Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics by John Burke, Ravindra Kolhe, Monte Hunter, Carlos Isales, Mark Hamrick, Sadanand Fulzele

“…Specifically, stem cell-derived exosomes have demonstrated great ability to provide therapeutical benefits. Exosomal products can include miRNA, other genetic products, proteins, and various factors. …”
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Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation by Giuseppe Vassalli

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Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats by Fred Kim, Padmanabh Singh, Hyunji Jo, Tianyang Xi, Dong-Keun Song, Sae Kwang Ku, Jai Jun Choung

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<i>Klebsiella pneumoniae</i> Phage M198 and Its Therapeutic Potential by Lika Leshkasheli, Ia Kusradze, Darejan Bolkvadze, Lia Askilashvili, Maria Chichashvili, Giorgi Tsertsvadze, Elisabed Zaldastanishvili

“…This prospect highlights the need for well-characterized therapeutic phages. In this work, we describe a <i>K. pneumoniae</i> phage, which also infects strains of <i>Klebsiella oxytoca</i>. …”
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Management of Oro-Antral Communication: A Systemic Review of Diagnostic and Therapeutic Strategies by Gianna Dipalma, Angelo Michele Inchingolo, Irma Trilli, Laura Ferrante, Angela Di Noia, Elisabetta de Ruvo, Francesco Inchingolo, Antonio Mancini, Stefan Cocis, Andrea Palermo, Alessio Danilo Inchingolo

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Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy by Naths Grazia Sukubo, Paolo Bigini, Annalisa Morelli

“…In this review, we will explore the dual role of macrophages in NC delivery, highlighting their physiological functions, the challenges posed by the mononuclear phagocyte system, and innovative strategies to exploit macrophage interactions for therapeutic advantage. Recent advancements in treating liver and lung diseases, particularly focusing on macrophage polarization and RNA-based therapies, have highlighted the potential developments in macrophage–NC interaction. …”
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Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

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Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies by Samuel Oluwadare Olalekan, Olalekan Olanrewaju Bakare, Patrick Godwin Okwute, Ifabunmi Oduyemi Osonuga, Muinat Moronke Adeyanju, Victoria Biola Edema

“…The review also explored the impact of targeted therapeutic approaches aimed at modulating these proteins to improve patient outcomes. …”
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Cancer therapy through the engineering of exosomes for the delivery of therapeutic cargo: Mechanisms and applications by Jeeva Jothi Kumaravel, Geetha Anbalagan, Muthamizh Selvamani, Dilipan Elangovan, Balachandran Subramanian

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Desmoplastic reaction in the microenvironment of head and neck and other solid tumors: the therapeutic barrier by Kohei Okuyama, Maiko Tsuchiya, Kala Chand Debnath, Shajedul Islam, Souichi Yanamoto

“…Therapeutic Advances in Medical Oncology…”
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Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications by Sijia He, Ziying Xu, Xianlin Han

“…Finally, we assessed the progresses and obstacles in lipid-based therapeutics and proposed potential strategies for leveraging lipidomics in the treatment of AD.…”
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Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders by Heechul Jun, Syed Mohammed Qasim Hussaini, Michael J. Rigby, Mi-Hyeon Jang

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Clinical, Epidemiological and Therapeutic Characteristics of Patients Admitted for a Bronchial Asthma Attack by Juan Carlos Yanes Macías, Juan Camilo Díaz Ceballos, Mercedes Fonseca Hernández, Ileana García Rodríguez, Caridad Llul Tombo, Daimy Tio González

“…<br /><strong>Objective:</strong> to describe the clinical, epidemiological and therapeutic characteristics of bronchial asthma crises at the Paquito González Cueto University Pediatric Hospital in Cienfuegos, during 2015 and 2016. …”
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Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis by Xiaoming Li, Xiaoming Li, Rui Xu, Rui Xu, Dan Zhang, Ji Cai, Ji Cai, He Zhou, He Zhou, Tao Song, Tao Song, Xianyao Wang, Xianyao Wang, Qinghong Kong, Liujin Li, Zhaohui Liu, Zhixu He, Zhengzhen Tang, Jun Tan, Jidong Zhang, Jidong Zhang, Jidong Zhang

“…This review aims to summarize Baicalin’s progress in these areas, including its molecular mechanism, application in treatment, and absorption, distribution, metabolism, and excretion. Baicalin’s therapeutic effects are achieved through various pathways, including antioxidant, anti-inflammatory, antifibrosis, and regulation of apoptosis and cell proliferation. …”
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Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm by Ka Zhang, Yuan Liu, Aiqin Mao, Changzhu Li, Li Geng, Hao Kan

“…Background The proteome is a key source of therapeutic targets. We conducted a comprehensive Mendelian randomization analysis across the proteome to identify potential protein markers and therapeutic targets for abdominal aortic aneurysm (AAA). …”
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Multifunctional Synthetic Poly(-Glutamic Acid)–Based Cancer Therapeutic and Imaging Agents by Marites P. Melancon, Chun Li

“…Synthetic biocompatible polymers have been used to improve the efficacy of both small-molecular-weight therapeutics and imaging agents. Furthermore, multiple targeted anticancer agents and/or imaging reporters can be attached to a single polymer chain, allowing multifunctional and/or multimodality therapy and molecular imaging. …”
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Author Correction: Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells by Marta Buzzetti, Sonia Morlando, Dimitrios Solomos, Ammara Mehmood, Alexander W. I. Cox, Mattia Chiesa, Yuri D’Alessandra, Michela Garofalo, Caroline H. Topham, Gianpiero Di Leva

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Infarct volume as a predictor and therapeutic target in post-stroke cognitive impairment by Lingjia Xu, Dan Shan, Danling Wu

“…Nevertheless, significant gaps persist in our understanding of its pathophysiological mechanisms and potential therapeutic targets, which warrants further research. …”
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Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances by Mithila Debnath, Mahir Azmal, Rashid Taqui, Moshiul Alam Mishu, Ajit Ghosh

“…Purpose: The study aimed to adopt a new strategy to identify and characterize potential biomarkers and therapeutic phytochemicals for AD by integrating gene expression data and computational analysis. …”
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Therapeutic Effect of Gypenosides on Antioxidant Stress Injury in Orbital Fibroblasts of Graves’ Orbitopathy by Chao Ma, Haoyu Li, Wei Liu, Shuwen Lu, Xian Li, Jinyuan Chen, Kaijun Li, Wenzhan Wang

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