High Grade Myofibroblastic Sarcoma of Paratesticular Soft Tissues by Ioannis Anastasiou, Panagiotis K. Levis, Ioannis Katafigiotis, Georgios Karaolanis, Viktoria-Varvara Palla, Evangelos Felekouras, Antonios Athanasiou, Marina Perdiki, Dionysios Mitropoulos, Constantinos A. Constantinides

“…Paratesticular tumors, despite their rarity, present a high incidence of malignancy (30%), and the therapeutic approach of choice is surgical resection with negative margin. …”
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Technical Review on Endoscopic Treatment Devices for Management of Upper Gastrointestinal Postsurgical Leaks by Renato Medas, Eduardo Rodrigues-Pinto

“…Nowadays, endoscopy is considered the first-line approach for their management, however, there is no definite consensus on the most appropriate therapeutic approach. There is a wide diversity of endoscopic options, from close-cover-divert approaches to active or passive internal drainage approaches. …”
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Intravenous Immunoglobulins: Mode of Action and Indications in Autoimmune and Inflammatory Dermatoses by Lyubomir A. Dourmishev, Dimitrina V. Guleva, Ljubka G. Miteva

“…In dermatology, IVIGs are administered for treatment of different disorders at different therapeutic regimens, mostly with higher doses then those administered for treatment of infectious diseases. …”
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Safety Issues Concerning the Medical Use of Cannabis and Cannabinoids by Mark A Ware, Vivianne L Tawfik

“…There is a need for long-term safety monitoring of patients using cannabinoids for a wide variety of conditions, to further guide therapeutic decisions and public policy.…”
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Eosinophilic gastroenteritis – a manifestation of an allergic disease in the gastrointestinal tract? Part 2. Treatment by Andrzej Kuźmiński, Tomasz Rosada, Justyna Przybyszewska, Natalia Ukleja-Sokołowska, Zbigniew Bartuzi

“…Patients with mild disease can be treated symptomatically, while patients with more severe symptoms or malabsorption symptoms require more aggressive therapy. So far, several therapeutic options have been proposed, including the following: dietary treatment, glucocorticosteroids, inhibitors of leukotriene receptors, mast cell stabilizers, immunomodulating drugs, and biological drugs. …”
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Modeling Musculoskeletal Disorders in Zebrafish: Advancements in Muscle and Bone Research by Luca Dalle Carbonare, Michele Braggio, Arianna Minoia, Mattia Cominacini, Maria Grazia Romanelli, João Pessoa, Natascia Tiso, Maria Teresa Valenti

“…These findings have also advanced our understanding of disease mechanisms and facilitated the development of potential therapeutic strategies for musculoskeletal disorders.…”
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Advances in micro-/nanorobots for cancer diagnosis and treatment: propulsion mechanisms, early detection, and cancer therapy by Baiyang Fu, Dan Luo, Chao Li, Yiwen Feng, Wenlong Liang

“…This review examines the current state of MNR applications and outlines future directions for their development, with the aim of enhancing their diagnostic and therapeutic efficacy and facilitating their integration into clinical practice.…”
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Alternative Cell Death Pathways and Cell Metabolism by Simone Fulda

“…A better understanding of these signal transduction mechanisms will likely contribute to open new avenues to exploit our knowledge on the regulation of necroptosis signaling for therapeutic application in the treatment of human diseases.…”
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Congenital Lumbar Hernia with Lumbocostovertebral Syndrome: A Case Report and Review of the Literature by Ketan Vagholkar, Khojasteh Dastoor

“…A case of congenital lumbar hernia associated with lumbocostovertebral syndrome is presented in view of its rarity and diagnostic and therapeutic challenges. Discussion. Anatomical background of congenital lumbar hernia associated with various other anomalies especially of the musculoskeletal structures is discussed. …”
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Vaccination ARN messager (ARNm), modèle de transition de la biologie fondamentale à la médecine by Sansonetti, Philippe J.

“…Sixty years of doubts for some and certainties for others about the possibility of using mRNA—an example of synthetic biology—in therapeutic medicine and vaccinology. Years of “translational” research and development have culminated in the success of anti-Covid-19 mRNA vaccines and the promise of more to come against emerging pathogens. …”
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Progress in nanomedicine for sonodynamic immunotherapy of tumors by Ziyan Feng, Ziyao Wang, Xi Xiang, Liyun Wang, Fangxue Du, Xueyang Xiao, Bihui Zhu, Xiao Rong, Li Qiu

“…Cancer remains a leading cause of mortality worldwide, with conventional treatments, such as chemotherapy and immunotherapy, exhibiting limitations, such as drug resistance and immune evasion. Therefore, novel therapeutic strategies are required. Sonodynamic therapy has emerged as an innovative approach in which sonosensitizers are activated by ultrasound to achieve antitumor effects through mechanisms, such as cavitation, thermal effects, and reactive oxygen species generation. …”
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Based on the immune system: the role of the IL-2 family in pancreatic disease by Yuqing Zhu, Zheng Lu, Zhuo Wang, Jiao Liu, Ke Ning

“…In this paper, we review the structural and functional characteristics of IL-2 family members, focus on their molecular mechanisms in pancreatic diseases including acute pancreatitis, chronic pancreatitis and pancreatic cancer, and highlight the importance of the related proteins in the regulation of immune response and disease progression, which will provide valuable insights for new biomarkers in pancreatic diseases, early diagnosis of the diseases, assessment of the disease severity, and development of new therapeutic regimens. The insights of the study are summarized in the following sections.…”
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Cienfuegos Medical Sciences Faculty contribution to the use of computer technology in higher medical teaching. Review of the clinical simulations use from 1990 to 2007 by Luis Alberto Corona Martínez, Mercedes Fonseca Hernández

“…Among the identified events are: the development and introduction of simulations in the Internal Medicine subject corresponding to the third year of the degree (course 1990-1991); the introduction of simulation, for evaluation purposes, in the Internal Medicine internship (1997-2000); the development of a new software for the elaboration of simulations (2002); and the extension of the use of simulations to therapeutic update seminars corresponding to the Pediatrics internship (2007). …”
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Safety of brigatinib following alectinib-induced-pneumonitis: Case report by Blerina Resuli, Heidi Galarza, Laura Elsner, Diego Kauffmann-Guerrero, Jürgen Behr, Amanda Tufman

“…While further descriptions are needed, our experience suggests that switching to a second ALK-TKI may be a safe therapeutic option in some patients who develop drug-induced pneumonitis on ALK TKIs.…”
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EXPLORATION OF CHEMICAL CONTENT AND ANTIBACTERIAL ACTIVITY OF SENDOK LEAVES (Plantago Major) USING AL-QUR'AN RECITATION THERAPY by Leni Legasari, Ana Maghpiroh, Muyasaroh Muyasaroh

“…The aim of this study is to explore the effect of spiritual methods on enhancing the therapeutic properties of Sendok leaves. After being treated with Qur'anic recitation, the leaves of the plant were analyzed for their chemical content, and bioactivity testing was carried out. …”
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Research progress of artificial intelligence in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer by Wei Wei, Menghang Ma, Zhenyu Liu

“…The incorporation of neoadjuvant chemotherapy into comprehensive management strategies for breast cancer underscores the importance of the precise prognostication of therapeutic efficacy. In clinical diagnostics, medical imaging has emerged as a critical tool for delineating the structural transformations within breast cancer tumors resulting from pharmacological interventions. …”
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Exploring the role of oxidative stress in carotid atherosclerosis: insights from transcriptomic data and single-cell sequencing combined with machine learning by Yiqin Yang, Mei Dong

“…It introduced novel insights into the mechanisms underlying carotid atherosclerosis formation and plaque progression and may assist in identifying potential therapeutic targets for their treatment.…”
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The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects by Galina S. Bogatkevich, Kristin B. Highland, Tanjina Akter, Richard M. Silver

“…We conclude that PPARγ agonists warrant consideration as potential antifibrotic drugs in patients with SSc-ILD. Differential therapeutic effects might be anticipated especially relative to racial differences and the functional expression of the c-Met receptor.…”
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The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review by Jed W. Fahey, Mirran Raphaely

“…The health-promoting, preventive, protective, and therapeutic applications of the natural compound sulforaphane (SF) produced from its biogenic precursor in broccoli, glucoraphanin, are extremely well established. …”
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Fractional Electrodamage in A549 Human Lung Cancer Cells by Hilario Martines-Arano, Jose Alberto Arano-Martinez, Manuel Alejandro Mosso-Pani, Alejandra Valdivia-Flores, Martin Trejo-Valdez, Blanca Estela García-Pérez, Carlos Torres-Torres

“…These findings advance our understanding of cellular responses to electrical fields and provide insights into applications in cancer diagnostics, monitoring, and potential therapeutic treatments.…”
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