Safety of Cyclophosphamide Therapy in Autoimmune Rheumatic Diseases by Ramaswamy Subramanian, Himanshu Pathak, Vinod Ravindran

“…However, in the event of failure of aforementioned agents in aggressive rheumatic diseases or in a resource-limited setting, the usage of CYC continues to be a useful therapeutic strategy. In this review, we have appraised the adverse effects of CYC therapy in AIRDs which would help clinicians in taking informed decisions regarding CYC usage.…”
Get full text

Cognitive Behavioral Therapy in Children and Adolescents with Anxiety Disorder by Didem Behice ÖZTOP, Emel KARAKAYA

“…Age and development level of the child should beparticularly taken into account while using assessment tools and therapeutic modality.…”
Get full text

Treatment options of human demodicosis by Olga Pawełczyk

“…Objective: The aim of this paper is to review the therapeutic options used in the treatment of the ocular and cutaneous human demodicosis. …”
Get full text

Sexually Transmitted Infections by LE Nicolle

“…STIs continued unabated in developing countries, as many epidemiological and therapeutic studies explored the association of STIs with HIV infection.…”
Get full text

Secrets behind the Auricle: Angiolymphoid Hyperplasia with Eosinophilia by Tanmay Arora, Kewecho Akami, Atul Jain, Neeti Kapur

“…Effective management typically involves complete surgical excision, underscoring the significance of meticulous diagnosis to guide appropriate therapeutic strategies and ensure favorable outcomes in managing such intriguing clinical presentations.…”
Get full text

Role of Matrix Metalloproteinases in Angiogenesis and Its Implications in Asthma by Khuloud Bajbouj, Rakhee K. Ramakrishnan, Qutayba Hamid

“…This review focuses on the contribution of MMPs and the regulatory role exerted by them in angiogenesis and vascular remodeling in asthma as well as addresses their potential as therapeutic targets in ameliorating angiogenesis in asthma.…”
Get full text

The role of multiomics in revealing the mechanism of skin repair and regeneration by Shaoyan Shi, Xuehai Ou, Jafeng Long, Xiqin Lu, Siqi Xu, Gang Li

“…Integrative multiomics studies can also identify novel biomarkers and therapeutic targets for skin regeneration. Despite the technical and biological challenges, the future of multiomics in skin research holds great promise for advancing personalized medicine and improving wound healing strategies. …”
Get full text

Participation in residential child care in Germany by Bernhard Babic, Liane Pluto

“…Residential establishments in Germany combine everyday life with educational and therapeutic services in order that they either seek to ensure the return of the child or young person to his or her own family, or prepare them for living in another family. …”

Pathogenesis and regenerative therapy in vitiligo and alopecia areata: focus on hair follicle by Yuan Zhou, Yu-Xuan Zhang, Yu-Yun Xiong, Yu-Mei Li

“…This article reviews the role of hair follicles in the pathogenesis, clinical manifestations, and therapeutic options for vitiligo and AA, aiming to deepen clinicians’ understanding of follicular involvement in these diseases and explore potential treatment avenues.…”
Get full text

Clinical trials in health-care metaverse – A conceptual overview by J. Mohammed Sulaiman Sait, S. Sarumathy

“…Literature review has shown that the adoption of such technologies in the field of clinical trials can help in improving the therapeutic outcomes in patients while having numerous other benefits. …”
Get full text

NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis by Tian Tang, Feng Zeng

“…In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. Novel therapeutic targets for LSCC are urgently needed. lncRNAs exert important roles in various biological progressions, including LSCC. …”
Get full text

Interactions between Bacteriophages and Eukaryotic Cells by Ramendra Dirgantara Putra, Diana Lyrawati

“…Such interactions are crucial for understanding and developing bacteriophages as the therapeutic agents and pharmaceutical delivery systems. …”
Get full text

Exploring space: ethical dilemmas for catholicism by Maurizio Balistreri

“…While the Church generally supports space exploration, biotechnologies such as genome editing, assisted reproduction, and artificial wombs – technologies potentially essential for human survival and reproduction in space – clash with its moral principles. Non-therapeutic genetic modifications, regarded by the Church as an arbitrary redesign of human nature, are categorically prohibited. …”
Get full text

A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity by Andrew McGarry, Ruin Moaddel

“…<b>Conclusions:</b> Consistently identified targets that correlate with phenotype or progression may have value, if validated, as enrichment tools in clinical trials and potentially as markers of therapeutic response.…”
Get full text

Distinguishing between HPV-Associated Metastatic Anal Squamous Cell Cancer and HPV-Associated Oropharyngeal Cancer by Steven Sorscher

“…However, determining whether a site of squamous cell carcinoma represents distant metastatic ASCC versus a metastatic HPV-related metastasis from an OPSCC to a regional lymph node carries profound prognostic and therapeutic implications. A patient with a history of locally advanced ASCC treated with standard concurrent radiation therapy and chemotherapy in 2015 is described. …”
Get full text

Oncolytic Viruses: The Power of Directed Evolution by Maxine Bauzon, Terry W. Hermiston

“…., ability to replicate and spread) and/or an increased therapeutic window (i.e., differentiated replication and spread on tumor versus normal cells), both of which have potential value but the latter of which defines an oncolytic virus. …”
Get full text

Les représentations et rôles des soignants au regard des pratiques d’ETP by Claire Llambrich, Cécile Pouteau

“…In a second part, we describe the search-action driven with actors of care and with sick having for object the impact of the therapeutic education of the patient in diverse services. …”
Get full text

Mechanisms of oxidative stress-induced sperm dysfunction by Yutao Wang, Xun Fu, Hongjun Li

“…Further research is essential to enhance therapeutic approaches and improve reproductive outcomes.…”
Get full text

Review of Original Research, Processing Evolution, Chemical Constituents, and Pharmacological Effects of Semen Vaccariae by Yan-Feng Li, Ya-Shu Liu, Yuan-Liang Ai, Zheng Liu

“…Currently, research on the chemical constituents and pharmacological effects of SV has made little progress; however, the understanding of specific therapeutic mechanisms of action on clinical conditions, such as cardiovascular, prostate, and osteoporosis remains to be improved. …”
Get full text

INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES by E. Blum Hubert

“…Such data increasingly allow to define the individual disease predisposition and to predict disease prognosis as well as the efficacy of therapeutic strategies in the individual patient (‘personalized medicine’). …”
Get full text