh Kumar Chellappan, Mayuren Candasamy, Kamal Dua

“…Genistein at its standard dose (10 mg/kg) rendered synergistic effects in combination with subeffective dose of amitriptyline (5 mg/kg) and additive effects in combination with therapeutic dose of amitriptyline (10 mg/kg).…”
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Nicotinamide Adenine Dinucleotide Phosphate Oxidases and Metabolic Dysfunction-Associated Steatotic Liver Disease by Vittoria Cammisotto, Emanuele Valeriani, Pasquale Pignatelli, Francesco Violi

“…This review aims to summarize the current knowledge on the involvement of oxidative stress in the MASLD–MASH transition, focusing on the role of NOX isoforms, and to suggest targeting NOX as a therapeutic approach in MASLD.…”
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A Role for Folate in Microbiome-Linked Control of Autoimmunity by Christine Mölzer, Heather M. Wilson, Lucia Kuffova, John V. Forrester

“…Hence, folate supplementation has potential prophylactic and/or therapeutic benefit in AID/AD.…”
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Wolff-Parkinson-White Syndrome Mimics a Conduction Disease by S. Marrakchi, I. Kammoun, S. Kachboura

“…This can lead to diagnostic and therapeutic dilemmas in the context of syncope.…”
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Significant Depletion of CD4+ T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4+ T Cell Reservoir Continuing to Persist in the... by Jeffy George, Wendeline Wagner, Mark G. Lewis, Joseph J. Mattapallil

“…However, a minor fraction of repopulating CD4+ T cells harbored SIV DNA suggesting that the viral reservoir continues to persist in the oral mucosa during ART. Therapeutic approaches aimed at obtaining sustainable CD4+ T cell repopulation in combination with strategies that can eradicate the latent viral reservoir in the oral mucosa are essential for better oral health and long-term outcome in HIV infected patients.…”
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Effectiveness and Mechanisms of Low-Intensity Pulsed Ultrasound on Osseointegration of Dental Implants and Biological Functions of Bone Marrow Mesenchymal Stem Cells by Chao Liang, Xiu Liu, Yuwei Yan, Rongxin Sun, Jun Li, Wei Geng

“…Although many challenges need to be overcome in the future, LIPUS is bound to be an efficient and convenient therapeutic method to improve the dental implantation success rate and expand clinical implant indications.…”
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Working Together and Being Physically Active Are Not Enough to Advise Uniformly and Adequately Low Back Pain Patients: A Cross-Sectional Study by C. Praz, J. Ducki, M. L. Connaissa, P. Terrier, P. Vuistiner, B. Léger, F. Luthi

“…Conversely, interdisciplinarity seeks to challenge such differences, so that the patient receives one single and consistent therapeutic message. Some studies also suggest associations between HCPs life habits and recommendations. …”
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Autonomous Defense Based on Biogenic Nanoparticle Formation in Daunomycin-Producing <i>Streptomyces</i> by Karel Beneš, Vladislav Čurn, Baveesh Pudhuvai, Jaroslav Motis, Zuzana Michalcová, Andrea Bohatá, Jana Lencová, Jan Bárta, Michael Rost, Andreas Vilcinskas, Vladimír Maťha

“…Further investigation will help to refine microbial production systems for daunomycin and also broaden the application of similar strategies for the synthesis of other therapeutically important compounds.…”
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Anti-Biofilm Agents to Overcome <i>Pseudomonas aeruginosa</i> Antibiotic Resistance by Marie Hanot, Elodie Lohou, Pascal Sonnet

“…Given the selection pressure imposed by conventional antibiotics, a new therapeutic strategy has emerged that aims at reducing bacterial virulence without inhibiting cell growth. …”
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Molecular Insights in the Anticancer Activity of Natural Tocotrienols: Targeting Mitochondrial Metabolism and Cellular Redox Homeostasis by Raffaella Chiaramonte, Giulia Sauro, Domenica Giannandrea, Patrizia Limonta, Lavinia Casati

“…This evidence sheds light on the use of these natural compounds as a promising preventive or therapeutic approach for novel anticancer strategies.…”
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Optical and MRI Multimodal Tracing of Stem Cells In Vivo by Jia Yang, Min Yan, Zhong Wang, Cong Zhang, Miao Guan, Zhenglong Sun

“…However, due to the technical limitations of the in vivo visualization of transplanted stem cells, the therapeutic mechanisms and biosafety of stem cells in vivo are poorly defined, which limits the speed of clinical translation. …”
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Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR by Aixin Yu, Yiqi Wang, Chao Duan, Jun Qin, Miaomiao Liao, Haiyan Zhu, Junrong Lei, Jun Liu, Zehao Yang, Li Yu, Hui Gui, Jinxin Xin, Weiwei Tao, Wendai Bao, Zhiqiang Dong

“…In conclusion, hypoxia-induced circPLOD2a and b are oncogenic regulators of tumour aggressiveness through attenuating the interaction between HuR and XIRP1 in glioblastoma cells and may be potential therapeutic targets for this disease.…”
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Single-cell RNA sequencing elucidates cellular plasticity in esophageal small cell carcinoma following chemotherapy treatment by Qinkai Zhang, Qinkai Zhang, Qinkai Zhang, Ziyu Gao, Ru Qiu, Jizhao Cao, Chunxiao Zhang, Wei Qin, Wei Qin, Meiling Yang, Meiling Yang, Xinyue Wang, Ciqiu Yang, Jie Li, Jie Li, Dongyang Yang, Dongyang Yang

“…This study elucidates the complex dynamics of cellplasticity in SCCE following chemotherapy, providing new insights and identifyingpotential therapeutic targets to enhance treatment efficacy.…”
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Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis by Georgiana-Iulia Lupu, Emoke Pall, Mihai Cenariu, Monica Irina Nan, Sanda Andrei

“…These metabolites are implicated in both the therapeutic and adverse effects of the drug. The objective is to elucidate the mechanisms of potential hepatotoxicity, with a focus on cell viability and apoptosis. …”
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Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases by Lei Tian, Ruixiang Zhao, Xinyi Xu, Zhiwei Zhou, Xiaofang Xu, Dongmei Luo, Zhiqiang Zhou, Yu Liu, Ariel Kushmaro, Robert S. Marks, András Dinnyés, Qun Sun

“…The present study provides an overview of the preventive and therapeutic effects of L. plantarum on diabetes, obesity, non-alcoholic fatty liver disease, kidney stone disease, and cardiovascular diseases in animal models and human clinical trials. …”
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Assistance for the Prescription of Nutritional Support Must Be Required in Nonexperienced Nutritional Teams by Mehdi Ouaïssi, Philippe Grandval, Diane Mege, Anamaria Nedelcu, Gaëlle Hautefeuille, Frédéric Vanhoeve, Bernard Sastre, Igor Sielezneff, Jacques di Costanzo

“…Assessing the degree of malnutrition of the patient, the therapeutic decision and the type of product prescribed by the doctors were secondarily compared to the proposals of a structured computer program according to the criteria and standards established by the institutions currently recognized. …”
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The impact of aging on neutrophil functions and the contribution to periodontitis by Zi Wang, Anish Saxena, Wenbo Yan, Silvia M. Uriarte, Rafael Siqueira, Xin Li

“…This review could help us better understand the pathogenesis of periodontitis, which could offer novel therapeutic targets for periodontitis.…”
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Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19, clinical characteristics: A multi-center observational study from Jordan by Marwan Shalabi, Salam Ghanem, Iyad Al-Ammouri, Amirah Daher, Enas Al-zayadneh, Alaa Alsmadi, Mais Ayyoub, Samah Abughanam, Mariam Jabr, Montaha Al-Iede

“…Clinical, laboratory, radiological and therapeutic data were collected by retrospective chart review. …”
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