Overview of hepatocarcinogenesis focusing on cellular origins of liver cancer stem cells: a narrative review by Jong Ryeol Eun

“…Therefore, to effectively treat HCC, developing therapeutic strategies that target liver CSCs is essential. …”
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Quantitative structure property relationship study of postpartum depression medications using topological indices and regression models by Gayathri K. B, S. Roy

“…Additionally, this research advances our knowledge of the molecular basis of PPD treatment and could help develop more focused and efficient therapeutic approaches. The legitimacy of the recently authorized medication Zurzuvae, which treats postpartum depression, is also verified here.…”
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Evaluation of the Effects of Multifocal Intraocular Lens Oculentis LENTIS Mplus LS-313 MF30 on Visual Performance in Patients Affected by Bilateral Cataract and Treated with Phacoe... by R. Nuzzi, F. Tripoli, A. Ghilardi

“…In accordance with the literature, the Oculentis LENTIS Mplus MF30 has proved to be a valid therapeutic alternative for visual rehabilitation after phacoemulsification of the cataract in patients also wishing to treat presbyopia, at the cost of very few visual adverse effects. …”
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Practical Vessel Imaging by Computed Tomography in Live Transgenic Mouse Models for Human Tumors by Gordon L. Kindlmann, David M. Weinstein, Greg M. Jones, Christopher R. Johnson, Mario R. Capecchi, Charles Keller

“…Contrast-enhanced small-animal computed tomography is an economical and highly quantitative tool for serially examining tumor development in situ, for analyzing the network of blood vessels that nourish them, and for following the response of tumors to preclinical therapeutic intervention(s). We present practical considerations for visualizing the vascular network of transgenic mouse tumors. …”
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"Energetics of the outer retina II: Calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of cellular process... by Christina Kiel, Stella Prins, Alexander J E Foss, Philip J Luthert

“…Our data provide insights into vulnerabilities in the aging OR and suggest that diurnal constraints may be important when considering therapeutic interventions to optimize metabolism.…”
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αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson’s Disease? by David Protter, Charmaine Lang, Antony A. Cooper

“…Neither a cure nor effective long-term therapy exist and the lack of knowledge of the molecular mechanisms responsible for PD development is a major impediment to therapeutic advances. The protein αSynuclein is a central component in PD pathogenesis yet its cellular targets and mechanism of toxicity remains unknown. …”
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An Angiotensin-converting Enzyme Inhibition Activity by Various Natural Approaches: A Statistic Review by Rupal K. Chhaniyara, Dhara A. Gamit

“…Among all the classes of antihypertensive drugs, angiotensin-converting enzyme (ACE) inhibition has been considered an effective therapeutic approach for the management of hypertension. …”
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Progress of the Target Selection and Localization of Repetitive Transcranial Magnetic Stimulation to Improve Upper Limb Function after Stroke by LIU Canhuan, SHEN Ying, DAI Wenjun, GUO Chuan, CHENG Yihui, ZHU Yi, WANG Tong

“…Currently, rehabilitation techniques for improving post-stroke upper limb motor function, both domestically and internationally, primarily involve motor function training.Repetitive transcranial magnetic stimulation (rTMS), because it can enhance upper limb motor function recovery by modulating cortical excitability and promoting neuroplasticity, has been increasingly used in stroke rehabilitation and has been included in the guideline as a grade A recommendation.However, there is still large heterogeneity in the relevant clinical studies, and the therapeutic effect is affected by factors such as different target selection and target localization accuracy. …”
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Uncomplicated Amyand’s hernia in a setting of abdominal wall insufficiency: a case report by Vasishtha Avadhani Upadrasta, Avinash Koul, Vikrant Singh Chauhan

“…Abstract Introduction Amyand’s hernia, an uncommon condition characterized by the presence of the appendix within an inguinal hernial sac (< 1% incidence), poses diagnostic and therapeutic challenges. Often it is an intraoperative finding, with almost no clinical symptoms. …”
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Computer Aided Diagnostic System for Blood Cells in Smear Images Using Texture Features and Supervised Machine Learning by Shakhawan Hares Wady

“…Identification and diagnosis of leukemia earlier is a contentious issue in therapeutic diagnostics for reducing the rate of death among people with Acute Lymphoblastic Leukemia (ALL). …”
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Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus by Ranadheer R. Dande, Vasil Peev, Mehmet M. Altintas, Jochen Reiser

“…However, the search for novel therapeutic strategies is ongoing. These include seeking specific molecules that contribute to the development and progression of DN to potentially interfere with these “molecular targets” as well as with the cellular targets within the kidney such as podocytes, which play a major role in the pathogenesis of DN. …”
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Gene Therapy: A step toward advanced orthodontics – A narrative review by Monika Shukla, Shalu Jain, C. Munish Reddy, Pradeep Raghav, Kumar Amit, Rinchin Yangzom, Shivika Garg, Aastha Kamrani

“…Background: Gene therapy deals with the insertion of exogenous genes into a cell to produce the desired therapeutic effect. After the introduction of gene therapy in dentistry, this field is also flourishing rapidly in the branch of orthodontics and dentofacial orthopedics as it can prevent many prenatal and postnatal dentofacial anomalies which have the genetical etiology. …”
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MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives by Hans Carl Hasselbalch, Mads Emil Bjørn

“…The consequences of this model are discussed, including the increased risk of second cancers and other inflammation-mediated diseases, emphasizing the urgent need for rethinking our therapeutic approach. Early intervention with interferon-alpha2, which as monotherapy has been shown to be able to induce minimal residual disease, in combination with potent anti-inflammatory agents such as JAK-inhibitors is foreseen as the most promising new treatment modality in the years to come.…”
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A Comprehensive Analysis of Fibromyalgia and the Role of the Endogenous Opioid System by Mario García-Domínguez

“…This complexity arises from the notion that an improved understanding could contribute to the development of innovative therapeutic strategies aimed at targeting the endogenous opioid system in the context of fibromyalgia. …”
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Hemoglobin: A Nitric-Oxide Dioxygenase by Paul R. Gardner

“…NOD inhibitors are being pursued for therapeutic applications as antibiotics and antitumor agents. …”
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GABAergic Neuronal Precursor Grafting: Implications in Brain Regeneration and Plasticity by Manuel Alvarez Dolado, Vania Broccoli

“…These results cast new light on dynamics and plasticity of adult neuronal assemblies and their associated functions disclosing new therapeutic opportunities for the near future.…”
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Behavioral Activation (BA) in the Management of Depression in an Adolescent with Down Syndrome in Dubai by Sidra Shadan, Sarah Almarzooqi, Meshal A. Sultan

“…In this report, we discuss BA further as a potentially effective therapeutic approach to the treatment of depressive symptoms in children and adolescents with DS and intellectual disabilities.…”
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Choosing the Right Angiotensin Converting Enzyme Inhibitors; Gender –Specific Approach by Neena Elsa Varghese, K. Jegaveerapandi, Goutham Yerrakula

“…By embracing a personalized medicine framework that accounts for gender-related differences, health-care professionals can optimize therapeutic interventions, minimize treatment disparities, and strive for improved cardiovascular health outcomes for all individuals. …”
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MiRNAs as major players in brain health and disease: current knowledge and future perspectives by Sarika V. Kapplingattu, Sujata Bhattacharya, Yogita K. Adlakha

“…We highlight the promising therapeutic potential of miRNAs as antitumor agents for aggressive human brain tumors including glioblastoma.…”
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Antimicrobial Activity of <i>Zingiber Officinale</i> and <i>Allium Sativum</i> on some Drug Resistant Bacterial Isolates by S.E. Emmanuel, E.O. Ehinmitan, R.S. Bodunde, J.C. Joseph

“… Ginger and garlic are very important and useful spices and are used as therapeutic agent against many pathological infections. …”
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