Roles of Inflammasomes in Inflammatory Kidney Diseases by Jinjin Fan, Kaifeng Xie, Liqin Wang, Nuoyan Zheng, Xueqing Yu

“…Here, we discuss the mechanism in which inflammasomes occur, as well as their roles in inflammatory kidney diseases, in order to shed light for discovering new therapeutical targets for the prevention and treatment of inflammatory kidney diseases and consequent end-stage renal disease.…”
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The Immune Landscape and Its Potential for Immunotherapy in Advanced Biliary Tract Cancer by Andry Santoso, Iris Levink, Rille Pihlak, Ian Chau

“…This review appraises our current understanding of the immune landscape of advanced BTC, including emerging transcriptome-based classifications, highlighting the mechanisms of immune evasion and resistance to ICI and their therapeutic implications. It describes the shifting treatment paradigm from traditional chemotherapy to immunotherapy combinations as well as the potential biomarkers for predicting response to ICI.…”
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Modularity as a strategy for medical design by Carla Langella, Salvatore Carleo, Marianna De Luca

“…Design comes into play when unresolved challenges arise, mainly related to the usability of biomedical products, especially in the field of physical and rehabilitative medicine, where aids used for therapeutic treatments and exercises are often inadequate for scientific advancements and the complex needs of patients and therapists. …”
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Hyperlipidaemia treatment and gut microbiology by Liu Zhe, Liu Zhe, Yu ChunLi

“…In this review, we summarize the mechanism and relationship between the pathogenesis of hyperlipidaemia and gut microbiota, and the mechanism of hyperlipidaemia treatment by influencing the gut microbiota in various treatment modalities, which provides diversified therapeutic ideas and scientific basis for clinical treatment. …”
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Myocardial Damage in SARS-CoV-2 Infection by Elizabeth Sellén Sanchén, Joaquín Sellén Crombet, Lisandra Sellén Fundora

“…Patients with a history of arterial hypertension, coronary heart disease and cardiomyopathy constitute a very high risk population of complications from the coronavirus. Therapeutic behavior must be prioritized and intensive. …”
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Carcinogenic and anticancer activities of microbiota-derived secondary bile acids by Mobina Kouhzad, Friedrich Götz, Tahereh Navidifar, Elahe Taki, Mahsa Ghamari, Roghayeh Mohammadzadeh, Maryam Seyedolmohadesin, Narjess Bostanghadiri

“…The article also discusses the complex interplay between SBAs and the host’s genetic and environmental factors, highlighting potential therapeutic implications and the need for targeted strategies to mitigate risks while harnessing beneficial effects. …”
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Knee Osteoarthritis Treatment with the KineSpring Knee Implant System: A Report of Two Cases by David A. Hayes, Larry E. Miller, Jon E. Block

“…Consequently, there is a therapeutic need for alternative knee OA treatments that directly address joint overload to fill the gap between ineffective conservative care and invasive joint-modifying surgical procedures. …”
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Victory Gardeners: Food and Gardening as part of a Healthy Lifestyle and Community by Maxine Hunter, William J. Lester, Hannah Wooten, Erin E. Harlow, Tiare Silvasy, LuAnn Duncan, Rebecca Elliott, Samantha DeForge, Danielle Treadwell

“… Healthy lifestyles, victory gardens, and Blue Zones are familiar terms to most, and each incorporates a holistic approach to human well-being. The therapeutic and nutritional benefits of gardening have long been recognized. …”
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Advancing diagnosis and treatment for human African trypanosomiasis in Nigeria: challenges and future directions by Kelly Zongo, Rolayo Toyin Emmanuel

“…We discuss the potential of simple and rapid molecular diagnostics, particularly the lyophilized LAMP test, as a game-changer in resource-limited settings and the need for a national repository of drugs to ensure timely therapeutic interventions. This article also explores future directions for the elimination of HAT in Nigeria, highlighting the importance of policy reforms and increased investment in diagnostic infrastructure.…”
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CULTURAL AND HISTORICAL ESSENCE OF IRONY IN MODERN PHILOSOPHY КУЛЬТУРНО-ИСТОРИЧЕСКАЯ СУЩНОСТЬ ИРОНИИ В СОВРЕМЕННОЙ ФИЛОСОФИИ КУЛЬТУРНО-ІСТОРИЧНА ВИЗНАЧЕНІСТЬ ІРОНІЇ У СУЧАСНІЙ ФІЛО... by S. M. Geiko

“…The possibility of «irony» therapeutical function
 execution in post modernistic style of philosophical research is proved.…”
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Recent advances in the role of high-salt diet in anti- and pro-cancer progression by Shiwei Tang, Juan Xu, Ping Wan, Ping Wan, Ping Wan, Shumen Jin, Ying Zhang, Ying Zhang, Linting Xun, Linting Xun, Jinli Wang, Jinli Wang, Mei Luo, Mei Luo, Wenjie Chen, Wenjie Chen, Zan Zuo, Zan Zuo, Zan Zuo, Hui Tang, Hui Tang, Jialong Qi, Jialong Qi, Jialong Qi, Jialong Qi, Jialong Qi

“…The objective of this review is to explore whether HSD could be a potential future oncological therapeutic strategy under specific situation.…”
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Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury by Xiao Zhang, Manrui Li, Yang Xu, Jingting Wu, Ruixuan Yuan, Yihan Sun, Xiaogang Chen, Meili Lv, Bo Jin, Xiameng Chen, Weibo Liang

“…These results highlight Tyro3 as a promising therapeutic target for TBI.…”
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Dynamic Changes in the Nigrostriatal Pathway in the MPTP Mouse Model of Parkinson’s Disease by Dongping Huang, Jing Xu, Jinghui Wang, Jiabin Tong, Xiaochen Bai, Heng Li, Zishan Wang, Yulu Huang, Yufei Wu, Mei Yu, Fang Huang

“…This article will assist with the development of interventions or therapeutic strategies for PD.…”
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Successfully Treated Norovirus- and Sapovirus-Associated Diarrhea in Three Renal Transplant Patients by Noha Ghusson, Gustavo Vasquez

“…To examine the burden of norovirus- and sapovirus-related diarrhea in renal transplant patients and to propose the use of nitazoxanide as a therapeutic option for treatment. Methods. We reviewed three renal transplant patients with viral diarrhea requiring hospitalization due to acute renal failure and signs of graft rejection. …”
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Lobar lung transplantation, followed by partial sternal resection and bronchial stenosis, in a patient with scoliosis by Monika Svorcova, Jiri Vachtenheim, Jan Simonek, Jaromir Vajter, Zuzana Prikrylova, Jan Kolarik, Jiri Pozniak, Jan Havlin, Robert Lischke

“…Chest opening is a routine intraoperative primary therapeutic procedure after lung transplantation in unstable patients with oversized transplanted lungs. …”
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Mitochondrial disease and epilepsy in children by Xuan Zhang, Xuan Zhang, Xuan Zhang, Bo Zhang, Bo Zhang, Bo Zhang, Zhiming Tao, Zhiming Tao, Zhiming Tao, Jianmin Liang, Jianmin Liang, Jianmin Liang

“…This review explores common mitochondrial diseases associated with epilepsy, focusing on their prevalence, seizure types, EEG features, therapeutic strategies, and outcomes. It also summarizes the relationship between the molecular genetics of mitochondrial respiratory chain components and the development of epilepsy.…”
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Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review by Vuyolwethu Khwaza, Blessing A. Aderibigbe

“…The essential components of EOs have been recognized for diverse therapeutic activities and have gained significant attention for their potential antibacterial activities. …”
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Molecular landscape of salivary gland malignancies. What is already known? by Julia Pikul, Anna Rzepakowska

“…This may lead to difficulties in terms of diagnostic accuracy and suitable therapeutic selection. Mucoepidermoid carcinoma occurs most frequently and is characterised by gradual disease progression. …”
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Local Bone Marrow Renin-Angiotensin System and Atherosclerosis by Yavuz Beyazit, Tugrul Purnak, Gulay Sain Guven, Ibrahim C. Haznedaroglu

“…Therefore, AT1R blocking not only in vascular cells but also in the BM could be an important therapeutic approach to prevent atherosclerosis. The aim of this paper is to review the function of local BM RAS in the pathogenesis of atherosclerosis.…”
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Multisystemic Side Effects of an Indispensable Old Drug: A Case Report of Chronic Lithium Use (A Patient with Multiple Side Effects of Lithium) by Levent Demirtas, Emin Murat Akbas, Husnu Degirmenci, Ali Gurel, Eren Duzgun

“…To avoid toxicity, close follow-up and clinical supervision are important for the early diagnosis and treatment of these side effects, due to the narrow therapeutic index and obscure clinical signs and symptoms of toxicity.…”
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