Endothelial Progenitors as Tools to Study Vascular Disease by Reinhold J. Medina, Christina L. O'Neill, T. Michelle O'Doherty, Sarah E. J. Wilson, Alan W. Stitt

“…The use of OECs for modelling vascular disease will contribute greatly to improving our understanding of endothelial pathogenesis, which will potentially lead to the discovery of novel therapeutic strategies for vascular diseases.…”
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MicroRNA-Regulated Proinflammatory Cytokines in Sarcopenia by Jingjing Fan, Xianjuan Kou, Yi Yang, Ning Chen

“…In this paper, we have systematically discussed regulatory mechanisms of miRNAs for the expression and secretion of inflammatory cytokines during sarcopenia, which will provide some novel targets and therapeutic strategies for controlling aging-related atrophy of skeletal muscle and corresponding chronic inflammatory diseases.…”
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Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy by Natasha Gupta, Seema Ahmed, Lemuel Shaffer, Paula Cavens, Josef Blankstein

“…We report a case of severe gestational hypertriglyceridemia that caused acute pancreatitis at full term and was successfully treated with postpartum therapeutic plasma exchange. Patient also developed several other complications related to her substantial hypertriglyceridemia including preeclampsia, chylous ascites, retinal detachment, pleural effusion, and chronic pericarditis. …”
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Chinese Herbal Medicine in Ameliorating Diabetic Kidney Disease via Activating Autophagy by Yuyang Wang, Hailing Zhao, Qian Wang, Xuefeng Zhou, Xiaoguang Lu, Tongtong Liu, Yongli Zhan, Ping Li

“…The advances in our understanding regarding the treatment of DKD via regulating autophagy with Chinese herbal medicine will enhance the clinical application of Chinese medicine as well as discovery of novel therapeutic agents for diabetic patients.…”
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Structure and Function of the LRBA Protein by Ege Ezen, Mehmet Cihangir Çatak, Feyza Bayram Çatak, Sofia Piepoli, Pegah Zahedimaram, Ecem Ultanır, Safa Barış, Batu Erman

“…Sequence and domain structure similarities between the proteins suggest that a level of redundancy may be present, which could potentially result in new therapeutic avenues.…”
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Plasmablastic Lymphoma: A Systematic Review by Jorge J. Castillo, John L. Reagan

“…PBL represents a diagnostic challenge given its characteristic morphology and lack of CD20 expression, and also a therapeutic challenge, with early responses to therapy, but with high relapse rates and poor prognosis. …”
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From Bench to Clinic: Crosslinking Approaches for Next-Generation Collagen Fillers by Song-Yi Wu, Chen-Chi Tsai, Wei-Bor Tsai

“…The market for injectable dermal fillers expands yearly, with each product offering unique compositions that influence therapeutic outcomes, handling properties, and potential adverse effects. …”
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Parthenogenesis and Human Assisted Reproduction by Adriana Bos-Mikich, Fabiana F. Bressan, Rafael R. Ruggeri, Yeda Watanabe, Flávio V. Meirelles

“…Success in achieving a standardized artificial activation methodology for human oocytes and the subsequent potential therapeutic gain obtained from these embryos depends mainly on the availability of gametes donated from infertility treatments. …”
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A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research by Sun Young Lee, Mikael Klingeborn, Jeff W. M. Bulte, Daniel T. Chiu, Michael Chopp, Christopher W. Cutler, Saumya Das, Charles E. Egwuagu, Christie D. Fowler, Sarah F. Hamm‐Alvarez, Hakho Lee, Yutao Liu, Ben Mead, Tara L. Moore, Sriram Ravindran, Ashok K. Shetty, Johan Skog, Kenneth W. Witwer, Ali R. Djalilian, Alissa M. Weaver

“…Abstract With an evolving understanding and new discoveries in extracellular vesicle (EV) biology and their implications in health and disease, the significant diagnostic and therapeutic potential of EVs for vision research has gained recognition. …”
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Targeting Brain Drug Delivery with Macromolecules Through Receptor-Mediated Transcytosis by Yuanke Li, Ruiying Liu, Zhen Zhao

“…Advancements in macromolecules-based delivery systems for brain diseases are summarized, emphasizing their therapeutic potential and limitations. Finally, emerging RMT strategies, including viral vectors, exosomes, and boron neutron capture therapy, are discussed for their precision in brain-targeted treatments. …”
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The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications by Yingquan Liu, Peijia Hu, Hongliang Cheng, Fangyuan Xu, Yu Ye

“…This review comprehensively explores the role of glycolysis in different phases of IS, addresses existing controversies, and discusses its diagnostic and therapeutic applications. By elucidating the intricate relationship between glycolysis and IS, this review aims to provide novel insights for future research and clinical advancements.…”
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Effects of Various Flavonoids on the α-Synuclein Fibrillation Process by Xiaoyun Meng, Larissa A. Munishkina, Anthony L. Fink, Vladimir N. Uversky

“…Currently, there is no approved therapeutic agent directed toward preventing the protein aggregation, which has been recently shown to have a key role in the cytotoxic nature of amyloidogenic proteins. …”
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DNA Vaccination: Using the Patient's Immune System to Overcome Cancer by Georg Eschenburg, Alexander Stermann, Robert Preissner, Hellmuth-Alexander Meyer, Holger N. Lode

“…This requires the development of therapeutic strategies which are as effective as standard therapies but permit the patients a life without severe negative side effects. …”
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Vulnerable Narcissism and Internet Addiction: Exploring Mediating Pathway through Vengeance by Ozkan Cikrikci, Ragip Umit Yalcin

“…The possible potential therapeutic power of vulnerable narcissism, which may lead to a direct increase in vengeance and an indirect increase in internet addiction through vengeance, appeared in line with this perspective. …”
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Hemin Augments Growth and Hemoglobinization of Erythroid Precursors from Patients with Diamond-Blackfan Anemia by Eitan Fibach, Memet Aker

“…Moreover, its beneficial effect in culture suggests a therapeutic potential.…”
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The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival by Changjun He, Haiquan Qiao, Hongchi Jiang, Xueying Sun

“…The paper also discusses the clinical significance of investigating B7-H4 as potential markers for cancer diagnosis and prognosis, and as therapeutic targets.…”
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Silica Nanoparticles Effects on Blood Coagulation Proteins and Platelets by Volodymyr Gryshchuk, Natalya Galagan

“…Interaction of nanoparticles with the blood coagulation is important prior to their using as the drug carriers or therapeutic agents. The aim of present work was studying of the primary effects of silica nanoparticles (SiNPs) on haemostasis in vitro. …”
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A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA by Guojuan Sun, Ling He

“…Accordingly, ICD-related ncRNAs hold promise as novel therapeutic targets for optimizing the efficacy of cancer immunotherapy. …”
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Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases by Mônica Fernandes Gomes, Luigi Giovanni Bernardo Sichi, Lilian Chrystiane Giannasi, José Benedito Oliveira Amorim, João Carlos da Rocha, Cristiane Yumi Koga-Ito, Miguel Angel Castillo Salgado

“…The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. …”
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Marfan syndrome: insights from animal models by Yuanyuan Jiang, Ping Jia, Xiaoying Feng, Dingding Zhang

“…This review is to describe the TGF-β signaling pathway in MFS and the potential application of animal models to provide new therapeutic strategies for patients with MFS.…”
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