Rise in arsenic pollution and oral cancer: A call for action by Amol S. Dhane, Sachin C. Sarode, Gargi S. Sarode, Nilesh Kumar Sharma

“…We also discussed the therapeutic potential of arsenic in oral cancer. Future research is proposed to investigate the molecular role of arsenic in gutkha and tobacco users, considering its contribution to oral cancer heterogeneity.…”
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Automated music therapy for anxiety and depression management in older people (AMITY) by Faizan Malik, White P.J., Dey Indrakshi

“…It reduces the reliance on mental health professionals while providing tailored therapeutic interventions, thereby contributing to improved mental well-being and addressing the gap in mental health care services for the elderly population.…”
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Amniotic Fluid Stem Cells: Future Perspectives by Margit Rosner, Katharina Schipany, Bharanidharan Shanmugasundaram, Gert Lubec, Markus Hengstschläger

“…Many different groups have demonstrated that AFS cells can be differentiated into all three germ layer lineages, what is of relevance for both, the scientific and therapeutical usage of these cells. Of special importance for the latter is the fact that AFS cells are less tumorigenic than other pluripotent stem cell types. …”
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Peptide hydrogel-drug conjugates for tailored disease treatmentGuidelines to assemble peptide-based hydrogel-drug conjugates, referenced with a selection of relevant publications. by Thibault Cauwenbergh, Steven Ballet, Charlotte Martin

“…Efficacy of therapeutic drugs is oftentimes limited in time by their low metabolic stability and rapid clearance mechanisms. …”
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Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants by Michelle R. Garnsey, Yang Wang, David J. Edmonds, Matthew F. Sammons, Benjamin Reidich, Youngwook Ahn, Yotam Ashkenazi, Anthony Carlo, Matthew A. Cerny, Karen J. Coffman, Jeffrey A. Culver, Anne-Marie Dechert Schmitt, Heather Eng, Ethan L. Fisher, Jemy A. Gutierrez, Larry James, Samantha Jordan, Jeffrey T. Kohrt, Melissa Kramer, Erik A. LaChapelle, Jack C. Lee, Jisun Lee, Dongmei Li, Zhenhong Li, Shenping Liu, Jianhua Liu, Thomas V. Magee, Melissa R. Miller, Michael Moran, Deane M. Nason, Nicole L. Nedoma, Steven V. O’Neil, Mary A. Piotrowski, Jillian Racich, Ruth F. Sommese, Lucy M. Stevens, Ann S. Wright, Jun Xiao, Liying Zhang, Dahui Zhou, Ornella Barrandon, Michelle F. Clasquin

“…Abstract Several hydroxysteroid dehydrogenase 17-beta 13 variants have previously been identified as protective against metabolic dysfunction-associated steatohepatitis (MASH) fibrosis, ballooning and inflammation, and as such this target holds significant therapeutic potential. However, over 5 years later, the function of 17B-HSD13 remains unknown. …”
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A molecular toolkit for heterologous protein secretion across Bacteroides species by Yu-Hsuan Yeh, Vince W. Kelly, Rahman Rahman Pour, Shannon J. Sirk

“…This toolkit promises to enable expanded development of long-term living therapeutic interventions for chronic gastrointestinal disease.…”
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Ilex paraguariensis extract as an alternative to pain medications by Nowacki Luciana C., Stechman-Neto José, Schiefer Elberth M., Santos Andressa F., Stinghen Andréa E. M., Sassaki Guilherme L., De Souza Lauro M., Cristoff Killian E., De Souza Wesley M.

“…Notably, the administration of multiple doses of Ilex paraguariensis extract was considered safe from the therapeutic point of view.…”
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Water pollution, cholera, and the role of probiotics: a comprehensive review in relation to public health in Bangladesh by Md. Rayhan Chowdhury, Ariful Islam, Valentina Yurina, Takeshi Shimosato, Takeshi Shimosato, Takeshi Shimosato

“…This review aims to shed light on the potential of probiotics in revolutionizing cholera management and to offer insights into their application as both preventive and therapeutic tools in the fight against this enduring public health challenge.…”
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Beneath the surface: unveiling the gut–brain axis in anorexia and depression by Fatima Shahid, Zain Afridi, Muhammad Ali, Muhammad Nabeel Saddique, Javed Iqbal, Anurag Jha

“…These include large-scale, multi-center studies to quantify microbiota profiles, mechanistic understanding of gut microbiota alterations, and diagnostic and therapeutic advances using microbiota as biomarkers. …”
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Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus by Md. Sakib Hossen, Siew Hua Gan, Md. Ibrahim Khalil

“…Since diabetes mellitus (DM) is one of the most common and serious endocrine metabolic disorders, it is important to elucidate novel antidiabetic therapeutic agents from various sources, including natural products. …”
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WAC Facilitates Mitophagy‐mediated MSC Osteogenesis and New Bone Formation via Protecting PINK1 from Ubiquitination‐Dependent Degradation by Shuai Fan, Jinteng Li, Guan Zheng, Ziyue Ma, Xiaoshuai Peng, Zhongyu Xie, Wenjie Liu, Wenhui Yu, Jiajie Lin, Zepeng Su, Peitao Xu, Peng Wang, Yanfeng Wu, Huiyong Shen, Guiwen Ye

“…The study elucidates the mechanism by which WAC modulates MSC osteogenesis, binds to PINK1 to protect it from ubiquitination, and identifies potential therapeutic targets for osteoporosis and bone defect repair.…”
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A novel lectin from mushroom Phellodon melaleucus displays hemagglutination activity, and antitumor activity in a B16 melanoma mouse model by Yuanhui Li, Peng Wang, Zejun Zhang, Qinghong Liu

“…Our findings suggest that PML is a potential anticancer therapeutic agent.…”
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Sex and gender differences in the molecular etiology of Parkinson’s disease: considerations for study design and data analysis by Samantha L. Schaffner, Kira N. Tosefsky, Amy M. Inskter, Silke Appel-Cresswell, Julia M. Schulze-Hentrich

“…Consideration of sex and gender-related factors in study design, data analysis, and interpretation have the power to expedite our knowledge of the etiology of PD in men and in women, and to inform prevention and therapeutic strategies tailored to each sex.…”
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Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro by Paulraj Kanmani, AbuZar Ansari, Julio Villena, Hojun Kim

“…These results demonstrated that immunobiotics exhibit potent immunoregulatory activity and may be used as effective therapeutic agents to alleviate inflammatory response.…”
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Modelling hepatocellular carcinoma microenvironment phenotype to evaluate drug efficacy by Sara Cherradi, Salomé Roux, Marie Dupuy, Séverine Tabone-Eglinger, Edouard Tuaillon, Marianne Ziol, Eric Assenat, Hong Tuan Duong

“…We developed a target-independent cell killing (TICK) exclusion strategy to monitor the therapeutic response. We demonstrated that our model reproduced the Barcelona Clinic Liver Cancer (BCLC) molecular classification, displayed known alterations of epigenetic players, and responded to tyrosine kinase inhibitors (TKIs) such as sorafenib, cabozantinib, and lenvatinib in a patient-dependent manner. …”
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Harnessing the Angiogenic Potential of Stem Cell-Derived Exosomes for Vascular Regeneration by F. Alcayaga-Miranda, M. Varas-Godoy, M. Khoury

“…The current gain of insight in exosomes studies highlights the power of combining cell based therapies and their secreted products in therapeutic angiogenesis.…”
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Targeting Nrf2/KEAP1 signaling pathway using bioactive compounds to combat mastitis by Muhammad Zahoor Khan, Liangliang Li, Yandong Zhan, Huang Binjiang, Xiaotong Liu, Xiyan Kou, Adnan Khan, Abdul Qadeer, Qudrat Ullah, Khalid J. Alzahrani, Tongtong Wang, Changfa Wang, Muhammad Zahoor

“…Here, we summarize recent studies to highlight the therapeutic potential of Nrf2/KEAP1 pathway in the prevention and treatment of mastitis. …”
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ANTHOCYANINS –METHODS OF EXTRACTION AND STABILIZATION by SMEREA, Olga, BULGARU, Viorica

“…Anthocyanins, natural pigments present in plants which are of interest among researchers due to their antioxidant qualities and potential therapeutic advantages in certain contexts. Their occurrence in fruits, vegetables, and blossoms attributes to their unique hues. …”
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Lingual Fibrous Hyperplasia: Case Report and Literature Review by Edison Omar Sacaquirín Zhunio, Julián Alejandro Merel Guamán, Diana Priscila Llivichuzca Inga, Kevin Adrián Quishpe Peña

“…This approach allowed precise therapeutic intervention and differential diagnosis against potentially malignant lesions such as oral leukoplakia. …”
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Advances in sodium-glucose transporter protein 2 inhibitors and tumors by Jiaqi Wang, Wenyong Yang

“…Although the clinical application of targeted therapy and immunotherapy has improved the status quo of tumor treatment, the development of new therapeutic tools for tumors is still necessary. Sodium-glucose transporter protein 2 (SGLT2) inhibitors are a new type of glycemic control drugs, which are widely used in clinical practice because of their effects on weight reduction and protection of cardiac and renal functions. …”
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