The use of Guyton’s approach to the control of cardiac output for clinical fluid management by Sheldon Magder

“…Accordingly, trends in RAP and cardiac output (or a surrogate of cardiac output) can provide important guides for the cause of a hemodynamic deterioration, the potential role of fluids, the limits of their use, and when the fluid is given, the response to therapeutic interventions. Use of the trends in these values provide a physiologically grounded approach to clinical fluid management.…”
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Effectiveness of Prolotherapy for Chronic Musculoskeletal Conditions by Saurabh Agarwal, Abhishek Nagaich, Nikhil Jain, Arvind Kumar Shah

“…Prolotherapy is one of the injection-based alternative therapeutic options for the treatment of chronic musculoskeletal pain. …”
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The Utilization of Diagnostic Musculoskeletal Ultrasound in the Evaluation of Gluteus Medius Tendon Pathology: A Perspective for Rehabilitation Providers by Robert C. Manske, Chris Wolfe, Phil Page, Michael L. Voight, Elizabeth Bardowski

“…For rehabilitation providers, understanding the application, strengths, and limitations of diagnostic MSKUS can enhance clinical decision-making, facilitate targeted therapeutic interventions, and potentially expedite the recovery process. …”
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Scoping review of molecular biomarkers associated with fatigue, stress, and depression in stroke survivors: A protocol. by Tarynn Potter, Nisal Gange, Eliza Whiteside, Prajwal Gyawali

“…Due to the interconnected nature of these comorbidities, it is important to improve the specificity of diagnosis and identify novel therapeutic targets to improve the quality of life for stroke survivors. …”
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« La souris ne peut pas jouer avec le chat ». Marc Christin, un écrivain à l’asile (Cery, vers 1900) by Marco Cicchini

“…The second part of the article contextualizes the writing of the book, by studying the economy of the therapeutic and affective relationship that Christin had with Dr Albert Mahaim, director of Cery, as well as the asymmetry of their power relations. …”
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Histone deacetylase inhibition with givinostat: a multi-targeted mode of action with the potential to halt the pathological cascade of Duchenne muscular dystrophy by A. Aartsma-Rus

“…HDAC inhibition has consequently been investigated as a therapeutic approach for muscular dystrophies that, significantly, works independently from specific genetic mutations, making it potentially suitable for all patients with DMD. …”
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A rare case of culture-negative infective endocarditis following cataract surgery by Gayashani K. Jayasinghe, Logeswaran Dinusha, Udara S. Perera, Indrakumar Jegarajah

“…Because infective endocarditis remains a significant public health concern with increasing incidence rates, we present this unusual case of culture-negative infective endocarditis following cataract surgery, highlighting the diagnostic and therapeutic challenges encountered.…”
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Novel intervention of high-frequency repetitive transcranial magnetic stimulation in patients with somatic symptom disorder and its safety and outcome by Nand Kumar, Prakamya Singal, Abhishek Chakladar

“…Double cone coil TMS at medial Prefrontal Cortex appears to be a safe therapeutic intervention with potentially good outcomes in SSDs.…”
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Colistin: The phoenix Arises by JM Conly, BL Johnston

“…The emergence of bacteria resistant to most classes of commercially available antibiotics and the shortage of novel antimicrobial agents with activity against gram-negative microorganisms have led to the reemergence of polymyxins as a valuable addition to the therapeutic armamentarium. It was thus considered timely to review colistin and its emerging role in managing infections due to MDR gram-negative bacteria.…”
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Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy by Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Qiyun Wang

“…Particular attention has been paid to the key regulators of the RCT pathway: LXR, ABCA1, and ABCG1 genes and their potential therapeutic targets in the management of DR.…”
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Efficacy and safety of dupilumab in a patient with metastatic clear cell renal cell carcinoma by César Ferreira, Egídio Freitas, Tiago Torres

“…This case suggests that dupilumab could be a viable treatment option for patients with AD and a history of solid neoplasms, filling a critical gap in current therapeutic approaches. Current evidence indicates that dupilumab does not promote cancer progression, but further research is necessary to confirm its long-term safety in this population. …”
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Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling by Melanie A. Simpson

“…Understanding the context for these HA signals offers new diagnostic and therapeutic insight.…”
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Durable disease regression with copanlisib treatment in PI3K-mutated metastasizing ameloblastoma: A case report by Meghan M Lynch, Pedro Hermida-Viveiros, Sean Stencel, Hannah Knott, Rusul Al-Maryati, Farres Obeidin, Borislav A Alexiev, Susan Abbinanti, Senthil Damodaran, Mark Agulnik, Seth M Pollack

“…This case highlights the potential of targeted therapies such as copanlisib for treating METAM, providing a promising therapeutic option for patients with PIK3CA mutations.…”
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White Matter Injury in Central Nervous System Disorders by Zheng L, Wang X, Li P, Hao Y, Zhang H, Chen H, Zheng Z

“…In this article, we will briefly describe the structure and function of white matter, summarize the pathological changes of WMI, and focus on the molecular mechanisms and therapeutic research advances in WMI after ischemic stroke, cerebral hemorrhage, Alzheimer’s disease, and multiple sclerosis diseases.Keywords: white matter injury, central nervous system, oligodendrocytes, myelin…”
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Ipilimumab: A First-in-Class  T-Cell Potentiator for Metastatic Melanoma by Bartosz Chmielowski

“…This agent provides an additional therapeutic option in metastatic melanoma, and guidelines for management of adverse events facilitate clinical implementation of this new agent.…”
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Sex Hormone Receptor Repertoire in Breast Cancer by Gerald M. Higa, Ryan G. Fell

“…Nonetheless, our understanding of regulatory molecules and resistance mechanisms remains incomplete, further compromising our ability to develop novel therapeutic strategies that could improve disease outcomes. …”
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Patient-derived induced pluripotent stem cell organoids for amyotrophic lateral sclerosis drug discovery by Wenyan Li, Jingqi Liu, Wenting Li, Lina Sun, Hao Zhang, Lei Gao, Chong Gao

“…Complex biological mechanisms and unidentified therapeutic targets for amyotrophic lateral sclerosis (ALS) significantly hinder the development of effective treatments. …”
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Cognitive Behavioral Therapy in Children and Adolescents with Anxiety Disorder by Emel KARAKAYA, Didem Behice ÖZTOP

“…Age and development level of the child should be particularly taken into account while using assessment tools and therapeutic modality [JCBPR 2013; 2(1.000): 10-24]…”
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Infiltrative Squamocellular Carcinoma of the Forearm in a Patient with Uncontrolled Psoriasis: Impact on Microsurgical Flap Viability and Microcirculation by Tamburello Sara, Guido Mauro, Francesco Mori, Menichini Giulio

“…We decided to review the literature and formulate a therapeutic protocol to tackle the critical aspects of psoriasis impacting on free-flap viability before reintervention. …”
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RNA-binding proteins as versatile metabolic regulators by Ellie Koletsou, Ina Huppertz

“…Taken together, this review provides a comprehensive overview of the critical interplay between RBPs and metabolism and offers insights into potential therapeutic targets for regenerative medicine and age-related diseases.…”
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