Effect of Early Bedside Occupational Therapy Combined with Routine Rehabilitation on Reconstitution of Bed-chair Transfer in Acute Stroke Patients by Dengyao LI, Lun LUO, Tao XIANG, Xiaoyun WANG, Zejin LONG

“…Bed-chair transfer function of two groups before and after treatment was evaluated by the modified Barthel index (MBI), Berg balance scale (BBS), balance subscale of the Fugl-Meyer (FIM) and rivermead mobility index (RMI).Results:After two weeks, the MBI transfer function score, BBS score, FIM score and RMI score in the two groups were increased significantly than before treatment (<italic>P</italic>&lt;0.05), and more increase was observed in experimental group than those in control group (<italic>P</italic>&lt;0.05).Conclusion:Conventional rehabilitation therapy can facilitate the reconstruction of bed-chair transfer function in patients with acute stroke, and conventional rehabilitation therapy combined with bedside occupational therapy has better therapeutic effect on the disease.…”
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Rehabilitation with Poststroke Motor Recovery: A Review with a Focus on Neural Plasticity by Naoyuki Takeuchi, Shin-Ichi Izumi

“…Here, we review novel stroke rehabilitation techniques associated with neural plasticity and discuss individualized strategies to identify appropriate therapeutic goals, prevent maladaptive plasticity, and maximize functional gain in patients with stroke.…”
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Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature by Angus Nnamdi Oli, Samson Adedeji Adejumo, Adekunle Babajide Rowaiye, Joyce Oloaigbe Ogidigo, Jarrad Hampton-Marcell, Gordon C. Ibeanu

“…We also explore the latest advancements in combination therapies, which synergistically integrate multiple immunotherapeutic strategies to overcome resistance and enhance therapeutic outcomes. This review offers key insights into the future of cancer immunotherapy with a focus on advancing more effective and personalized treatment strategies.…”
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Human milk oligosaccharides: bridging the gap in intestinal microbiota between mothers and infants by Wen Sun, Lin Tao, Chen Qian, Pei-pei Xue, Si-si Du, Ying-na Tao

“…HMOs can enhance intestinal mucosal barrier function and affect the intestinal function of the host through immune function, which has a therapeutic effect on specific infant intestinal diseases, such as necrotizing enterocolitis. …”
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Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection. by Fan Bu, Gang Ye, Kimberly Morsheimer, Alise Mendoza, Hailey Turner-Hubbard, Morgan Herbst, Benjamin Spiller, Brian E Wadzinski, Brett Eaton, Manu Anantpadma, Ge Yang, Bin Liu, Robert Davey, Fang Li

“…Nanobodies, a type of single-domain antibody, have demonstrated promising therapeutic potential. We identified two anti-EBOV nanobodies, Nanosota-EB1 and Nanosota-EB2, which specifically target the EBOV glycoprotein (GP). …”
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Diabetes mellitus: The pathophysiology as a canvas for management elucidation and strategies by Franklyn Nonso Iheagwam, Olawumi Toyin Iheagwam

“…These findings could lay the groundwork for inventive therapeutic strategies and leads from natural products based on the proper elucidation of antidiabetic mechanisms, thereby improving management and the impact of DM.…”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…Despite the new advances in cancer therapies, there is still a continuous need for safe and effective therapeutic agents. Cysteamine is an aminothiol endogenously synthetized by human cells during the degradation of coenzyme-A. …”
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Colitis in spondyloarthritis by Muhammed Hafis, Vikas Agarwal

“…Fecal calprotectin is emerging as a noninvasive screening tool for detecting clinically silent IBD in patient with SpA. Several therapeutic targets have emerged in the last few years based on the understanding of the pathogenic mechanism and have considerably changed the management of both IBD and SpA.…”
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Glioblastoma Multiforme Stem Cells by Irena Dimov, Deasanka Tasic-Dimov, Irena Conic, Vladisav Stefanovic

“…This review presents a summary of the present knowledge both on GBMSCs and the GBM, and/or GBMSC-related mechanisms of developing both local and systemic immunosuppression, of which an understanding may lead to the development of the novel and effective therapeutic strategies.…”
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Endoscopic Closure for EUS and ERCP Related Duodenal Perforation by Endoclips by Yaping Liu, Dong Wang, Zhaoshen Li

“…To investigate the therapeutic safety, feasibility, and efficacy of endoclips for closing the endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) related duodenal perforation in a retrospective study from a single center. …”
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Streptomyces at the Heart of Several Sectors to Support Practical and Sustainable Applications: A Review by Oumaima Beroigui, Faouzi Errachidi

“…In the medical and therapeutic sectors, this paper emphasizes the potential of actinobacteria, in particular Streptomyces species, in the production of antibiotics, antioxidant, and anticancer agents, opening up avenues for the creation of molecules with high benefits. …”
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Analyzing Morphometry of Foramen Magnum using CBCT: A Forensic Radiology Study by Deepankar Misra, Sumit Bateja

“…The crucial tissues that travel via the foramen magnum make its proportions extremely important from a therapeutic standpoint. Objectives: The study’s objective was to do morphometric analysis of foramen magnum and to obtain any gender-wise or age-wise correlation between these measurements of foramen magnum in population of Western Uttar Pradesh using cone beam computed tomography (CBCT). …”
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miR-1247-3p regulation of CCND1 affects chemoresistance in colorectal cancer. by Dequan Wang, Jielian Wang, Fei Yao, Zhufu Xie, Jianze Wu, Huiguang Chen, Qingming Wu

“…These results highlight the pivotal role of miR-1247-3p in reducing chemotherapy resistance through the inhibition of CCND1, providing insight into a promising therapeutic strategy for overcoming CRC resistance.…”
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Successful Treatment of Pediatric Generalized Pustular Psoriasis with Secukinumab by Yu K, Bao H, Wu X

“…Our case report indicates that IL-17A inhibition as a promising therapeutic option for pediatric GPP without combination with other systemic agents.Keywords: juvenile pustular psoriasis, biologics, interleukin 17, secukinumab…”
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Long Noncoding RNA Regulation of Pluripotency by Alessandro Rosa, Monica Ballarino

“…As such, human Embryonic Stem Cells (hESCs) and human induced Pluripotent Stem Cells (hiPSCs) provide a unique opportunity for studying the earliest steps of human embryogenesis and, at the same time, are of great therapeutic interest. The molecular mechanisms underlying pluripotency represent a major field of research. …”
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Annexin V Imaging Detects Diabetes-Accelerated Apoptosis and Monitors the Efficacy of Benfotiamine Treatment in Ischemic Limbs of Mice by Kyung-Ho Jung, Jin Hee Lee, Jin Won Park, Jin Young Paik, Cung Hoa Thien Quach, Eun Jeong Lee, Kyung-Han Lee

“…Thus, AnxV imaging may be useful for monitoring the efficacy of therapeutic agents designed to suppress ischemia-induced apoptosis.…”
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Cross-Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity by Jin Bu, Zhaohui Wang

“…The purpose of the current review is to highlight the complex interplay between the microbiota and CVD via TMAO and different immune cells and discuss the roles of probiotics and nutrition interventions in modulating the intestinal microbiota as novel therapeutic targets of CVD.…”
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Navigating the Evolving Treatment Paradigm for _EGFR_-Mutant NSCLC by Sebastian Kraus

“…The high prevalence of these _EGFR_ mutations in NSCLC has led to significant research efforts aimed at optimizing therapeutic options for patients. This review article highlights the key findings from recent studies in the field of _EGFR_ mutations in NSCLC. …”
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Cytokines and Myelination in the Central Nervous System by Thomas Schmitz, Li-Jin Chew

“…Experimental models that mimic human disease have been developed in order to study pathogenic and therapeutic mechanisms, but have shown mixed success in clinical application. …”
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Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity by Appalaraju Jaggupilli, Eyad Elkord

“…Cancer stem cell population is a subset of cells capable of dictating invasion, metastasis, heterogeneity, and therapeutic resistance in tumours. Eradication of this rare population is a new insight in cancer treatment. …”
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