Showing 621 - 640 results of 12,750 for search '"therapeutics"', query time: 0.10s Refine Results
  1. 621
  2. 622

    Protein-bound uremic toxins as therapeutic targets for cardiovascular, kidney, and metabolic disorders by Shihan Zhang, Shasha Tang, Yalei Liu, Binghua Xue, Qinyuan Xie, Lingyun Zhao, Huijuan Yuan

    Published 2025-01-01
    “…This review explores the interactions among heart, kidney, and metabolic pathways in the context of uremic toxins and underscores the significant role of uremic toxins as potential therapeutic targets in the pathophysiology of these diseases. …”
    Get full text
    Article
  3. 623

    Gamma delta T cells in acute myeloid leukemia: biology and emerging therapeutic strategies by Venkata Lokesh Battula, Abhishek Maiti, Adishwar Rao, Akriti Agrawal, Gautam Borthakur

    Published 2024-02-01
    “…In this review, we discuss γδ T cells’ biology, roles in cancer and AML, and mechanisms of immune escape and antileukemia effect; we also discuss recent clinical advances related to γδ T cells in the field of AML therapeutics.…”
    Get full text
    Article
  4. 624
  5. 625

    Fumonisin B1 neurotoxicity: Preclinical evidence, biochemical mechanisms and therapeutic strategies by Blessing A. Obafemi, Isaac A. Adedara, Cássia Pereira Delgado, Olabisi T. Obafemi, Michael Aschner, Joao B.T. Rocha

    Published 2025-06-01
    “…This review highlights the biochemical aspects of FB1 neurotoxicity, such as its mechanisms of action as well as therapeutic strategies. Both in vitro and in vivo studies have demonstrated that alteration in sphingolipid metabolism is a major event in FB-induced neurotoxicity. …”
    Get full text
    Article
  6. 626
  7. 627
  8. 628
  9. 629

    Inflammatory Mediators and Angiogenic Factors in Choroidal Neovascularization: Pathogenetic Interactions and Therapeutic Implications by Claudio Campa, Ciro Costagliola, Carlo Incorvaia, Carl Sheridan, Francesco Semeraro, Katia De Nadai, Adolfo Sebastiani, Francesco Parmeggiani

    Published 2010-01-01
    “…As an extension of this concept, new therapeutic approaches geared to have an effect on both the vascular and the extravascular components of CNV are discussed.…”
    Get full text
    Article
  10. 630

    Comprehensive Analysis of FBXO43 Expression and Its Prognostic and Therapeutic Implications in Osteosarcoma by Jiang Jin, Kang Yao, Zhao Tingxiao, Yao Longtao, Li Yanlei, Tian Jinlong, Zhu Xiaojun, Han Liang

    Published 2025-01-01
    “…Future studies should aim to elucidate the molecular mechanisms driving FBXO43’s role and validating these findings in clinical settings to develop targeted therapeutic strategies.…”
    Get full text
    Article
  11. 631
  12. 632

    Quantifying hope: an EU perspective of rare disease therapeutic space and market dynamics by Emmanuelle Cacoub, Emmanuelle Cacoub, Nathalie Barreto Lefebvre, Dimitrije Milunov, Manish Sarkar, Soham Saha

    Published 2025-02-01
    “…The UN emphasizes improved access to primary care (diagnostic and potentially therapeutic) for these patients and their families. …”
    Get full text
    Article
  13. 633
  14. 634

    OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer by Qihui Sun, Xiaoqi Zhu, Qi Zou, Yang Chen, Tingting Wen, Tingting Jiang, Xiaojia Li, Fang Wei, Keping Xie, Jia Liu

    Published 2025-01-01
    “…Further research is warranted to explore OSBPL3 as a biomarker for predicting immunotherapy response and as a potential therapeutic target in combination with anti-PD1 therapy.…”
    Get full text
    Article
  15. 635

    Exploring Cervical Adenocarcinoma: Epidemiological Insights, Diagnostic and Therapeutic Challenges, and Pathogenetic Mechanisms by Shuhui Li, Congrong Liu, Liang Weng

    Published 2025-01-01
    “…Conclusion This review consolidates the epidemiological characteristics, diagnostic and therapeutic hurdles, and the latest advances in research on CA. …”
    Get full text
    Article
  16. 636
  17. 637
  18. 638

    Psychological Aspects of Androgen Insensitivity Syndrome: Two Cases Illustrating Therapeutical Challenges by Filippa Pritsini, Georgios A. Kanakis, Ioannis Kyrgios, Eleni P. Kotanidou, Eleni Litou, Konstantina Mouzaki, Aggeliki Kleisarchaki, Dimitrios G. Goulis, Assimina Galli-Tsinopoulou

    Published 2017-01-01
    “…The lack of standardized guidelines results in controversies regarding the proper diagnostic and therapeutic approach, including the time and type of intervention. …”
    Get full text
    Article
  19. 639

    CIMAvax-EGF®, new therapeutic alternative for lung cancer: its application in Cienfuegos by Yoana Herrera Leiva, Teresita Sabatés Llerandi

    Published 2017-04-01
    “…The overall objective of the study is to evaluate the safety and efficacy of the CIMAVAX-EGF therapeutic vaccine for the treatment of patients diagnosed with lung cancer in advanced stages of the disease and, within its specific objectives, to assess overall survival and the treated patients’ life quality.…”
    Get full text
    Article
  20. 640