Isolated Right-Sided Posttraumatic Diaphragmatic Hernia by Ibrahim Amadou Magagi, Oumarou Habou, Harissou Adamou, Ousseini Adakal, Mahamoud Omid Ali Ada, Hellé Moustapha, Habibou Abarchi

“…We report a case of right-sided posttraumatic hernia in a child following blunt trauma to highlight diagnostic difficulties and therapeutic specific aspects. A 10-year-old boy was admitted to the emergency surgical department with thoracic trauma following pedestrian accident. …”
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Pharmacokinetics of Maternal Drug Administration: Insights into Placental Transfer and Fetal Exposure by Abdullah Duhaim, Tariq Abdullah Almatroudi, Zaiad Abdullah Alghidani, Abdulsalam Saad Alhunayni, Mohamed Helmy Salama

“…Advances in pharmacokinetic research reveal dynamic alterations in drug absorption, distribution, metabolism, and excretion during pregnancy, which impact therapeutic drug levels and maternal-fetal outcomes. …”
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Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

“…These findings support the use of lysogenic phages as therapeutic Trojan Horses.…”
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Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery by Leonel Pereira, Ana Valado

“…As researchers employ advanced technologies and dive deeper into the chemical composition of seaweeds, the untapped potential of these marine organisms in drug discovery awaits further exploration and holds significant promise for future therapeutic advancements.…”
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Primary renal sarcoma in a female patient: case report by Somang Lee, Binnari Kim

“…These tumors have a very poor and aggressive prognosis, and an optimal therapeutic regimen has not yet been defined. Therefore, further studies are needed.…”
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Pain Associated with Endometriosis. A Review of Quality of Life. Psychological Aspects, Career Development, Sexual Health, and Intimate Partner Relationships by Marlena Zubiak, Martyna Byrska, Hanna Barska-Kobylińska, Sara Langner, Ewa Katarzyna Malaka, Marta Janura, Jagoda Elias, Wiktor Biesiada, Sara Szydłowska, Krzysztof Błaszków

“…Conclusions: The symptoms of endometriosis, along with limited therapeutic options, significantly affect overall quality of life, sexual health, and partner relationships. …”
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The role of complement in tumor immune tolerance and drug resistance: a double-edged sword by Ronghui Yang, Di Fu, Di Fu, Aijun Liao

“…Concurrently, the complement system can also be implicated in the emergence of drug resistance through a multitude of complex mechanisms, directly or indirectly reducing the efficacy of therapeutic interventions and facilitating the progression of cancer. …”
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Advances in Corticosteroid Therapy for Ocular Inflammation: Loteprednol Etabonate by Timothy L. Comstock, Heleen H. DeCory

“…Retrometabolic drug design has advanced the development of new corticosteroids with improved therapeutic indices. Engineered from prednisolone, loteprednol etabonate (LE) has a 17α-chloromethyl ester, in lieu of a ketone group, and a 17β-etabonate group. …”
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Combination of Fluorescence-Guided Surgery With Photodynamic Therapy for the Treatment of Cancer by Jun He MD, Leping Yang MD, Wenjun Yi MD, Wentao Fan MD, Yu Wen MD, Xiongying Miao MD, Li Xiong MD

“…Additionally, we present the combined strategy of FGS with PDT to further improve the therapeutic effect for patients with cancer. Taken together, this review provides a unique perspective and summarization of FGS.…”
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Neural correlates of facial recognition deficits in autism spectrum disorder: a comprehensive review by Jianmei Liu, Jianmei Liu, Huihui Chen, Haijing Wang, Zhidan Wang

“…Future research should emphasize longitudinal, multimodal neuroimaging approaches to better understand developmental trajectories and design personalized interventions, leveraging AI and machine learning to optimize therapeutic outcomes for individuals with ASD.…”
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Topical Nitroglycerine for Neonatal Arterial Associated Peripheral Ischemia following Cannulation: A Case Report and Comprehensive Literature Review by Rafat Mosalli, Mohamed Elbaz, Bosco Paes

“…Topical vasodilators, anticoagulation, thrombolysis, and surgery are considered secondary therapeutic strategies. A comprehensive literature search indicates that topical nitroglycerin has been utilized for the treatment of tissue ischemia in three preterms with umbilical arterial catheters and four with peripheral arterial lines. …”
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Pulmonary Alveolar Proteinosis by Sandeep M Patel, Hiroshi Sekiguchi, Jordan P Reynolds, Michael J Krowka

“…Recent advances in the understanding of the pathophysiology of PAP demonstrate that the idiopathic form is due to antigranulocyte macrophage-colony stimulating factor antibodies. Therapeutic targets that replace granulocyte macrophage colony stimulating factor or remove these antibodies are being actively developed. …”
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Dysphoric spectrum of emotional disorders at irritable bowel syndrome by M. A. Morozova, G. Ye. Rupchev, A. A. Alekseyev, A. G. Beniashvili, M. V. Mayevskaya, Ye. A. Poluektova, O. Z. Okhlobystina, V. T. Ivashkin

“…Dysphoric disorders are not regarded as independent target for therapeutic actions. Conclusion. The chronic discontent and trend to react by anger to stressful situations are traits of IBS patients, and is the basis of the development and persistance of the somatic symtpoms. …”
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Parasite in the brain: the role of Toxoplasma gondii in brain cancer and neuropsychiatric disorders by Peyman Rabiei, Mohammad Esmaeilpour-Bandboni

“…Grasping these connections is essential for creating focused therapeutic approaches and public health measures designed to reduce the impact of T. gondii infection on mental health and neuro-oncology. …”
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Pathologic complete response following low-dose radiation for advanced oral cavity cancer in a patient with human immunodeficiency virus by Amy B. Leming, Andrea L. Johnston, Greg A. Krempl, Evan J. Fowle, Daniel J. Morton, Christina E. Henson

“…Protease inhibitors in HAART can induce spontaneous tumor regression via inhibition of proteasome function and activation of apoptosis, and thus act as a cancer therapeutic. Graphical Abstract…”
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Mitochondrial DNA: A New Predictor of Diabetic Kidney Disease by Yajing Huang, Jingwei Chi, Fanxiang Wei, Yue Zhou, Yihai Cao, Yangang Wang

“…By the time, mitochondrial-targeted antioxidants will become a new method for the treatment of DKD and other diabetic complications; mtDNA also can be a therapeutic target for them.…”
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Current Concepts of Hyperinflammation in Chronic Granulomatous Disease by Nikolaus Rieber, Andreas Hector, Taco Kuijpers, Dirk Roos, Dominik Hartl

“…Here we discuss immunological mechanisms of hyperinflammation and their potential therapeutic implications in CGD.…”
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Phenotypic alterations in articulating joint cells: Role of mechanically loaded MSC secretome by Yann D. Ladner, Ursula Menzel, Keith Thompson, Angela R. Armiento, Martin J. Stoddart

“…Apart from their differentiation potential, MSCs secrete a multitude of molecules with therapeutic properties that benefit chondrogenesis and immunomodulation. …”
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Laser Photobiomodulation for a Complex Patient with Severe Hydroxyurea-Induced Oral Ulcerations by Marco Cabras, Adriana Cafaro, Alessio Gambino, Roberto Broccoletti, Ercole Romagnoli, Davide Marina, Paolo G. Arduino

“…Patients affected by polycythemia vera (PV), a myeloproliferative neoplasm characterized by an elevated red blood cell mass, are at high risk of vascular and thrombotic complications. Conventional therapeutic options aim at reducing vascular and thrombotic risk; low-dose aspirin and phlebotomy are first-line recommendations, for patients at low risk of thrombotic events, whereas cytoreductive therapy, usually hydroxyurea (HU) or interferon alpha, is recommended for high-risk patients. …”
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A Case of Nonfunctioning Pituitary Carcinoma That Responded to Temozolomide Treatment by Haruko Morokuma, Takao Ando, Takuya Hayashida, Ichiro Horie, Naoko Inoshita, Fumi Murata, Ikuko Ueki, Kan Nakamura, Misa Imaizumi, Toshiro Usa, Atsushi Kawakami

“…MGMT, an enzyme antagonized by TMZ, was negative in the tumor. The therapeutic efficacy of TMZ and dosing schedules of TMZ in pituitary carcinoma are discussed.…”
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