Active ingredients and mechanisms of peony seed blended oil in diabetes treatment using Kunming mice: Insights from GC–MS, network pharmacology, and experimental verification by Yuning Gu, Fengliang Zhong, Tiantian Sun, Zirui Chang

“…The research provides valuable insights into the potential therapeutic use of this blended oil in diabetes management, offering a natural alternative for hypoglycemic treatments. …”
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Uncovering the Mechanisms of BaBaoWuDanYaoMo Against Influenza A Virus and Virus-Induced Inflammation Based on Network Pharmacology and Pharmacological Evaluation by Lei B, Su Y, Chen R, Chen Z, Liu B, Chen Y, Zhou M, Wang X, Ma Q

“…The effect and mechanism of BaBaoWuDanYaoMo (BB) against influenza virus remains obscure. To predict its therapeutic targets via network pharmacology and verify the therapeutic effect and the mechanism of BB against influenza virus in vitro and in vivo.Material and Methods: The potential active and underlying mechanism of BB in the treatment of influenza virus was predicted through network pharmacological strategies and Molecular Docking. …”
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Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal by Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera, Beth Chaplin, Souleymane MBoup, Adam Abdullahi, Adam Abdullahi, Michelle He, Sydney M. Fisher, Sulaimon Akanmu, Charlotte A. Chang, Donald J. Hamel, Ravindra K. Gupta, Ravindra K. Gupta, Phyllis J. Kanki

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Colgajo fasciocutáneo tipo lengüeta medial como alternativa para el manejo de defectos de tejidos blandos en la pierna by X. Ríos Garrido, A. De la Rosa, L. Arzuza Ortega, G. Vargas Lievano, J. Molina Gándara, D.A. Tellez Gamarra, C. Medina Monje

“…Objective: Demonstrate the therapeutic efficacy of the medial tab flap in soft tissue reconstruction on the leg, compared to conventional flaps. …”
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Synergy of rehabilitation for stress-related disorders and ARIs in school-age children under the war condition in Ukraine by I.O. Mityuryayeva-Kornijko, Ie.A. Burlaka, T.D. Klets, O.A. Panchenko, A.V. Kabantseva, E.S. Sukhodolska

“…Results. The synergistic therapeutic effect of the scheme (1+2) showed a significantly better impact on stress-related disorders — sleep disorders, post-traumatic stress disorder, stress-related disorders, quality of life. …”
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Platelet-rich plasma combined with gypenosides for the treatment of psoriasis-like inflammation in mice by LI Dandan, WANG Bing, GE Yu, CHENG Hong, LI Mengxue, WANG Zhicheng, XIA Rong

“…[Objective] To investigate the therapeutic effect of platelet-rich plasma (PRP) subcutaneous injection combined with gypenosides (GPs) oral administration on BALB/c mouse psoriatic inflammation and explore its mechanism of action. …”
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Immune‐dysregulation harnessing in myeloid neoplasms by Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi

“…We also consider both current and novel therapeutic strategies to restore normal immune system function in the context of myeloid malignancies.…”
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Brown Fat and Metabolic Health: The Diverse Functions of Dietary Components by Zachary Brown, Takeshi Yoneshiro

“…Novel mechanistic insights into the control of BAT function and systemic metabolism reveal the therapeutic potential of food-derived compounds for improving metabolic flexibility and insulin sensitivity.…”
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Necrostatin-1 Reduces Neurovascular Injury after Intracerebral Hemorrhage by Melanie D. King, Wittstatt A. Whitaker-Lea, James M. Campbell, Cargill H. Alleyne, Krishnan M. Dhandapani

“…Unfortunately, the dearth of clinically effective treatment options makes ICH the least treatable form of stroke, emphasizing the need for novel therapeutic targets. Recent work by our laboratory identified a novel role for the necroptosis inhibitor, necrostatin-1, in limiting neurovascular injury in tissue culture models of hemorrhagic injury. …”
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Chemical Activation of the Hypoxia-Inducible Factor Reversibly Reduces Tendon Stem Cell Proliferation, Inhibits Their Differentiation, and Maintains Cell Undifferentiation by Alessandra Menon, Pasquale Creo, Marco Piccoli, Sonia Bergante, Erika Conforti, Giuseppe Banfi, Pietro Randelli, Luigi Anastasia

“…Adult stem cell-based therapeutic approaches for tissue regeneration have been proposed for several years. …”
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Physiotherapy Management and Technology Use for Parkinson’s Disease: A Survey Among Greek Physiotherapists by Despoina Papageorgiou, Vasiliki Sakellari, George A. Koumantakis, Viktoria Gkoraki, Nikolaos Chrysagis

“…The purpose of this study is to investigate Greek physical therapists’ perceptions of therapeutic approaches, assessment tools, and the use of technology in the treatment of Parkinson’s disease. …”
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Postoperative Outcome of Combined Phacovitrectomy in Eyes with Excessive Myopia (>-30 D) by Hua Fan, Mingming Zhang, Radouil Tzekov, Zhuyun Qian, Jiasong Yang, XiaoLin Xie, Wensheng Li

“…Our results support the notion that phacoemulsification combined with vitrectomy may be a good therapeutic option for cataracts and vitreous floaters in cases with extreme myopia.…”
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Salidroside enhances 5-fluorouracil sensitivity against hepatocellular carcinoma via YIPF5-induced mitophagy by Sumin Sun, Haili Hu, Feiyu Li, Feiyu Li, Sheng Huan, Long Chen, Jiahui Chen, Peihua Sun, Xiaoqing Dong, Xiaoqing Dong

“…The combination of Sal and 5-FU demonstrated significant therapeutic effects in a mouse HCC model. In conclusion, our study was not only in line with the innovative strategy of drug repurposing, but also important for drug design and natural product screening targeting the relevant pathways.…”
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Ureteroarterial Fistula by D. H. Kim, A. Mahdy, V. Mundra, M. Berman, G. M. Ghoniem

“…Being minimally invasive, we believe that endovascular stenting should be the preferred therapeutic option as it also corrects the source of bleeding while preserving distal blood flow.…”
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Impaired Autophagy of GABAergic Interneurons in Neuropathic Pain by Yuhua Yin, Min-Hee Yi, Dong Woon Kim

“…We discuss relevant research spurring the development of new targets and therapeutic agents of NP and emphasize the need for a multidisciplinary approach to manage NP in the future.…”
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The Pathology of T Cells in Systemic Lupus Erythematosus by Anselm Mak, Nien Yee Kow

“…Lastly, while currently available outcomes of clinical trials evaluating therapeutic agents which manipulate the T cells such as calcineurin inhibitors indicate that they are at least as efficacious and safe as conventional immunosuppressants in treating lupus glomerulonephritis, larger clinical trials are undoubtedly required to validate these as-yet favourable findings.…”
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Bioactive Ingredients in Traditional Fermented Food Condiments: Emerging Products for Prevention and Treatment of Obesity and Type 2 Diabetes by Alphonse Laya, Honoré Wangso, Iva Fernandes, Raphaël Djakba, Joana Oliveira, Eugenia Carvalho

“…Because of the potential therapeutic significance of bioactive ingredients, the consumption of TFC could be recommended as a functional condiment. …”
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Current Status of Gout Arthritis: Current Approaches to Gout Arthritis Treatment: Nanoparticles Delivery Systems Approach by Yedi Herdiana, Yoga Windhu Wardhana, Insan Sunan Kurniawansyah, Dolih Gozali, Nasrul Wathoni, Ferry Ferdiansyah Sofian

“…Nanoparticle drug delivery enhances biological availability and delivery to targets, which may increase therapeutic efficacy and decrease general toxicity. …”
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Comparative phytochemical and pharmacological analysis of two cultivars of Annona squamosa L. cultivated in Egypt by Safaa Yassin, Samah M. Elsohafy, Amr El-Hawiet, Maged S. Abdel-Kader, Doaa A. Ghareeb, Fikria A. Darwish, Masouda E. Amer

“…Overall, our findings indicate the potential for using active compounds of Annona squamosa L. cultivars to develop new therapeutic agents for cancer therapy and immune enhancement.…”
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Plant-Derived Anti-Inflammatory Compounds: Hopes and Disappointments regarding the Translation of Preclinical Knowledge into Clinical Progress by Robert Fürst, Ilse Zündorf

“…Human trials of good quality are often missing or, when available, are frequently not suitable to really prove a therapeutical value. This minireview will summarize the current situation of 6 very prominent plant-derived anti-inflammatory compounds: curcumin, colchicine, resveratrol, capsaicin, epigallocatechin-3-gallate (EGCG), and quercetin. …”
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