Inspiratory Capacity during Exercise: Measurement, Analysis, and Interpretation by Jordan A. Guenette, Roberto C. Chin, Julia M. Cory, Katherine A. Webb, Denis E. O'Donnell

“…We will also briefly discuss IC responses to exercise in health and disease and will consider how various therapeutic interventions influence the IC, particularly in patients with chronic obstructive pulmonary disease. …”
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NOD Dendritic Cells Stimulated with Lactobacilli Preferentially Produce IL-10 versus IL-12 and Decrease Diabetes Incidence by Jean N. Manirarora, Sarah A. Parnell, Yoon-Hyeon Hu, Michele M. Kosiewicz, Pascale Alard

“…Evaluation of the relative production of IL-10 and IL-12 by DCs may be a very useful means of identifying agents that have therapeutic potential.…”
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Impact of hyper- and hypothermia on cellular and whole-body physiology by Toshiaki Iba, Yutaka Kondo, Cheryl L. Maier, Julie Helms, Ricard Ferrer, Jerrold H. Levy

“…Converse to hyperthermia, hypothermia is generally protective, as seen in therapeutic hypothermia. However, accidental hypothermia presents another environmental threat due to arrhythmias, cardiac arrest, and coagulopathy. …”
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Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy by Jia Liu, Yunqi Zhang, Xiaoyu Xu, Xi Dong, Yunfeng Pan, Xiaobo Sun, Yun Luo

“…Diabetic retinopathy (DR) is a blinding complication of microangiopathy. First-line therapeutic drugs are all focused on late-stage DR and have several side effects, which could not meet clinical needs. …”
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Enterococcus faecium HDRsEf1 Protects the Intestinal Epithelium and Attenuates ETEC-Induced IL-8 Secretion in Enterocytes by Zhongyuan Tian, Xiaofang Liu, Ran Dai, Yuncai Xiao, Xiliang Wang, Dingren Bi, Deshi Shi

“…These results may contribute to the development of therapeutic interventions using Ef1 in intestinal disorders of piglets.…”
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Case of Primary Breast and Ipsilateral Axillary T-Cell Lymphoma: a Rare Occurrence by Faryal Afridi, Garry D. Ruben, Eric Oristian

“…It is imperative that the surgeon is aware of this rare diagnosis to facilitate appropriate therapeutic intervention.…”
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Pituranthos chloranthus Oil as an Antioxidant-Based Adjuvant Therapy against Cisplatin-Induced Nephrotoxicity by Aida Lahmar, Zaineb Dhaouefi, Rihab Khlifi, Fairouz Sioud, Leila Chekir- Ghedira

“…The therapeutic outcome of cisplatin is limited due to its adverse side effects in normal tissues. …”
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Potential Nephroprotective Effect of Kaempferol: Biosynthesis, Mechanisms of Action, and Clinical Prospects by Maulana Yusuf Alkandahri, Asman Sadino, Barolym Tri Pamungkas, Zulpakor Oktoba, Maya Arfania, Nia Yuniarsih, Eko Sri Wahyuningsih, Yuliani Dewi, Sri Ayu Winarti, Sri Tantia Dinita

“…Natural drugs are currently being explored as a new therapeutic strategy for managing kidney diseases. Kaempferol, a polyphenol found in plants, including vegetables, legumes, and fruits, has been extensively studied in various nephrotoxicity protocols. …”
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The Role of the IL-12 Cytokine Family in Directing T-Cell Responses in Oral Candidosis by Xiao-Qing Wei, Helen Rogers, Michael A. O. Lewis, David W. Williams

“…Understanding the detailed mechanisms that underlie host immunity to Candida not only will be of benefit in terms of the infections caused by this organism but could also be exploited in the development of therapeutic interventions for other diseases.…”
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Antihepatitis B Virus Activity of a Protein-Enriched Fraction from Housefly (Musca domestica) in a Stable HBV-Producing Cell Line by Xuemei Lu, Xiaobao Jin, Jie Wang, Fujiang Chu, Jiayong Zhu

“…Although several vaccines and therapeutic strategies are currently being implemented to combat HBV virus, effective antiviral therapy against HBV infection has not been fully developed. …”
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Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer by Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng, Yue Chen, Yue Chen, Jing Wang, Jing Wang, Miao He, Miao He, Junyao Qiu, Yun Huang

“…This review comprehensively summarizes the relationship between autophagy and oral cancer, focusing on its mechanisms and therapeutic potential when combined with conventional treatments. …”
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NET formation-mediated in situ protein delivery to the inflamed central nervous system by Yina Wu, Jinwon Park, Quoc-Viet Le, Junho Byun, Jaehyun Choi, Enzhen Xu, Jaiwoo Lee, Yu-Kyoung Oh

“…Here we show that neutrophils, which naturally migrate through these barriers to inflamed CNS sites and release neutrophil extracellular traps (NETs), can be leveraged for therapeutic delivery. Tannic acid nanoparticles tethered with anti-Ly6G antibody and interferon-β (aLy6G-IFNβ@TLP) are constructed for targeted neutrophil delivery. …”
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A case of emergency stent graft placement for subclavian artery injury during ventriculoperitoneal shunt placement by Minoru Dote, MD, Shingo Hamaguchi, MD, Shoko Arizono, MD, Songhyon Cho, MD, Shinji Wada, MD, Shintaro Nawata, MD, Kazuki Hashimoto, MD, Hidefumi Mimura, MD

“…With advancements in medical devices and imaging techniques, endovascular treatment using stent grafts has emerged as a viable and aggressive therapeutic option for traumatic subclavian artery injuries, including iatrogenic cases. …”
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Discovery of thymol-fused chalcones as new competitive \(\alpha\)-glucosidase inhibitors: Design, synthesis, biological evaluation, and molecular modeling studies by Ade Danova, Elvira Hermawati, Warinthorn Chavasiri, Didin Mujahidin, Anita Alni, Robby Roswanda

“…This research contributes significantly to the understanding of thymol-fused chalcones that may have therapeutic potential and their possible application in the treatment of type 2 diabetes mellitus (T2DM) for further study.…”
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Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer by Renee Vermeij, Toos Daemen, Geertruida H. de Bock, Pauline de Graeff, Ninke Leffers, Annechien Lambeck, Klaske A. ten Hoor, Harry Hollema, Ate G. J. van der Zee, Hans W. Nijman

“…These results indicate that a multiepitope vaccine, comprising these antigens, could serve as a universal therapeutic vaccine for the vast majority of ovarian cancer patients.…”
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Retrovirus Entry by Endocytosis and Cathepsin Proteases by Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto

“…Understanding the entry mechanism of retroviruses contributes to developments of novel therapeutic approaches against retrovirus-induced diseases and efficient exploitation of retroviral vectors. …”
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Nano-Oncologic Vaccine for Boosting Cancer Immunotherapy: The Horizons in Cancer Treatment by Chao Chen, Yue Xu, Hui Meng, Hongyi Bao, Yong Hu, Chunjian Li, Donglin Xia

“…Overall, nano-oncologic vaccines hold great promise for changing the landscape of cancer treatment and advancing personalized medicine, paving the way for more effective therapeutic strategies tailored to individual patient needs.…”
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Integrated multi-omics profiling reveals neutrophil extracellular traps potentiate Aortic dissection progression by Yu-Fei Zhao, Zi-Ang Zuo, Zhe-Yun Li, Ye Yuan, Shi-Chai Hong, Wei-Guo Fu, Bin Zhou, Li-Xin Wang

“…It is imperative to delve into the exploration of prognostic indicators to streamline the identification of individuals at elevated risk for postoperative AAEs, and therapeutic targets to optimize the efficacy of TEVAR for patients with AD. …”
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Expression profiles of miR-101-3p and miR-431-5p as potential diagnostic biomarkers for rheumatoid arthritis by Mohamed M. Sadaty, Salma M. Mekhemer, Shaimaa Abdel-Ghany, Amira R. El-Ansary, Rana Mohamed, Nashaat N. Kamal, Hussein Sabit

“…Further research is warranted to elucidate the precise mechanisms underlying miRNA involvement in RA and to explore their potential as therapeutic targets.…”
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Beneficial microbiome and diet interplay in early-onset colorectal cancer by Zhengyuan Zhou, Linda Kleis, Ana Depetris-Chauvin, Stefanie Jaskulski, Victoria Damerell, Karin B Michels, Biljana Gigic, Ute Nöthlings, Gianni Panagiotou

“…All together, we outline the current research landscape in this area and propose directions for future investigations that could pave the way for novel preventive and therapeutic strategies.…”
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