Lactose-free milk powder can effectively relieve diarrhea symptoms in weaning SD rats and children by Manman Liu, Shiwen Han, Boya Li, Cheng Chen, Lu Yao, Jung-il Kwon, Juan Jin, Huilian Che

“…In this study, we evaluated the therapeutic effects of lactose-free milk powder on rats and children with diarrhea. …”
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The Clinicians’ Guide to Large Language Models: A General Perspective With a Focus on Hallucinations by Dimitri Roustan, François Bastardot

“…The implications for clinical practice range from the generation of inaccurate diagnostic and therapeutic information to the reinforcement of flawed diagnostic reasoning pathways, as well as a lack of reliability if not used properly. …”
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Human Immunodeficiency Virus Infection and Hodgkin's Lymphoma in South Africa: An Emerging Problem by Moosa Patel, Vinitha Philip, Fatima Fazel

“…However, the advent of HAART has brought renewed hope, allowing standard therapeutic options to be used more optimally, with better treatment outcomes. …”
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Helicobacter pylori and the microbiome in gastric cancer development and treatment: A year in review by P. Vieira, M. Barbedo-Tavares, C. Figueiredo

“…The integration of findings on the complex interplay of H. pylori and the microbiome in cancer initiation and progression will be crucial for the development of more effective prevention and therapeutic strategies.…”
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Successful treatment of a keloid on the upper lip by trepanation and radiotherapy: a case report by Xianghui Li, Yong Wei, Zhuren Ruan, Gao Wei, Zhijian Yao

“…Traditional treatments, such as intralesional injections, laser therapy, and surgical excision, have shown limited efficacy and are associated with high recurrence rates.Materials and methods: In a recent case, a 19-year-old male with a keloid on the upper lip did not respond to local injections of triamcinolone acetonide (TAC) or carbon dioxide ablative fractional resurfacing laser therapy.Results: A combined treatment approach involving trepanation and superficial radiotherapy successfully flattened the keloid tissue, with no recurrence observed during a 3-year follow-up period.Conclusions: This case underscores the potential efficiency and safety of combined therapeutic interventions and contributes valuable evidence towards the development of novel treatment strategies for keloids.…”
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THE ROLE OF ERYTHROPOIETIN IN TREATMENT OF ANEMIA IN CANCER PATIENTS by P. G. Berezin, V. V. Milovanov, A. A. Ivannikov

“…Recommendations are given on the optimal dose of the drug in order to obtain the most pronounced clinical effect of treatment, increasing the therapeutic dose of the drug with an insufficient increase in the hemoglobin level by 100% or more allows an individual approach to the correction of anemia. …”
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Unlocking the potential of antimicrobial peptides: Beta-defensins and the future of cancer diagnostics by Saranya Velmurugan, Gowtham Kumar Subbaraj

“…Further research on beta defensins’ mechanisms and broader oncological implications is crucial for innovative therapeutic strategies.…”
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Structure‐based computational design of antibody mimetics: challenges and perspectives by Elton J. F. Chaves, Danilo F. Coêlho, Carlos H. B. Cruz, Emerson G. Moreira, Júlio C. M. Simões, Manassés J. Nascimento‐Filho, Roberto D. Lins

“…The design of antibody mimetics holds great promise for revolutionizing therapeutic interventions by offering alternatives to conventional antibody therapies. …”
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Glioma Stem Cells: Signaling, Microenvironment, and Therapy by Brandon D. Liebelt, Takashi Shingu, Xin Zhou, Jiangong Ren, Seul A. Shin, Jian Hu

“…In this review, the authors summarize the current knowledge of GSC biology and function and the role of GSCs in new vascular formation within glioblastoma and discuss potential therapeutic approaches to target GSCs.…”
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Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis by Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevliya Ocal Demir, Ahmet Soysal, Mustafa Bakir

“…Epstein-Barr virus-related neurological disorders include meningitis, encephalitis, and cranial or peripheral neuritis, which are mostly seen in immunocompromised patients. The therapeutic modalities for EBV-related severe organ damage including central nervous system manifestations are still uncertain. …”
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The Use of Benzodiazepines in the Management of Hypertensive Crisis: A Literature Review by Łukasz Stojak, Mateusz Grego, Mateusz Baczewski, Dariusz Popiela, Karina Urbańska, Katarzyna Grego, Filip Kwiatkowski, Witold Czyż

“…Benzodiazepines should be used with caution as a therapeutic option in hypertensive crisis management. …”
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Role of heat shock protein in radiation-induced effect and related potential clinical application by Ying Xu, Wentao Hu, Guangming Zhou

“…This paper reviews the biological effects of HSP under radiation and the latest research progress of combined radiation and HSP inhibitors or hyperthermia, in the hope of having a more comprehensive understanding of its mechanism in physiological processes such as cell survival, apoptosis, inflammation, immune response, as well as radiation response, which will help to enhance the therapeutic effect and to provide more effective and safer radiotherapy for cancer patients in the future.…”
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Assessing the Burden of Neglected Tropical Diseases in Low-Income Communities: Challenges and Solutions by Francesco Branda, Abdisalam Yusuf Ali, Giancarlo Ceccarelli, Mattia Albanese, Erica Binetti, Marta Giovanetti, Massimo Ciccozzi, Fabio Scarpa

“…This paper analyzes the factors that perpetuate the burden of NTDs, highlighting how poor health infrastructure, unfavorable socioeconomic conditions and lack of therapeutic resources exacerbate their impact. The effectiveness of current interventions, such as mass drug administration (MDA) programs and improved sanitation, in reducing disease prevalence is examined. …”
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E. coli-Produced BMP-2 as a Chemopreventive Strategy for Colon Cancer: A Proof-of-Concept Study by Saravanan Yuvaraj, Sa’ad H. Al-Lahham, Rajesh Somasundaram, Patrick A. Figaroa, Maikel P. Peppelenbosch, Nicolaas A. Bos

“…Colon cancer is a serious health problem, and novel preventive and therapeutical avenues are urgently called for. Delivery of proteins with anticancer activity through genetically modified bacteria provides an interesting, potentially specific, economic and effective approach here. …”
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Conditional Inactivation of HIF-1 Using Intrabodies by Arjan J. Groot, Eelke H. Gort, Elsken van der Wall, Paul J. van Diest, Marc Vooijs

“…HIF-1 activation is associated with tumor aggressiveness and poor clinical outcome and, therefore, may provide an attractive therapeutic target. Here we provide a novel approach for HIF-1 targeted therapy using single-domain llama antibodies directed against the HIF-1α oxygen dependent degradation domain which encompass the N-terminal transactivation domain. …”
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Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin by Céline Hivelin, Sophie Béraud-Dufour, Christelle Devader, Amar Abderrahmani, Sébastien Moreno, Hamid Moha ou Maati, Alaeddine Djillani, Catherine Heurteaux, Marc Borsotto, Jean Mazella, Thierry Coppola

“…Inhibition of the potassium channels TREK-1 by spadin (SPA) is currently thought to be a promising therapeutic target for the treatment of depression. …”
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To Use or Not to Use Metformin in Cerebral Ischemia: A Review of the Application of Metformin in Stroke Rodents by Isaac Arbeláez-Quintero, Mauricio Palacios

“…Searching for potential therapeutic strategies to prevent and treat stroke is necessary, given the increase in overall life expectancy. …”
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Multitarget CDK inhibitors roscovitine and UCN‑01 induce apoptosis in colorectal cancer cells by inhibiting cell cycle progression and transcription by Sonal Mohan Manohar, Kalpana Sanjay Joshi

“…Thus, we demonstrate that multiple CDK inhibition offers promising therapeutic strategy against CRC.…”
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Amniotic-Fluid Stem Cells: Growth Dynamics and Differentiation Potential after a CD-117-Based Selection Procedure by S. Arnhold, S. Glüer, K. Hartmann, O. Raabe, K. Addicks, S. Wenisch, M. Hoopmann

“…In order to show stem cell characteristics such as pluripotency and to evaluate a possible therapeutic application of these cells, AF fluid-derived stem cells were differentiated along the adipogenic, osteogenic, and chondrogenic as well as the neuronal lineage under hypoxic conditions. …”
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Gut Microbiota and Its Impact on Brain Function and Mental Health by Zofia Martyna Wójcik, Katarzyna Kamińska-Omasta, Bartosz Omasta, Olga Krupa, Paulina Dorota Pietrukaniec, Kuba Borys Romańczuk, Kinga Furtak, Szymon Przemysław Stolarczyk, Magdalena Agata Czerska, Daria Rybak

“…This paper reviews literature on the impact of gut microbiota on mental health, focusing on gut-brain axis mechanisms, diet, and therapeutic potential. These findings are especially relevant for personalized medicine approaches targeting microbiota to manage mental disorders. …”
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